Digoxin transport by renal proximal tubule cells is enhanced by adhesive synthetic RGD peptide

International Journal of Artificial Organs

Volumn 30, Issue 1, 2007, Pages 25-33

  Ijima, Hiroyuki ^a   Kuroda, S ^a   Ono, T ^a   Kawakami, K ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Active tranport; Digoxin; Renal proximal tubule cells; RGD; Transwell

Indexed keywords

AMINO ACIDS; ARTIFICIAL ORGANS; CELL ADHESION; CELL IMMOBILIZATION; COLLAGEN; GLYCOPROTEINS; MONOLAYERS;

ACTIVE TRANPORT; ARTIFICIAL KIDNEY; CELLS ADHESION; CONDITION; DIGOXIN; PRONECTIN F; PROXIMAL TUBULES; RENAL PROXIMAL TUBULE CELL; RGD; TRANSWELL;

CELLS;

ARGINYLGLYCYLASPARTIC ACID; COLLAGEN; DIGOXIN; FIBRONECTIN; GLYCOPROTEIN P; LAMININ; POLYCARBONATE; SYNTHETIC PEPTIDE;

ACTIVE TRANSPORT; ARTICLE; ARTIFICIAL KIDNEY; CELL ADHESION; CELL DENSITY; CELL KINETICS; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CONTROLLED STUDY; ELECTRIC RESISTANCE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMOBILIZED CELL; KIDNEY TUBULE CELL; MEMBRANE TRANSPORT; PROTEIN EXPRESSION;

EID: 34147128196     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880703000105     Document Type: Article

References (14)

1. Humes HD, Weitzel WF, Fissell WH. Renal cell therapy is associated with dynamic and individualized responses in patients with acute renal failure. Blood Purif 2003; 21: 64-71.
2. + active transport and morphological changes for bioartificial renal tubule cell device using mardin-darby canine kidney cells. Tissue Eng 2002; 8: 13-24.
3. Minguell JJ, Hardy CL, Tavassoli M. Adhesive interaction of hemopoietic progenitor cell membrane with the RGD domain of fibronectin. Biochim Bophys Acta 1993; 1151: 120-6.
4. Ijima H, Kawakami K. Promotion of monolayer formation and high expression of ammonia metabolism of primary rat hepatocytes on arginin-glycine-aspartic acid-containing peptide-coated polystyrene dish. J Biosci Bioeng 2005; 100: 62-6.
5. Tsuruoka S, Sugimoto KI, Ueda K, Suzuki M, Imai M, Fujimura A. Removal of digoxin and doxorubicin by multidrug resistance protein-overexpressed cell culture in hollow fiber. Kidney Int 1999; 56: 154-63.
6. Hori R, Okamura N, Aiba T and Tanigawa Y. Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney. J Pharmacol Exp Ther 1993; 266: 1620-5.
7. Endo M, Enosawa S, Ozaki M, Tsuruoka S, Hiramatsu S, Kim K, Omasa T, Matsumura T, Aoki T, Koyanagi Y and Suzuki S. Artificial mimicking of physiological active transport by a membrane co-cultured with two different cells: Hepatic origin HepG2 and renal origin PCTL-MDR. Artif Organs 2002; 26: 806-11.
8. Jin JS, Sakaeda T, Kakumoto M, Nishiguchi K, Nakamura T, Okamura N, Okumura K. Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs. Neurol Med Chir 2006; 46: 321-7.
9. Mooney D, Hansen L, Vacanti J, Langer R, Farmer S, Ingber D. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. J Cell Physiol 1992; 151: 497-505.
10. Tang VW, Goodenough DA. Paracellular ion channel at the tight junction. Biophys J 2003; 84: 1660-73.
11. Alexander JS, Elrod JW. Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation. J Anat 2002; 200: 561-74.
12. Pozzi A, Zent R. Integrins: sensors of extracellular matrix and modulators of cell function. Nephron Exp Nephrol 2003; 94: e77-e84.
13. Aumailley M, Gurrath M, Muller G, Calvete J, Timpl R, Kessler H. Arg-Gly-Asp constrained within cyclic pentapeptides: strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1. FEBS Lett 1991; 291: 50-4.
14. Ojakian GK, Ratcliffe DR, Schwimmer R. Integrin regulation of cell-cell adhesion during epithelial tubule formation. J Cell Sci 2000: 114: 941-52.