메뉴 건너뛰기




Volumn 13, Issue 12, 2009, Pages 1375-1386

Factors that retard remyelination in multiple sclerosis with a focus on TIP30: A novel therapeutic target

Author keywords

differentiation arrest; importin ; multiple sclerosis; nucleocytoplasmic transport; oligodendrocyte precursor cells; remyelination failure; TIP30

Indexed keywords

FC RECEPTOR; HYALURONIC ACID; JAGGED1; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; NERVE CELL ADHESION MOLECULE; NOTCH1 RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN; PROTEIN KINASE FYN; TAT INTERACTING PROTEIN 30; UNCLASSIFIED DRUG; ACYLTRANSFERASE; HTATIP2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 75349105353     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728220903307491     Document Type: Review
Times cited : (13)

References (107)
  • 1
    • 0028785251 scopus 로고
    • What the fly's glia tell the fly's brain
    • Pfrieger FW, Barres BA. What the fly's glia tell the fly's brain. Cell 1995;83:671-4
    • (1995) Cell , vol.83 , pp. 671-674
    • Pfrieger, F.W.1    Barres, B.A.2
  • 2
    • 33845907921 scopus 로고    scopus 로고
    • Rapid conduction and the evolution of giant Axons and myelinated fibers
    • DOI 10.1016/j.cub.2006.11.042, PII S0960982206025231
    • Hartline DK, Colman CR. Rapid conduction and the evolution of giant axons and myelinated fibers. Curr Biol 2007;17:R29-35 (Pubitemid 46027580)
    • (2007) Current Biology , vol.17 , Issue.1
    • Hartline, D.K.1    Colman, D.R.2
  • 3
    • 0001862032 scopus 로고
    • The myelogenetic cycles of regional maturation of the brain
    • Minkowski A editor Oxford: Blackwell
    • Yakovlev PL, Lecours AR. The myelogenetic cycles of regional maturation of the brain. In: Minkowski A, editor, Regional development of brain in early life. Oxford: Blackwell; 1967. p. 3-70
    • (1967) Regional Development of Brain in Early Life , pp. 3-70
    • Yakovlev, P.L.1    Lecours, A.R.2
  • 5
    • 4644340253 scopus 로고    scopus 로고
    • Maturation of white matter is associated with the development of cognitive functions during childhood
    • DOI 10.1162/0898929041920441
    • Nagy Z, Westerberg H, Klingberg T. Maturation of white matter is associated with the development of cognitive functions during childhood. J Cogn Neurosci 2004;16:1227-33 (Pubitemid 39274449)
    • (2004) Journal of Cognitive Neuroscience , vol.16 , Issue.7 , pp. 1227-1233
    • Nagy, Z.1    Westerberg, H.2    Klingberg, T.3
  • 6
    • 33750044086 scopus 로고    scopus 로고
    • White matter growth as a mechanism of cognitive development in children
    • DOI 10.1016/j.neuroimage.2006.07.024, PII S1053811906007865
    • Mabbott DJ, Noseworthy M, Bouffet E, et al. White matter growth as a mechanism of cognitive development in children. Neuroimage 2006;33:936-46 (Pubitemid 44584753)
    • (2006) NeuroImage , vol.33 , Issue.3 , pp. 936-946
    • Mabbott, D.J.1    Noseworthy, M.2    Bouffet, E.3    Laughlin, S.4    Rockel, C.5
  • 7
    • 67651036207 scopus 로고    scopus 로고
    • White matter integrity in the vicinity of Broca's area predicts grammar learning success
    • Flöel A, deVries MH, Scholz J, et al. White matter integrity in the vicinity of Broca's area predicts grammar learning success. Neuroimage 2009;47:1974-81
    • (2009) Neuroimage , vol.47 , pp. 1974-1981
    • Flöel, A.1    Devries, M.H.2    Scholz, J.3
  • 8
    • 27644458332 scopus 로고    scopus 로고
    • Extensive piano practicing has regionally specific effects on white matter development
    • DOI 10.1038/nn1516, PII N1516
    • Bengtsson SL, Nagy Z, Skare S, et al. Extensive piano practicing has regionally specific effects on white matter development. Nat Neurosci 2005;8:1148-50 (Pubitemid 43348132)
    • (2005) Nature Neuroscience , vol.8 , Issue.9 , pp. 1148-1150
    • Bengtsson, S.L.1    Nagy, Z.2    Skare, S.3    Forsman, L.4    Forssberg, H.5    Ullen, F.6
  • 9
    • 0035321573 scopus 로고    scopus 로고
    • The prevalence of multiple sclerosis in the world: An update
    • Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol Sci 2001;22:117-39 (Pubitemid 33771279)
    • (2001) Neurological Sciences , vol.22 , Issue.2 , pp. 117-139
    • Rosati, G.1
  • 11
    • 38349163681 scopus 로고    scopus 로고
    • Mortality in multiple sclerosis: A review
    • Ragonese P, Aridon P, Salemi G, et al. Mortality in multiple sclerosis: a review. Eur J Neurol 2008;15:123-7
    • (2008) Eur J Neurol , vol.15 , pp. 123-127
    • Ragonese, P.1    Aridon, P.2    Salemi, G.3
  • 12
    • 65249142200 scopus 로고    scopus 로고
    • The challenge of multiple sclerosis: How do we cure a chronic heterogeneous disease?
