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Volumn 48, Issue 3, 2010, Pages 332-336

Practical and functional culture technologies for primary hepatocytes

Author keywords

Animal cell culture; Biomedical; Bioreactor; Hepatocyte; Immobilization; Liver tissue engineering

Indexed keywords

ARGININE-GLYCINE-ASPARTIC ACIDS; BLOOD PURIFICATION; CELL MATRIX INTERACTIONS; CULTURE METHODS; CULTURE SYSTEMS; DRUG METABOLISMS; EXTRACELLULAR MATRICES; HEPATOCYTE; HEPATOCYTE CULTURE; HEPATOCYTES; IMMOBILIZED CULTURE; LIVER TISSUE ENGINEERING; LIVER-SPECIFIC FUNCTIONS; MACROPOROUS; PRIMARY HEPATOCYTES; RAT HEPATOCYTES;

EID: 75349100577     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2009.10.003     Document Type: Review
Times cited : (16)

References (33)
  • 1
    • 0025135443 scopus 로고
    • Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments
    • Koide N., Sakaguchi K., Koide Y., Asano K., Kawaguchi M., Matsushima H., Takenami T., Shinji T., Mori M., and Tsuji T. Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments. Exp. Cell Res. 186 (1990) 227-235
    • (1990) Exp. Cell Res. , vol.186 , pp. 227-235
    • Koide, N.1    Sakaguchi, K.2    Koide, Y.3    Asano, K.4    Kawaguchi, M.5    Matsushima, H.6    Takenami, T.7    Shinji, T.8    Mori, M.9    Tsuji, T.10
  • 2
    • 1842556200 scopus 로고    scopus 로고
    • Development of co-culture system of hepatocytes with bone marrow cells for expression and maintenance of hepatic functions
    • Murakami S., Ijima H., Ono T., and Kawakami K. Development of co-culture system of hepatocytes with bone marrow cells for expression and maintenance of hepatic functions. Int. J. Artif. Organs 27 (2004) 118-126
    • (2004) Int. J. Artif. Organs , vol.27 , pp. 118-126
    • Murakami, S.1    Ijima, H.2    Ono, T.3    Kawakami, K.4
  • 4
    • 0024502767 scopus 로고
    • Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration
    • Dunn J.C.Y., Yarmush M.L., Koebe H.G., and Tompkins R. Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J. 3 (1989) 174-177
    • (1989) FASEB J. , vol.3 , pp. 174-177
    • Dunn, J.C.Y.1    Yarmush, M.L.2    Koebe, H.G.3    Tompkins, R.4
  • 6
    • 0022982255 scopus 로고
    • Long-term maintenance of hepatocyte functional activity in co-culture: requirements for sinusoidal endothelial cells and dexamethasone
    • Morin O., and Normand C. Long-term maintenance of hepatocyte functional activity in co-culture: requirements for sinusoidal endothelial cells and dexamethasone. J. Cell Physiol. 129 (1986) 103-110
    • (1986) J. Cell Physiol. , vol.129 , pp. 103-110
    • Morin, O.1    Normand, C.2
  • 8
    • 0030967335 scopus 로고    scopus 로고
    • Prolonged lidocaine metabolizing activity of primary hepatocytes with spheroid culture using polyurethane foam as a culture substratum
    • Nakazawa K., Matsushita T., and Funatsu K. Prolonged lidocaine metabolizing activity of primary hepatocytes with spheroid culture using polyurethane foam as a culture substratum. Cytotechnology 24 (1997) 235-242
    • (1997) Cytotechnology , vol.24 , pp. 235-242
    • Nakazawa, K.1    Matsushita, T.2    Funatsu, K.3
  • 9
    • 0026069665 scopus 로고
    • High albumin production by multicellular spheroids of adult-rat hepatocytes formed in the pores of polyurethane foam
    • Matsushita T., Ijima H., Koide N., and Funatsu K. High albumin production by multicellular spheroids of adult-rat hepatocytes formed in the pores of polyurethane foam. Appl. Microbiol. Biotechnol. 36 (1991) 324-326
    • (1991) Appl. Microbiol. Biotechnol. , vol.36 , pp. 324-326
    • Matsushita, T.1    Ijima, H.2    Koide, N.3    Funatsu, K.4
  • 10
    • 0031850602 scopus 로고    scopus 로고
