Central command and metaboreflex cardiovascular responses to sustained handgrip during microgravity

Respiratory Physiology and Neurobiology

Volumn 169, Issue SUPPL., 2009, Pages

  Karlsson, Lars L ^a   Montmerle, Stéphanie ^b   Rohdin, Malin ^a   Linnarsson, Dag ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

Author keywords

Blood pressure; Deconditioning; Heart rate; Isometric exercise; Weightlessness

Indexed keywords

ADULT; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR FUNCTION; ELECTROCARDIOGRAPHY; FEMALE; HAND STRENGTH; HEART RATE; HEMODYNAMICS; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; PHYSIOLOGY; PRESSORECEPTOR REFLEX; SPACE FLIGHT; WEIGHTLESSNESS;

ADULT; BAROREFLEX; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; ELECTROCARDIOGRAPHY; FEMALE; HAND STRENGTH; HEART RATE; HEMODYNAMICS; HUMANS; MALE; MIDDLE AGED; SPACE FLIGHT; WEIGHTLESSNESS;

EID: 75549085200     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2009.04.011     Document Type: Article

References (19)

1. Alam, M., Smirk, F.H., 1937. Observations in man upon a blood pressure raising reflex arising from the voluntary muscles. J. Physiol. 89, 372-383.
2. Buckey Jr., J.C., Lane, L.D., Levine, B.D., Watenpaugh, D.E., Wright, S.J., Moore, W.E., Gaffney, F.A., Blomqvist, C.G., 1996. Orthostatic intolerance after spaceflight. J. Appl. Physiol. 81, 7-18.
3. Convertino, V.A., 1996. Exercise and adaptation to microgravity environments. In: Soc, A.P. (Ed.), Handbook of Physiology, vol. 2. Environmental Physiology, Bethesda, MD, pp. 815-844.
4. Di Rienzo, M., Castiglioni, P., Iellamo, F., Volterrani, M., Pagani, M., Mancia, G., Karemaker, J.M., Parati, G., 2008. Dynamic adaptation of cardiac baroreflex sensitivity to prolonged exposure to microgravity: data from a 16-day spaceflight. J. Appl. Physiol. 105, 1569-1575.
5. Essfeld, D., Baum, K., Hoffmann, U., Stegemann, J., 1993. Effects of microgravity on interstitial muscle receptors affecting heart rate and blood pressure during static exercise. Clin. Invest. 71, 704-709.
6. Ferretti, G., Antonutto, G., Denis, C., Hoppeler, H., Minetti, A.E., Narici, M.V., Desplanches, D., 1997. The interplay of central and peripheral factors in limiting maximal O2 consumption in man after prolonged bed rest. J. Physiol. 501 (Pt 3), 677-686.
7. Fitts, R.H., Riley, D.R., Widrick, J.J., 2000. Physiology of a microgravity environment invited review: microgravity and skeletal muscle. J. Appl. Physiol. 89, 823-839.
8. Fu, Q., Levine, B.D., Pawelczyk, J.A., Ertl, A.C., Diedrich, A., Cox, J.F., Zuckerman, J.H., Ray, C.A., Smith, M.L., Iwase, S., Saito, M., Sugiyama, Y., Mano, T., Zhang, R., Iwasaki, K., Lane, L.D., Buckey Jr., J.C., Cooke, W.H., Robertson, R.M., Baisch, F.J., Blomqvist, C.G., Eckberg, D.L., Robertson, D., Biaggioni, I., 2002. Cardiovascular and sympathetic neural responses to handgrip and cold pressor stimuli in humans before, during and after spaceflight. J. Physiol. 544, 653-664.
9. Iellamo, F., Di Rienzo, M., Lucini, D., Legramante, J.M., Pizzinelli, P., Castiglioni, P., Pigozzi, F., Pagani, M., Parati, G., 2006. Muscle metaboreflex contribution to cardiovascular regulation during dynamic exercise in microgravity: insights from mission STS-107 of the space shuttle Columbia. J. Physiol. 572, 829-838.
10. Kamiya, A., Iwase, S., Michikamia, D., Fua, Q., Mano, T., 2000. Muscle sympathetic nerve activity during handgrip and post-handgrip muscle ischemia after exposure to simulated microgravity in humans. Neurosci. Lett. 280, 49-52.
11. Kamiya, A., Michikami, D., Shiozawa, T., Iwase, S., Hayano, J., Kawada, T., Sunagawa, K., Mano, T., 2004. Bed rest attenuates sympathetic and pressor responses to isometric exercise in antigravity leg muscles in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R844-850.
12. Kaufman, M.P., Hayes, S.G., 2002. The exercise pressor reflex. Clin. Auton. Res. 12, 429-439.
13. Kitamura, K., Jorgensen, C.R., Gobel, F.L., Taylor, H.L., Wang, Y., 1972. Hemodynamic correlates of myocardial oxygen consumption during upright exercise. J. Appl. Physiol. 32, 516-522.
14. O'Leary, D.S., 1993. Autonomic mechanisms of muscle metaboreflex control of heart rate. J. Appl. Physiol. 74, 1748-1754.
15. Pagani, M., Iellamo, F., Lucini, D., Cerchiello, M., Castrucci, F., Pizzinelli, P., Porta, A., Malliani, A., 2001. Selective impairment of excitatory pressor responses after prolonged simulated microgravity in humans. Auton. Neurosci. 91, 85-95.
16. Smith, S.A., Mitchell, J.H., Garry, M.G., 2006. The mammalian exercise pressor reflex in health and disease. Exp. Physiol. 91, 89-102.
17. Spaak, J., Montmerle, S., Sundblad, P., Linnarsson, D., 2005. Long-term bed rest-induced reductions in stroke volume during rest and exercise: cardiac dysfunction vs. volume depletion. J. Appl. Physiol. 98, 648-654.
18. Spaak, J., Sundblad, P., Linnarsson, D., 2001. Impaired pressor response after spaceflight and bed rest: evidence for cardiovascular dysfunction. Eur. J. Appl. Physiol. 85, 49-55.
19. ten Harkel, A.D., Beck, L., Karemaker, J.M., 1992. Influence of posture and prolonged head-downtilt on cardiovascular reflexes. Acta Physiol. Scand. Suppl. 604, 77-87.