    • Weiner HL. The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease? Ann Neurol 2009;65:239-48
    • (2009) Ann Neurol , vol.65 , pp. 239-248
    • Weiner, H.L.1
  • 13
    • 64149102046 scopus 로고    scopus 로고
    • Recent clinical trials and future therapies
    • Meuth SG, Kleinschnitz C, Wiendl H. Recent clinical trials and future therapies. J Neurol 2008;255:93-6
    • (2008) J Neurol , vol.255 , pp. 93-96
    • Meuth, S.G.1    Kleinschnitz, C.2    Wiendl, H.3
  • 14
    • 66149146702 scopus 로고    scopus 로고
    • Extensive remyelination of the CNS leads to functional recovery
    • Duncan ID, Brower A, Kondo Y, et al. Extensive remyelination of the CNS leads to functional recovery. Proc Natl Acad Sci USA 2009;106:6832-6
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6832-6836
    • Duncan, I.D.1    Brower, A.2    Kondo, Y.3
  • 15
    • 0035060665 scopus 로고    scopus 로고
    • The oligodendrocyte precursor cell in health and disease
    • DOI 10.1016/S0166-2236(00)01691-X, PII S016622360001691X
    • Levine JM, Reynolds R, Fawcett JW. The oligodendrocyte precursor cell in health and disease. Trends Neurosci 2001;24:39-47 (Pubitemid 32332895)
    • (2001) Trends in Neurosciences , vol.24 , Issue.1 , pp. 39-47
    • Levine, J.M.1    Reynolds, R.2    Fawcett, J.W.3
  • 16
    • 17444367733 scopus 로고    scopus 로고
    • PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination
    • DOI 10.1016/j.nbd.2004.12.006
    • Murtie JC, Zhou YX, Le TQ, et al. PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination. Neurobiol Dis 2005;19:171-82 (Pubitemid 40544734)
    • (2005) Neurobiology of Disease , vol.19 , Issue.1-2 , pp. 171-182
    • Murtie, J.C.1    Zhou, Y.-X.2    Le, T.Q.3    Vana, A.C.4    Armstrong, R.C.5
  • 17
    • 0038692009 scopus 로고    scopus 로고
    • Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system
    • DOI 10.1093/brain/awg126
    • Penderis J, Shields SA, Franklin RJ. Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system. Brain 2003;126:1382-91 (Pubitemid 36644383)
    • (2003) Brain , vol.126 , Issue.6 , pp. 1382-1391
    • Penderis, J.1    Shields, S.A.2    Franklin, R.J.M.3
  • 18
    • 33748437057 scopus 로고    scopus 로고
    • Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS
    • DOI 10.1016/j.expneurol.2006.05.012, PII S0014488606002986
    • Li WW, Penderis J, Zhao C, et al. Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS. Exp Neurol 2006;202:250-4 (Pubitemid 44344247)
    • (2006) Experimental Neurology , vol.202 , Issue.1 , pp. 250-254
    • Li, W.-W.1    Penderis, J.2    Zhao, C.3    Schumacher, M.4    Franklin, R.J.M.5
  • 19
    • 50249167673 scopus 로고    scopus 로고
    • Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
    • Shen S, Sandoval J, Swiss VA, et al. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 2008;11:1024-34
    • (2008) Nat Neurosci , vol.11 , pp. 1024-1034
    • Shen, S.1    Sandoval, J.2    Swiss, V.A.3
  • 20
    • 54249124952 scopus 로고    scopus 로고
    • Remyelination in the CNS: From biology to therapy
    • Franklin RJ, Ffrench-Constant C. Remyelination in the CNS: from biology to therapy. Nat Rev Neurosci 2008;9:839-55
    • (2008) Nat Rev Neurosci , vol.9 , pp. 839-855
    • Franklin, R.J.1    Ffrench-Constant, C.2
  • 22
    • 67650079567 scopus 로고    scopus 로고
    • Remyelination capacity of the MS brain decreases with disease chronicity
    • Goldschmidt T, Antel J, König FB, et al. Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 2009;72:1914-21
    • (2009) Neurology , vol.72 , pp. 1914-1921
    • Goldschmidt, T.1    Antel, J.2    König, F.B.3
  • 23
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • Trapp BD, Nave KA. Multiple sclerosis: an immune or neurodegenerative disorder? Ann Rev Neurosci 2008;31:247-69
    • (2008) Ann Rev Neurosci , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.A.2
  • 24
    • 33845329201 scopus 로고    scopus 로고
    • Axonal protection in multiple sclerosis - A particular need during remyelination?
