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Volumn 24, Issue 3, 1997, Pages 235-242

Prolonged lidocaine metabolizing activity of primary hepatocytes with spheroid culture using polyurethane foam as a culture substratum

Author keywords

Drug metabolism simulator; Lidocaine MEGX; Monolayer culture; Polyurethane foam; Rat hepatocytes; Spheroid culture

Indexed keywords


EID: 0030967335     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007935016223     Document Type: Article
Times cited : (17)

References (11)
  • 1
    • 0026864194 scopus 로고
    • A stable long-term hepatocytes culture system for studies of physiologic processes: Cytokine stimulation of the acute phase response in rat and human hepatocytes
    • Bader A, Rinkes IHB, Closs IE, Ryan CM, Toner M, Cunningham JM, Tomkings GR and Yarmush ML (1992) A stable long-term hepatocytes culture system for studies of physiologic processes: cytokine stimulation of the acute phase response in rat and human hepatocytes. Biotechnology Progress 8: 219-225.
    • (1992) Biotechnology Progress , vol.8 , pp. 219-225
    • Bader, A.1    Rinkes, I.H.B.2    Closs, I.E.3    Ryan, C.M.4    Toner, M.5    Cunningham, J.M.6    Tomkings, G.R.7    Yarmush, M.L.8
  • 2
    • 0028124710 scopus 로고
    • Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals
    • Bader A, Zech K, Crome O, Cristians U, Ringe B, Pichlmayr R and Sewing K-FR (1994) Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals. Xenobiotica 24: 623-633.
    • (1994) Xenobiotica , vol.24 , pp. 623-633
    • Bader, A.1    Zech, K.2    Crome, O.3    Cristians, U.4    Ringe, B.5    Pichlmayr, R.6    Sewing, K.-F.R.7
  • 3
    • 0025320692 scopus 로고
    • Variation in drug-metaboling enzyme activities during the growth of human Hep G2 hepatoma
    • Doostdar H, Demoz A, Burke MD, Melvin WT and Grant MH (1990) Variation in drug-metaboling enzyme activities during the growth of human Hep G2 hepatoma. Xenobiotica 20: 435-441.
    • (1990) Xenobiotica , vol.20 , pp. 435-441
    • Doostdar, H.1    Demoz, A.2    Burke, M.D.3    Melvin, W.T.4    Grant, M.H.5
  • 4
    • 0024502767 scopus 로고
    • Hepatocyte function and extracellular matrix geometry: Long-term culture in a sandwich configuration
    • Dunn JC, Yarmush ML, Koebe HG and Tompkins RG (1989) Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB Journal 3: 174-177.
    • (1989) FASEB Journal , vol.3 , pp. 174-177
    • Dunn, J.C.1    Yarmush, M.L.2    Koebe, H.G.3    Tompkins, R.G.4
  • 5
    • 0024708337 scopus 로고
    • Alternatives to animals in toxicity testing
    • Goldberg AM and Frazier JM (1989) Alternatives to animals in toxicity testing. Scientific American 261: 16-2.
    • (1989) Scientific American , vol.261 , pp. 16-2
    • Goldberg, A.M.1    Frazier, J.M.2
  • 6
    • 0028351720 scopus 로고
    • Development of a hybrid artificial liver using multi capillary PUF/spheroid packed bed
    • Ijima H, Matsushita T and Funatsu K (1994) Development of a hybrid artificial liver using multi capillary PUF/spheroid packed bed. Japanese Journal of Artificial Organs 23: 463-468.
    • (1994) Japanese Journal of Artificial Organs , vol.23 , pp. 463-468
    • Ijima, H.1    Matsushita, T.2    Funatsu, K.3
  • 7
    • 0024366784 scopus 로고
    • Continued high albumin production by multicellular spheroids of adults rat hepatocytes formed in the presence of liver-derived proteoglycans
    • Koide N, Shinji T, Tanabe T, Asano K, Kawaguchi M, Sakaguchi K, Koide Y, Mori M and Tsuji T (1989) Continued high albumin production by multicellular spheroids of adults rat hepatocytes formed in the presence of liver-derived proteoglycans. Biochem. Biophys. Res. Comm. 161: 385-391.
    • (1989) Biochem. Biophys. Res. Comm. , vol.161 , pp. 385-391
    • Koide, N.1    Shinji, T.2    Tanabe, T.3    Asano, K.4    Kawaguchi, M.5    Sakaguchi, K.6    Koide, Y.7    Mori, M.8    Tsuji, T.9
  • 8
    • 0026069665 scopus 로고
    • High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam
    • Matsushita T, Ijima H, Koide N and Funatsu K (1991) High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam. Appl. Microbiol. Biotechnol. 36: 324-326.
    • (1991) Appl. Microbiol. Biotechnol. , vol.36 , pp. 324-326
    • Matsushita, T.1    Ijima, H.2    Koide, N.3    Funatsu, K.4
  • 10
    • 2742531211 scopus 로고
    • Substantivity and other factor responsible for formazan patterns in dehydrogenase histochemistry
    • Pearse AGE and Hess R (1961) Substantivity and other factor responsible for formazan patterns in dehydrogenase histochemistry. Experimentia 17: 136.
    • (1961) Experimentia , vol.17 , pp. 136
    • Pearse, A.G.E.1    Hess, R.2
  • 11
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Prescott DM (ed) Academic press, New York
    • Seglen PO (1976) Preparation of isolated rat liver cells. In: Prescott DM (ed) Methods Cell Biol, Vol 113, pp 29-83, Academic press, New York.
    • (1976) Methods Cell Biol , vol.113 , pp. 29-83
    • Seglen, P.O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.