Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia

Blood Coagulation and Fibrinolysis

Volumn 21, Issue 1, 2010, Pages 28-34

  Tantawy, Azza A G ^a   El Bostany, Eman A ^b   Adly, Amira A M ^a   Abou El Asrar, Mohammed ^a   El Ghouroury, Eman A ^c   Abdulghaffar, Esmat E ^c  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b Pediatric and Clinical Pathology Departments   (Egypt)

^c NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Acute lymphoblastic leukemia; Methotrexate toxicity; Methylene tetrahydrofolate reductase gene polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); METHOTREXATE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RELAPSE; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; DISEASE DURATION; DNA POLYMORPHISM; DRUG DOSE REGIMEN; DRUG MEGADOSE; EGYPT; FEMALE; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LIVER TOXICITY; MALE; MUCOSA INFLAMMATION; NEUTROPENIA; OVERALL SURVIVAL; PRESCHOOL CHILD; PRIORITY JOURNAL; WILD TYPE;

6-MERCAPTOPURINE; ALLELES; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASPARAGINASE; CHILD; CHILD, PRESCHOOL; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DRUG-INDUCED LIVER INJURY; EGYPT; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; METHOTREXATE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NEOPLASM PROTEINS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREDNISONE; RECURRENCE; STOMATITIS; VINCRISTINE;

EID: 75649124222     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e32833135e9     Document Type: Article

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