    • DOI 10.1093/brain/awl323
    • Smith KJ. Axonal protection in multiple sclerosis-a particular need during remyelination? Brain 2006;129:3147-9 (Pubitemid 44871431)
    • (2006) Brain , vol.129 , Issue.12 , pp. 3147-3149
    • Smith, K.J.1
  • 26
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • Franklin RJM. Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci 2002;3:705-14
    • (2002) Nat Rev Neurosci , vol.3 , pp. 705-714
    • Rjm, F.1
  • 27
    • 0028578038 scopus 로고
    • Patterns of oligodendroglia pathology in multiple sclerosis
    • Ozawa K, Suchanek G, Breitschopf H, et al. Patterns of oligodendroglia pathology in multiple sclerosis. Brain 1994;117:1311-22
    • (1994) Brain , vol.117 , pp. 1311-1322
    • Ozawa, K.1    Suchanek, G.2    Breitschopf, H.3
  • 28
    • 0025986056 scopus 로고
    • Remyelination of demyelinated rat axons by transplanted mouse oligodendrocytes
    • Crang AJ, Blakemore WF. Remyelination of demyelinated rat axons by transplanted mouse oligodendrocytes. Glia 1991;4:305-13
    • (1991) Glia , vol.4 , pp. 305-313
    • Crang, A.J.1    Blakemore, W.F.2
  • 30
    • 0017580782 scopus 로고
    • Remyelination of CNS axons by Schwann cells transplanted from the sciatic nerve
    • Blakemore WF. Remyelination of CNS axons by Schwann cells transplanted from the sciatic nerve. Nature 1977;266:68-9 (Pubitemid 8050019)
    • (1977) Nature , vol.266 , Issue.5597 , pp. 68-69
    • Blakemore, W.F.1
  • 31
    • 0031962240 scopus 로고    scopus 로고
    • Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
    • Wolswijk G. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci 1998;18:601-9 (Pubitemid 28041896)
    • (1998) Journal of Neuroscience , vol.18 , Issue.2 , pp. 601-609
    • Wolswijk, G.1
  • 32
    • 0031797815 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis
    • Scolding N, Franklin R, Stevens S, et al. Oligodendrocyte progenitors are present in normal adult human CNS and in the lesions of multiple sclerosis. Brain 1998;121:2221-8 (Pubitemid 28552461)
    • (1998) Brain , vol.121 , Issue.12 , pp. 2221-2228
    • Scolding, N.1    Franklin, R.2    Stevens, S.3    Heldin, C.-H.4    Compston, A.5    Newcombe, J.6
  • 33
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
    • Chang A, Nishiyama A, Peterson J, et al. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci 2000;20:6404-12
    • (2000) J Neurosci , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3
  • 36
    • 46849098585 scopus 로고    scopus 로고
    • Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
    • DOI 10.1093/brain/awn096
    • Kuhlmann T, Miron V, Cuo Q, et al. Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 2008;131:1749-58 (Pubitemid 351957453)
    • (2008) Brain , vol.131 , Issue.7 , pp. 1749-1758
    • Kuhlmann, T.1    Miron, V.2    Cuo, Q.3    Wegner, C.4    Antel, J.5    Bruck, W.6
  • 37
    • 33746763888 scopus 로고    scopus 로고
    • Fc receptor-positive cells in remyelinating multiple sclerosis lesions
    • PII 0000507220060600000006
    • Nakahara J, Aiso S. Fc receptor-positive cells in remyelinating multiple sclerosis lesions. J Neuropathol Appl Neurol 2006;65:582-91 (Pubitemid 44288942)
    • (2006) Journal of Neuropathology and Experimental Neurology , vol.65 , Issue.6 , pp. 582-591
    • Nakahara, J.1    Aiso, S.2
  • 38
    • 0037122960 scopus 로고    scopus 로고
    • Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
    • DOI 10.1056/NEJMoa010994
    • Chang A, Tourtellotte WW, Rudick R, Trapp BD. Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 2002;346:165-73 (Pubitemid 34438882)
    • (2002) New England Journal of Medicine , vol.346 , Issue.3 , pp. 165-173
    • Chang, A.1    Tourtellotte, W.W.2    Rudick, R.3    Trapp, B.D.4
  • 40
    • 0036723599 scopus 로고    scopus 로고
    • Re-expression of PSA-NCAM by demyelinated axons: An inhibitor of remyelination in multiple sclerosis?