    • Formation of a spherical multicellular aggregate (spheroid) of animal cells in the pores of polyurethane foam as a cell culture substratum and its application to a hybrid artificial liver
    • Ijima H., Nakazawa K., Mizumoto H., Matsushita T., and Funatsu K. Formation of a spherical multicellular aggregate (spheroid) of animal cells in the pores of polyurethane foam as a cell culture substratum and its application to a hybrid artificial liver. J. Biomater. Sci. Polym. Ed. 9 (1998) 765-778
    • (1998) J. Biomater. Sci. Polym. Ed. , vol.9 , pp. 765-778
    • Ijima, H.1    Nakazawa, K.2    Mizumoto, H.3    Matsushita, T.4    Funatsu, K.5
  • 11
    • 0026769067 scopus 로고
    • Switching from differentiation of growth in hepatocytes: control by extracellular matrix
    • Mooney D., Hansen L., Vacanti J., Langer R., Farmer S., and Ingber D. Switching from differentiation of growth in hepatocytes: control by extracellular matrix. J. Cell. Phys. 151 (1992) 497-505
    • (1992) J. Cell. Phys. , vol.151 , pp. 497-505
    • Mooney, D.1    Hansen, L.2    Vacanti, J.3    Langer, R.4    Farmer, S.5    Ingber, D.6
  • 12
    • 0001377079 scopus 로고
    • Induction of hepatocyte differentiation by the extracellular matrix and an RGD-containing synthetic peptide
    • Mooney D.J., and Langer R. Induction of hepatocyte differentiation by the extracellular matrix and an RGD-containing synthetic peptide. Mater. Res. Soc. Symp. Proc. 252 (1992) 199-204
    • (1992) Mater. Res. Soc. Symp. Proc. , vol.252 , pp. 199-204
    • Mooney, D.J.1    Langer, R.2
  • 13
    • 0033992251 scopus 로고    scopus 로고
    • Hepatocyte adhesion, growth and differentiated function on RGD-containing proteins
    • Bhadriraju K., and Hansen L.K. Hepatocyte adhesion, growth and differentiated function on RGD-containing proteins. Biomaterials 21 (2000) 267-272
    • (2000) Biomaterials , vol.21 , pp. 267-272
    • Bhadriraju, K.1    Hansen, L.K.2
  • 14
    • 27644579559 scopus 로고    scopus 로고
    • Promote a monolayer formation and highly express the ammonia metabolism of primary rat hepatocyte on a RGD-containing peptide coated polystyrene dish
    • Ijima H., and Kawakami K. Promote a monolayer formation and highly express the ammonia metabolism of primary rat hepatocyte on a RGD-containing peptide coated polystyrene dish. J. Biosci. Bioeng. 100 (2005) 62-66
    • (2005) J. Biosci. Bioeng. , vol.100 , pp. 62-66
    • Ijima, H.1    Kawakami, K.2
  • 15
    • 34147128196 scopus 로고    scopus 로고
    • Digoxin transport by renal proximal tubule cells is enhanced on adhesive synthetic RGD peptide
    • Ijima H., Kuroda S., and Kawakami K. Digoxin transport by renal proximal tubule cells is enhanced on adhesive synthetic RGD peptide. Int. J. Artif. Organs 30 (2007) 25-33
    • (2007) Int. J. Artif. Organs , vol.30 , pp. 25-33
    • Ijima, H.1    Kuroda, S.2    Kawakami, K.3
  • 16
    • 43849084251 scopus 로고    scopus 로고
    • Monolayer culture of primary rat hepatocytes on an Arg-Gly-Asp (RGD)-immobilized polystyrene dish express liver-specific functions of albumin production and p-acetamidophenol metabolism the same as for spheroid culture
    • Ijima H., and Kakeya Y. Monolayer culture of primary rat hepatocytes on an Arg-Gly-Asp (RGD)-immobilized polystyrene dish express liver-specific functions of albumin production and p-acetamidophenol metabolism the same as for spheroid culture. Biochem. Eng. J. 40 (2008) 387-391
    • (2008) Biochem. Eng. J. , vol.40 , pp. 387-391
    • Ijima, H.1    Kakeya, Y.2
  • 17
    • 0028076807 scopus 로고
    • Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth
    • Hansen L.K., Mooney D.J., Vacanti J.P., and Ingber D.E. Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth. Mol. Biol. Cell 5 (1994) 967-975
