Effect of long- and short-term treatments with pravastatin on diabetes mellitus and pancreatic fibrosis in the Otsuka-Long-Evans-Tokushima Fatty rat

British Journal of Pharmacology

Volumn 159, Issue 2, 2010, Pages 462-473

  Otani, M ^a   Yamamoto, Mitsuyoshi ^a   Harada, M ^a   Otsuki, M ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Diabetes mellitus; OLETF rat; Pancreatic fibrosis; Pravastatin; Superoxide dismutase; Transforming growth factor 1

Indexed keywords

PRAVASTATIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DIABETES MELLITUS; DOSE TIME EFFECT RELATION; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; NONHUMAN; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOSE TISSUE, WHITE; ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CHOLESTEROL; DIABETES MELLITUS, TYPE 1; FATTY ACIDS, NONESTERIFIED; FIBROSIS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INSULIN; INSULIN RESISTANCE; MALE; ORGAN SIZE; PANCREAS; PEROXIDASE; PRAVASTATIN; RATS; RATS, LONG-EVANS; SUPEROXIDE DISMUTASE; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 75649086459     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00548.x     Document Type: Article

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