    • Charles P, Reynolds R, Seilhean D, et al. Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis? Brain 2002;125:1972-9
    • (2002) Brain , vol.125 , pp. 1972-1979
    • Charles, P.1    Reynolds, R.2    Seilhean, D.3
  • 42
    • 4344625746 scopus 로고    scopus 로고
    • Notch1 and jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination
    • DOI 10.1093/brain/awh217
    • Stidworthy MF, Genoud S, Li WW, et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 2004;127:1928-41 (Pubitemid 39150252)
    • (2004) Brain , vol.127 , Issue.9 , pp. 1928-1941
    • Stidworthy, M.F.1    Genoud, S.2    Li, W.-W.3    Leone, D.P.4    Mantei, N.5    Suter, U.6    Franklin, R.J.M.7
  • 44
    • 61749099508 scopus 로고    scopus 로고
    • Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis
    • Nakahara J, Kanekura K, Nawa M, et al. Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis. J Clin Invest 2009;119:169-81
    • (2009) J Clin Invest , vol.119 , pp. 169-181
    • Nakahara, J.1    Kanekura, K.2    Nawa, M.3
  • 46
    • 0027976632 scopus 로고
    • Initial events of myelination involve Fyn tyrosine kinase signalling
    • DOI 10.1038/367572a0
    • Umemori H, Sato S, Yagi T, et al. Initial events of myelination involve Fyn tyrosine kinase signaling. Nature 1994;367:572-6 (Pubitemid 24055518)
    • (1994) Nature , vol.367 , Issue.6463 , pp. 572-576
    • Umemori, H.1    Sato, S.2    Yagi, T.3    Aizawa, S.4    Yamamoto, T.5
  • 47
    • 4143050338 scopus 로고    scopus 로고
    • Signaling from integrins to Fyn to Rho family GTPases regulates morphologic differentiation of oligodendrocytes
    • DOI 10.1523/JNEUROSCI.5319-03.2004
    • Liang X, Draghi NA, Resh MD. Signaling from integrins to Fyn to Rho family GTPases regulates morphologic differentiation of oligodendrocytes. J Neurosci 2004;24:7140-9 (Pubitemid 39096379)
    • (2004) Journal of Neuroscience , vol.24 , Issue.32 , pp. 7140-7149
    • Liang, X.1    Draghi, N.A.2    Resh, M.D.3
  • 49
    • 65249142739 scopus 로고    scopus 로고
    • Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
    • Mi S, Miller RH, Tang W, et al. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Ann Neurol 2009;65:304-15
    • (2009) Ann Neurol , vol.65 , pp. 304-315
    • Mi, S.1    Miller, R.H.2    Tang, W.3
  • 50
    • 33846148013 scopus 로고    scopus 로고
    • TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions
    • DOI 10.1111/j.1365-2990.2006.00787.x
    • Satoh J, Tabunoki H, Yamamura T, et al. TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions. Neuropathol Appl Neurobiol 2007;33:99-107 (Pubitemid 46090314)
    • (2007) Neuropathology and Applied Neurobiology , vol.33 , Issue.1 , pp. 99-107
    • Satoh, J.1    Tabunoki, H.2    Yamamura, T.3    Arima, K.4    Konno, H.5
  • 51
    • 30644476095 scopus 로고    scopus 로고
    • Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
    • DOI 10.1523/JNEUROSCI.2615-05.2006
    • Kotter MR, Li WW, Zhao C, Franklin RJ. Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation. J Neurosci 2006;26:328-32 (Pubitemid 43089546)
    • (2006) Journal of Neuroscience , vol.26 , Issue.1 , pp. 328-332
    • Kotter, M.R.1    Li, W.-W.2    Zhao, C.3    Franklin, R.J.M.4
  • 52
    • 67649655942 scopus 로고    scopus 로고
    • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
    • Fancy SPJ, Baranzini SE, Zhao C, et al. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev 2009;23:1571-85
    • (2009) Genes Dev , vol.23 , pp. 1571-1585
    • Spj, F.1    Baranzini, S.E.2    Zhao, C.3
  • 53
    • 15044357461 scopus 로고    scopus 로고
    • Inflammation stimulates remyelination in areas of chronic demyelination
    • DOI 10.1093/brain/awh417
    • Foote AK, Blakemore WF. Inflammation stimulates remyelination in areas of chronic demyelination. Brain 2005;128:528-39 (Pubitemid 40380188)
    • (2005) Brain , vol.128 , Issue.3 , pp. 528-539
    • Foote, A.K.1    Blakemore, W.F.2
  • 55
    • 33646251131 scopus 로고    scopus 로고
    • Innate immunity triggers oligodendrocyte progenitor reactivity and confines damages to brain injuries
    • DOI 10.1096/fj.05-5234fje
    • Glezer I, Lapointe A, Rivest S. Innate immunity triggers oligodendrocyte progenitor reactivity and confines damage to brain injuries. FASEB J 2006;20:750-2 (Pubitemid 46671203)
    • (2006) FASEB Journal , vol.20 , Issue.6 , pp. 750-752
    • Glezer, I.1    Lapointe, A.2    Rivest, S.3
  • 56
    • 67650084311 scopus 로고    scopus 로고
    • Endogenous remyelination is induced by transplant rejection in a viral model of multiple sclerosis