    • (1994) Mol. Biol. Cell , vol.5 , pp. 967-975
    • Hansen, L.K.1    Mooney, D.J.2    Vacanti, J.P.3    Ingber, D.E.4
  • 18
    • 69349101827 scopus 로고    scopus 로고
    • Hepatocyte growth factor and epidermal growth factor promote spheroid formation in polyurethane foam/hepatocyte culture and improve expression and maintenance of albumin production
    • 10.1016/j.bej.2009.06.012
    • Ijima H., Mizumoto H., Nakazawa K., Kajiwara T., Matsushita T., and Funatsu K. Hepatocyte growth factor and epidermal growth factor promote spheroid formation in polyurethane foam/hepatocyte culture and improve expression and maintenance of albumin production. Biochem. Eng. J. (2009) 10.1016/j.bej.2009.06.012
    • (2009) Biochem. Eng. J.
    • Ijima, H.1    Mizumoto, H.2    Nakazawa, K.3    Kajiwara, T.4    Matsushita, T.5    Funatsu, K.6
  • 19
    • 0031833040 scopus 로고    scopus 로고
    • Hepatocyte spheroids in polyurethane foams: functional analysis and application for a hybrid artificial liver
    • Ijima H., Matsushita T., Nakazawa K., Fujii Y., and Funatsu K. Hepatocyte spheroids in polyurethane foams: functional analysis and application for a hybrid artificial liver. Tissue Eng. 4 (1998) 213-226
    • (1998) Tissue Eng. , vol.4 , pp. 213-226
    • Ijima, H.1    Matsushita, T.2    Nakazawa, K.3    Fujii, Y.4    Funatsu, K.5
  • 20
    • 67651121678 scopus 로고    scopus 로고
    • Primary rat hepatocytes form spheroids on hepatocyte growth factor/heparin-immobilized collagen film and maintain high albumin production
    • Ijima H., Kubo T., and Hou Y.-T. Primary rat hepatocytes form spheroids on hepatocyte growth factor/heparin-immobilized collagen film and maintain high albumin production. Biochem. Eng. J. 46 (2009) 227-233
    • (2009) Biochem. Eng. J. , vol.46 , pp. 227-233
    • Ijima, H.1    Kubo, T.2    Hou, Y.-T.3
  • 21
    • 0028234605 scopus 로고
    • Hepatocyte growth factor immobilized onto culture substrates through heparin and matrigel enhances DNA synthesis in primary rat hepatocytes
    • Kato S., Ishii T., Hara H., Sugiura N., Kimata K., and Akamatsu N. Hepatocyte growth factor immobilized onto culture substrates through heparin and matrigel enhances DNA synthesis in primary rat hepatocytes. Exp. Cell Res. 211 (1994) 53-58
    • (1994) Exp. Cell Res. , vol.211 , pp. 53-58
    • Kato, S.1    Ishii, T.2    Hara, H.3    Sugiura, N.4    Kimata, K.5    Akamatsu, N.6
  • 22
    • 33746841799 scopus 로고    scopus 로고
    • Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro
    • Nahmias Y., Schwartz R.E., Hu W.S., Verfaillie C.M., and Odde D.J. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro. Tissue Eng. 12 (2006) 1627-1638
    • (2006) Tissue Eng. , vol.12 , pp. 1627-1638
    • Nahmias, Y.1    Schwartz, R.E.2    Hu, W.S.3    Verfaillie, C.M.4    Odde, D.J.5
  • 24
    • 0346158210 scopus 로고    scopus 로고
    • Development of a hybrid simulator for absorption and biotransformation processes in humans based on in vitro models of small intestine and liver tissues
    • Sakai Y., Fukuda O., Choi S.-H., and Sakoda A. Development of a hybrid simulator for absorption and biotransformation processes in humans based on in vitro models of small intestine and liver tissues. J. Artif. Organs 6 (2003) 273-281
    • (2003) J. Artif. Organs , vol.6 , pp. 273-281
    • Sakai, Y.1    Fukuda, O.2    Choi, S.-H.3    Sakoda, A.4
  • 25
    • 3042514111 scopus 로고    scopus 로고
    • Spheroid formation and expression of liver specific functions of primary rat hepatocytes co-cultured with bone marrow cells
    • Ijima H., Wang Y., and Langer R. Spheroid formation and expression of liver specific functions of primary rat hepatocytes co-cultured with bone marrow cells. Biochem. Eng. J. 20 (2004) 223-228