    • Hatch MN, Schaumburg CS, Lane TE, Keirstead HS. Endogenous remyelination is induced by transplant rejection in a viral model of multiple sclerosis. J Neuroimmunol 2009:212(1-2):74-81
    • (2009) J Neuroimmunol , vol.212 , Issue.1-2 , pp. 74-81
    • Hatch, M.N.1    Schaumburg, C.S.2    Lane, T.E.3    Keirstead, H.S.4
  • 57
    • 34247862406 scopus 로고    scopus 로고
    • Remyelination can be extensive in multiple sclerosis despite a long disease course
    • DOI 10.1111/j.1365-2990.2007.00805.x
    • Patani R, Balaratnam M, Vora A, Reynolds A. Remyelination can be extensive in multiple sclerosis despite a long disease course. Neuropathol Appl Neurobiol 2007;33:277-87 (Pubitemid 46701044)
    • (2007) Neuropathology and Applied Neurobiology , vol.33 , Issue.3 , pp. 277-287
    • Patani, R.1    Balaratnam, M.2    Vora, A.3    Reynolds, R.4
  • 58
    • 48349089936 scopus 로고    scopus 로고
    • CCR5 expression on macrophages/microglia is associated with early remyelination in multiple sclerosis lesions
    • Trebst C, König F, Ransohoff R, et al. CCR5 expression on macrophages/microglia is associated with early remyelination in multiple sclerosis lesions. Mult Scler 2008;14:728-33
    • (2008) Mult Scler , vol.14 , pp. 728-733
    • Trebst, C.1    König, F.2    Ransohoff, R.3
  • 59
    • 0033946875 scopus 로고    scopus 로고
    • Steroids for multiple sclerosis and optic neuritis: A meta-analysis of randomized controlled clinical trials
    • DOI 10.1007/s004150070172
    • Brusaferri F, Candelise L. Steroids for multiple sclerosis and optic neuritis: a meta-analysis of randomized controlled clinical trials. J Neurol 2000;247:435-42 (Pubitemid 30433557)
    • (2000) Journal of Neurology , vol.247 , Issue.6 , pp. 435-442
    • Brusaferri, F.1    Candelise, L.2
  • 61
    • 44149117017 scopus 로고    scopus 로고
    • Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules
    • DOI 10.1083/jcb.200706164
    • White R, Gonsior C, Krämer-Albers EM, et al. Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules. J Cell Biol 2008;181:579-86 (Pubitemid 351717505)
    • (2008) Journal of Cell Biology , vol.181 , Issue.4 , pp. 579-586
    • White, R.1    Gonsior, C.2    Kramer-Albers, E.-M.3    Stohr, N.4    Huttelmaier, S.5    Trotter, J.6
  • 62
    • 0033553885 scopus 로고    scopus 로고
    • Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase
    • DOI 10.1083/jcb.145.6.1209
    • Osterhout DJ, Wolven A, Wolf RM, et al. Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase. J Cell Biol 1999;145:1209-18 (Pubitemid 29293633)
    • (1999) Journal of Cell Biology , vol.145 , Issue.6 , pp. 1209-1218
    • Osterhout, D.J.1    Wolven, A.2    Wolf, R.M.3    Resh, M.D.4    Chao, M.V.5
  • 63
    • 0036469248 scopus 로고    scopus 로고
    • Process outgrowth of oligodendrocytes is promoted by interaction of Fyn kinase with the cytoskeletal protein Tau
    • Klein C, Kramer EM, Cardine AM, et al. Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau. J Neurosci 2002;22:698-707 (Pubitemid 34141750)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 698-707
    • Klein, C.1    Kramer, E.-M.2    Cardine, A.-M.3    Schraven, B.4    Brandt, R.5    Trotter, J.6
  • 64
    • 53149103944 scopus 로고    scopus 로고
    • Truncated Tau with the Fyn-biding domain and without the microtubule-binding domain hinders the myelinating capacity of an oligodendrocyte cell line
    • Belkadi A, LoPresti P. Truncated Tau with the Fyn-biding domain and without the microtubule-binding domain hinders the myelinating capacity of an oligodendrocyte cell line. J Neurochem 2008;107:351-60
    • (2008) J Neurochem , vol.107 , pp. 351-360
    • Belkadi, A.1    Lopresti, P.2
  • 65
    • 0034858207 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation
    • Wolf RM, Wilkes JJ, Chao MV, Resh MD. Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation. J Neurobiol 2001;49:62-78
    • (2001) J Neurobiol , vol.49 , pp. 62-78
    • Wolf, R.M.1    Wilkes, J.J.2    Chao, M.V.3    Resh, M.D.4
  • 66
    • 14844282064 scopus 로고    scopus 로고
    • Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven
    • DOI 10.1111/j.1471-4159.2004.02946.x
    • Jiang S, Avraham HK, Park SY, et al. Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven. J Neurochem 2005;92:1191-203 (Pubitemid 40344309)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.5 , pp. 1191-1203
    • Jiang, S.1    Avraham, H.K.2    Park, S.-Y.3    Kim, T.-A.4    Bu, X.5    Seng, S.6    Avraham, S.7
  • 67
    • 35748968479 scopus 로고    scopus 로고
    • Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth
    • DOI 10.1111/j.1365-2443.2007.01130.x
    • Hoshina N, Tezuka T, Yokoyama K, et al. Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth. Genes Cells 2007;12:1245-54 (Pubitemid 350042422)
    • (2007) Genes to Cells , vol.12 , Issue.11 , pp. 1245-1254
    • Hoshina, N.1    Tezuka, T.2    Yokoyama, K.3    Kozuka-hata, H.4    Oyama, M.5    Yamamoto, T.6
  • 68
    • 51149123070 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn
    • Miyamoto Y, Yamauchi J, Tanoue A. Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn. J Neurosci 2008;28:8326-37
    • (2008) J Neurosci , vol.28 , pp. 8326-8337
    • Miyamoto, Y.1    Yamauchi, J.2    Tanoue, A.3
  • 69
    • 7244247059 scopus 로고    scopus 로고
    • Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development
    • DOI 10.1083/jcb.200404076
    • Colognato H, Ramachandrappa S, Olsen IM, Ffrench-Constant C. Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development. J Cell Biol 2004;167:365-75 (Pubitemid 39435078)
    • (2004) Journal of Cell Biology , vol.167 , Issue.2 , pp. 365-375
    • Colognato, H.1    Ramachandrappa, S.2    Olsen, I.M.3    Ffrench-Constant, C.4
  • 70
    • 60149094000 scopus 로고    scopus 로고
    • Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signaling
    • Baer AS, Syed YA, Kang SU, et al. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signaling. Brain 2009;132:465-81
    • (2009) Brain , vol.132 , pp. 465-481
    • Baer, A.S.1    Syed, Y.A.2    Kang, S.U.3
  • 71
    • 0038933866 scopus 로고    scopus 로고
    • Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination
    • Krämer EM, Klein C, Koch T, et al. Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination. J Biol Chem 1999;274:29042-9
    • (1999) J Biol Chem , vol.274 , pp. 29042-29049
    • Krämer, E.M.1    Klein, C.2    Koch, T.3
  • 73
    • 15744389880 scopus 로고    scopus 로고
    • Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival
    • DOI 10.1074/jbc.M414267200
    • Cui QL, Zheng WH, Quirion R, Almazan G. Inhibition of Src-like kinases reveals Akt-dependent and-independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival. J Biol Chem 2005;280:8918-28 (Pubitemid 40409583)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 8918-8928
    • Cui, Q.-L.1    Zheng, W.-H.2    Quirion, R.3    Almazan, G.4
  • 74
    • 33644643568 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways
    • DOI 10.1016/j.neuint.2005.11.014, PII S0197018605002883
    • Cui QL, Fogle E, Almazan G. Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways. Neurochem Int 2006;48:383-93 (Pubitemid 43327278)
    • (2006) Neurochemistry International , vol.48 , Issue.5 , pp. 383-393
    • Cui, Q.-L.1    Fogle, E.2    Almazan, G.3
  • 75
    • 64549099929 scopus 로고    scopus 로고
    • Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA
    • Rajasekharan S, Baker KA, Horn KE, et al. Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA. Development 2009;136:415-26
    • (2009) Development , vol.136 , pp. 415-426
    • Rajasekharan, S.1    Baker, K.A.2    Horn, K.E.3
  • 77
    • 0042830859 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Taking an inventory
    • DOI 10.1007/s00018-003-3070-3
    • Fried H, Kutay U. Nucleocytoplasmic transport: taking an inventory. Cell Mol Life Sci 2003;60:1659-88 (Pubitemid 37041364)
    • (2003) Cellular and Molecular Life Sciences , vol.60 , Issue.8 , pp. 1659-1688
    • Fried, H.1    Kutay, U.2
  • 78
    • 0030996563 scopus 로고    scopus 로고
    • A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma
    • Shtivelman E. A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma. Oncogene 1997;14:2167-73 (Pubitemid 27248228)
    • (1997) Oncogene , vol.14 , Issue.18 , pp. 2167-2173
    • Shtivelman, E.1
  • 79
    • 0032478173 scopus 로고    scopus 로고
    • A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription
    • Xiao H, Tao Y, Greenblatt J, Roeder RG. A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription. Proc Natl Acad Sci USA 1998;95:2146-51
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2146-2151
    • Xiao, H.1    Tao, Y.2    Greenblatt, J.3    Roeder, R.G.4
  • 81
    • 34248589591 scopus 로고    scopus 로고
    • TIP30 mutant derived from hepatocellular carcinoma specimens promotes growth of HepG2 cells through up-regulation of N-cadherin
    • DOI 10.1158/0008-5472.CAN-06-0831
    • Jiang C, Pecha J, Hoshino I, et al. TIP30 mutant derived from hepatocellular carcinoma specimens promotes growth of HepG2 cells through up-regulation of N-cadherin. Cancer Res 2007;67:3574-82 (Pubitemid 46762141)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3574-3582