    • (2004) Biochem. Eng. J. , vol.20 , pp. 223-228
    • Ijima, H.1    Wang, Y.2    Langer, R.3
  • 26
    • 41549086477 scopus 로고    scopus 로고
    • The mixed co-culture effect of primary rat hepatocytes and bone marrow cells is caused by soluble factors derived from bone marrow cells
    • Ijima H., Matsuo T., and Kawakami K. The mixed co-culture effect of primary rat hepatocytes and bone marrow cells is caused by soluble factors derived from bone marrow cells. J. Biosci. Bioeng. 105 (2008) 226-231
    • (2008) J. Biosci. Bioeng. , vol.105 , pp. 226-231
    • Ijima, H.1    Matsuo, T.2    Kawakami, K.3
  • 27
    • 67349091108 scopus 로고    scopus 로고
    • Composition of culture medium is more important than co-culture with hepatic non-parenchymal cells in albumin production activity of primary rat hepatocytes, and the effect was enhanced by hepatocytes spheroid culture in collagen gel
    • Ijima H., Kakeya Y., Yokonuma T., Hou Y.-T., and Takei T. Composition of culture medium is more important than co-culture with hepatic non-parenchymal cells in albumin production activity of primary rat hepatocytes, and the effect was enhanced by hepatocytes spheroid culture in collagen gel. Biochem. Eng. J. 45 (2009) 226-231
    • (2009) Biochem. Eng. J. , vol.45 , pp. 226-231
    • Ijima, H.1    Kakeya, Y.2    Yokonuma, T.3    Hou, Y.-T.4    Takei, T.5
  • 28
    • 0030088133 scopus 로고    scopus 로고
    • Toward development of an implantable tissue engineered liver
    • Davis M.W., and Vacanti J.P. Toward development of an implantable tissue engineered liver. Biomaterials 17 (1996) 365-372
    • (1996) Biomaterials , vol.17 , pp. 365-372
    • Davis, M.W.1    Vacanti, J.P.2
  • 29
    • 0035690979 scopus 로고    scopus 로고
    • The efficacy of prevascularization by basic FGF for hepatocyte transplantation using polymer devices in rats
    • Ogawa K., Asonuma K., Inomata Y., Kim I., Ikada Y., Tabata Y., and Tanaka K. The efficacy of prevascularization by basic FGF for hepatocyte transplantation using polymer devices in rats. Cell Transplant. 10 (2001) 723-729
    • (2001) Cell Transplant. , vol.10 , pp. 723-729
    • Ogawa, K.1    Asonuma, K.2    Inomata, Y.3    Kim, I.4    Ikada, Y.5    Tabata, Y.6    Tanaka, K.7
  • 31
    • 0032471714 scopus 로고    scopus 로고
    • Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels
    • Kim S.S., Utsunomiya H., Koski J.A., Wu B.M., Cima M.J., Sohn J., Mukai K., Griffith L.G., and Vacanti J.P. Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels. Ann. Surg. 228 (1998) 8-13
    • (1998) Ann. Surg. , vol.228 , pp. 8-13
    • Kim, S.S.1    Utsunomiya, H.2    Koski, J.A.3    Wu, B.M.4    Cima, M.J.5    Sohn, J.6    Mukai, K.7    Griffith, L.G.8    Vacanti, J.P.9
  • 32
    • 33947138675 scopus 로고    scopus 로고
    • Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels
    • Takei T., Sakai S., Ijima H., and Kawakami K. Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels. J. Biosci. Bioeng. 103 (2007) 200-202
    • (2007) J. Biosci. Bioeng. , vol.103 , pp. 200-202
    • Takei, T.1    Sakai, S.2    Ijima, H.3    Kawakami, K.4
  • 33
    • 61449203717 scopus 로고    scopus 로고
    • Development of a practical small-scale circulation bioreactor and application to a drug metabolism simulator
    • Ijima H., Kakeya Y., Ogata T., and Sakai T. Development of a practical small-scale circulation bioreactor and application to a drug metabolism simulator. Biochem. Eng. J. 44 (2009) 292-296
    • (2009) Biochem. Eng. J. , vol.44 , pp. 292-296
    • Ijima, H.1    Kakeya, Y.2    Ogata, T.3    Sakai, T.4


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