    • Jiang, C.1    Pecha, J.2    Hoshino, I.3    Ankrapp, D.4    Xiao, H.5
  • 82
    • 36348986135 scopus 로고    scopus 로고
    • Deletion of Tip30 leads to rapid immortalization of murine mammary epithelial cells and ductal hyperplasia in the mammary gland
    • DOI 10.1038/sj.onc.1210548, PII 1210548
    • Pecha J, Ankrapp D, Jiang C, et al. Deletion of Tip30 leads to rapid immortalization of murine mammary epithelial cells and ductal hyperplasia in the mammary gland. Oncogene 2007;26:7423-31 (Pubitemid 350158711)
    • (2007) Oncogene , vol.26 , Issue.53 , pp. 7423-7431
    • Pecha, J.1    Ankrapp, D.2    Jiang, C.3    Tang, W.4    Hoshino, I.5    Bruck, K.6    Wagner, K.-U.7    Xiao, H.8
  • 83
    • 33846226109 scopus 로고    scopus 로고
    • TIP30/CC3 expression in breast carcinoma: relation to metastasis, clinicopathologic parameters, and P53 expression
    • DOI 10.1016/j.humpath.2006.08.005, PII S0046817706004965
    • Zhao J, Ni H, Ma Y, et al. TIP30/CC3 expression in breast carcinoma: relation to metastasis, clinicopathologic parameters, and p53 expression. Human Pathol 2007;38:293-8 (Pubitemid 46096554)
    • (2007) Human Pathology , vol.38 , Issue.2 , pp. 293-298
    • Zhao, J.1    Ni, H.2    Ma, Y.3    Dong, L.4    Dai, J.5    Zhao, F.6    Yan, X.7    Lu, B.8    Xu, H.9    Guo, Y.10
  • 84
    • 58149279842 scopus 로고    scopus 로고
    • Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis
    • Li X, Zhang Y, Cao S, et al. Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis. Int J Cancer 2009;124:713-21
    • (2009) Int J Cancer , vol.124 , pp. 713-721
    • Li, X.1    Zhang, Y.2    Cao, S.3
  • 85
    • 65649139137 scopus 로고    scopus 로고
    • Decreased TIP30 expression promotes tumor metastasis in lung cancer
    • Tong X, Li K, Luo Z, et al. Decreased TIP30 expression promotes tumor metastasis in lung cancer. Am J Pathol 2009;174:1931-9
    • (2009) Am J Pathol , vol.174 , pp. 1931-1939
    • Tong, X.1    Li, K.2    Luo, Z.3
  • 87
    • 3042688442 scopus 로고    scopus 로고
    • TIP30 interacts with an estrogen receptor α-interacting coactivator CIA and regulates c-myc transcription
    • DOI 10.1074/jbc.M401809200
    • Jiang C, Ito M, Piening V, et al. TIP30 interacts with an estrogen receptor a-interacting coactivator CIA and regulates c-myc transcription. J Biol Chem 2004;279:27781-9 (Pubitemid 38812620)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.26 , pp. 27781-27789
    • Jiang, C.1    Ito, M.2    Piening, V.3    Bruck, K.4    Roeder, R.G.5    Xiao, H.6
  • 88
    • 47149089187 scopus 로고    scopus 로고
    • Thirty-kilodalton tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma
    • DOI 10.1002/hep.22280
    • Zhao J, Lu B, Xu H, et al. Thirty-kilodalton Tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma. Hepatology 2008;48:265-75 (Pubitemid 351975551)
    • (2008) Hepatology , vol.48 , Issue.1 , pp. 265-275
    • Zhao, J.1    Lu, B.2    Xu, H.3    Tong, X.4    Wu, G.5    Zhang, X.6    Liang, A.7    Cong, W.8    Dai, J.9    Wang, H.10    Wu, M.11    Guo, Y.12
  • 89
    • 49249118307 scopus 로고    scopus 로고
    • TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma
    • Zhao J, Chen J, Lu B, et al. TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma. Cancer Res 2008;68:4133-41
    • (2008) Cancer Res , vol.68 , pp. 4133-4141
    • Zhao, J.1    Chen, J.2    Lu, B.3
  • 91
    • 38349057750 scopus 로고    scopus 로고
    • Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells
    • Shi M, Yan SG, Xie ST, Wang HN. Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells. Biochem Biophys Acta 2008;1783:263-74
    • (2008) Biochem Biophys Acta , vol.1783 , pp. 263-274
    • Shi, M.1    Yan, S.G.2    Xie, S.T.3    Wang, H.N.4
  • 92
    • 0035843152 scopus 로고    scopus 로고
    • Metastasis suppressor CC3 inhibits augiogenic properties of tumor cells in vitro
    • DOI 10.1038/sj.onc.1204075
    • NicAmhlaoibh R, Shtivelman E. Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro. Oncogene 2001;20:270-5 (Pubitemid 32150272)
    • (2001) Oncogene , vol.20 , Issue.2 , pp. 270-275
    • NicAmhlaoibh, R.1    Shtivelman, E.2
  • 93
    • 0034161272 scopus 로고    scopus 로고
    • TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes
    • Xiao H, Palhan V, Yang Y, Roeder RG. TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes. EMBO J 2000;19:956-63 (Pubitemid 30119821)
    • (2000) EMBO Journal , vol.19 , Issue.5 , pp. 956-963
    • Xiao, H.1    Palhan, V.2    Yang, Y.3    Roeder, R.G.4
  • 94
    • 0033166792 scopus 로고    scopus 로고
    • TIP30, a cofactor for HIV-1 Tat-activated transcription, is homologous to short-chain dehydrogenases/reductases [2]
    • DOI 10.1016/S0960-9822(99)80297-8
    • Baker ME. TIP30, a cofactor for HIV-1 Tat-activated transcription is homologous to short-chain dehydrogenases/reductases. Curr Biol 1999;9:R471 (Pubitemid 29332338)
    • (1999) Current Biology , vol.9 , Issue.13
    • Baker, M.E.1
  • 95
    • 0034045656 scopus 로고    scopus 로고
    • Three-dimensional model of human TIP30, a coactivator for HIV-1 Tat-activated transcription, and CC3, a protein associated with metastasis suppression
    • DOI 10.1007/s000180050047
    • Baker ME, Yan L, Pear MR. Three-dimentional model of human TIP30, a coactivator for HIV-1 Tat-activated transcription, and CC3, a protein associated with metastasis suppression. Cell Mol Life Sci 2000;57:851-8 (Pubitemid 30392041)
    • (2000) Cellular and Molecular Life Sciences , vol.57 , Issue.5 , pp. 851-858
    • Baker, M.E.1    Yan, L.2    Pear, M.R.3
  • 96
    • 24044467412 scopus 로고    scopus 로고
    • Crystal structure of CC3 (TIP30)
    • Omari KE, Bird LE, Nichols CE, et al. Crystal structure of CC3 (TIP30). J Biol Chem 2005;280:18229-36
    • (2005) J Biol Chem , vol.280 , pp. 18229-18236
    • Omari, K.E.1    Bird, L.E.2    Nichols, C.E.3
  • 97
    • 3542992061 scopus 로고    scopus 로고
    • Inhibition of nuclear import by the proapoptotic protein CC3
    • DOI 10.1128/MCB.24.16.7091-7101.2004
    • King FW, Shtivelman E. Inhibition of nuclear import by the proapoptotic protein CC3. Mol Cell Biol 2004;24:7091-101 (Pubitemid 39014436)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.16 , pp. 7091-7101
    • King, F.W.1    Shtivelman, E.2
  • 99
    • 0037721736 scopus 로고    scopus 로고
    • Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle
    • DOI 10.1016/S0304-3835(03)00154-X
    • Chaudhry MA, Chodosh LA, McKenna WG, Muschel RJ. Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycle. Cancer Lett 2003;195:221-33 (Pubitemid 36588971)
    • (2003) Cancer Letters , vol.195 , Issue.2 , pp. 221-233
    • Chaudhry, M.A.1    Chodosh, L.A.2    McKenna, W.G.3    Muschel, R.J.4
  • 100
    • 1542344026 scopus 로고    scopus 로고
    • The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells
    • DOI 10.1091/mbc.E03-10-0742
    • Lesur I, Campbell JL. The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells. Mol Biol Cell 2004;15:1297-312 (Pubitemid 38316236)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.3 , pp. 1297-1312
    • Lesur, I.1    Campbell, J.L.2
  • 101
    • 0035838951 scopus 로고    scopus 로고
    • Differentially expressed CC3/TIP30 and rab11 along in vivo and in vitro intestinal epithelial cell crypt-villus axis
    • DOI 10.1016/S0024-3205(01)01216-4, PII S0024320501012164
    • Lindfors K, Halttunen T, Kainulainen H, Mäki M. Differentially expressed CC3/TIP30 and rab11 along in vivo and in vitro intestinal epithelial cell crypt-villus axis. Life Sci 2001;69:1363-72 (Pubitemid 32758704)
    • (2001) Life Sciences , vol.69 , Issue.12 , pp. 1363-1372
    • Lindfors, K.1    Halttunen, T.2    Kainulainen, H.3    Maki, M.4
  • 102
    • 72749114767 scopus 로고    scopus 로고
    • Activation of prometastatic gene expression program in hypoxic neuroblastoma cells
    • Poomthavorn P, Wong S, Higgins S, et al. Activation of prometastatic gene expression program in hypoxic neuroblastoma cells. Endocr Relat Cancer 2009:16(3):991-1004
    • (2009) Endocr Relat Cancer , vol.16 , Issue.3 , pp. 991-1004
    • Poomthavorn, P.1    Wong, S.2    Higgins, S.3
  • 103
    • 58149330690 scopus 로고    scopus 로고
    • Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma
    • Lu B, Ma Y, Wu G, et al. Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma. Clin Cancer Res 2008;14:7405-12
    • (2008) Clin Cancer Res , vol.14 , pp. 7405-7412
    • Lu, B.1    Ma, Y.2    Wu, G.3
  • 104
    • 33750288443 scopus 로고    scopus 로고
    • Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis
    • DOI 10.1007/s00401-006-0130-4
    • Zhang J, Ito H, Wate R, et al. Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Acta Neuropathol 2006;112:673-80 (Pubitemid 44615028)
    • (2006) Acta Neuropathologica , vol.112 , Issue.6 , pp. 673-680
    • Zhang, J.1    Ito, H.2    Wate, R.3    Ohnishi, S.4    Nakano, S.5    Kusaka, H.6
  • 106
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • DOI 10.1002/ana.20016
    • Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion. Ann Neurol 2004;55:458-68 (Pubitemid 38391962)
    • (2004) Annals of Neurology , vol.55 , Issue.4 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.