Camel's milk protects against cadmium chloride-induced hypocromic microcytic anemia and oxidative stress in red blood cells of white albino rats

American Journal of Pharmacology and Toxicology

Volumn 4, Issue 4, 2009, Pages 136-143

  Dallak, Mohammad ^a  

^a KING KHALID UNIVERSITY   (Saudi Arabia)

Author keywords

Cadmium chloride; Camel's milk; Hematological values; Oxidative system; Rats

Indexed keywords

ALUMINUM CHLORIDE; CADMIUM CHLORIDE; CAMEL MILK; CATALASE; FREE RADICAL; GLUTATHIONE; NATURAL PRODUCT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALUMINUM OVERLOAD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; IRON DEFICIENCY ANEMIA; MALE; MILK; NONHUMAN; OXIDATIVE STRESS; PROTECTION; RAT; RAT STRAIN;

RATTUS;

EID: 75349090915     PISSN: 15574962     EISSN: 15574970     Source Type: Journal    
DOI: 10.3844/ajptsp.2009.136.143     Document Type: Article

References (55)

1. Klos, A., 2001. Lead, cadmium and mercury content in metals planned for consumption in selected kindergartens in Warsaw. Proceeding of the 4th International Scientific-Technical Conference, (STC'01), Warsaw, pp: 4-5.
2. Vallee, B.L. and D.D. Ulmr, 1972. Biochemical effects of mercury, cadmium and lead. Ann. Rev. Biochem., 41: 91-128. http://www.ncbi.nlm.nih.gov/pubmed/ 4570963
3. McDowell, L.R., 1992. Minerals in Animal and Human Nutrition. Academic Press, New York, pp: 359-361.
4. Kowalczyk, E., K. Anna, F. Pawel, K. Maria, N. Jan, B. Jan, K. Jozef and T. Piotr, 2003. Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium. Acta Biochem. Polonica, 50: 543-548. http://www.ncbi.nlm.nih.gov/pubmed/12833179
5. Barrouillet, M.P., A. Moiret and J. Cambar, 1999. Protective effects of polyphenols against cadmium-induced glomerular mesangial cell myocontracture. Arch. Toxicol., 8-9: 485. http://www.ncbi.nlm.nih.gov/pubmed/10650921
6. Cai, Y.Q., H. Teranishi, K. Aoshima, T. Katoh, Y. Arai and N. Kasuya, 2001. Development of the fluorometric ELISA method for determination of alpha (1)-microglobulinuria in cadmium-polluted area in Japan. Int. Arch. Occupat. Environ. Health, 7: 514-518. http://direct.bl.uk/bld/PlaceOrder.do?UIN= 103087053&ETOC=RN&from=searchengine
7. Liu, J., Y.P. Liu, S.M. Habeebu, M.P. Waalkes and C.D. Klaassen, 2000. Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein I/II null mice. Toxicology, 147: 157-166. http://www.ncbi.nlm.nih.gov/pubmed/10924798
8. Shaikh, Z.A., T.T. Vu and K. Zaman, 1999. Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. Toxicol. Applied Pharmacol., 154: 256. http://cat.inist.fr/? aModele=afficheN&cpsidt=1729886
9. Stohs, S.I., D., Bagchi, E. Hassoun and M. Bagchi, 2000. Oxidative mechanisms in the toxicity of chromium and cadmium ions. J. Environ. Pathol. Toxicol. Oncol., 19: 201-213. http://www.ncbi.nlm.nih.gov/pubmed/10983887
10. Murata, I., T. Hirona, Y. Saeki and S. Nakagawa, 1970. Cadmium enteropathy renal osteomalacia (Itai-Itai" disease in Japan) Bull. Soc. Int. Chir., 29: 34-42. http://www.ncbi.nlm.nih.gov/pubmed/5510186
11. Kazantzis, G., F.V. Flynn and J.S. Spowage, 1963. Trott DG Renal tubular malfunction and pulmonary emphysema in cadmium pigment workers. Q. J. Med., 32: 165-192. http://www.ncbi.nlm.nih.gov/pubmed/14031597
12. Groten, J.P., E.J. Sinkeldam, J.B. Luten and P.J. Bladeren, 1990. Comparison of the toxicity of inorganic and liver-incorporated cadmium: A four-week feeding study in rats. Food Chem. Toxicol., 28: 435-441. http://www.ncbi.nlm.nih.gov/pubmed/2210516
13. Elinder, C.G., 1985. Cadmium uses, Occurrence and Intake. In: Cadmium and Health: A Toxicological and epidemiological Apprisal, Exposure, Dose and Metabolism, Feriberg, L.E., C.G. Elinder, T. Kjellstrom and G.F. Nordberg (Eds.). CRC Press, Boca Raton FL., ISBN: 0849366909, pp: 23-63.
14. Ericson, A., B. Gallen and P. Weterholm, 1979. Cigarette smoking as an etiological factor in cleft lip and palate. Am. J. Obstet. Gynecol., 135: 348-351. http://www.ncbi.nlm.nih.gov/pubmed/484624
15. Simpkins, C., T. Lloyd, S. Li and S. Balderman, 1998. Metallothionein-induced increase in mitochondrial inner membrane permeability. J. Surg. Res., 75: 30-34. http://www.ncbi.nlm.nih.gov/pubmed/9614853
16. Sarkar, S., P. Yadav, R. Trivedi, A.K. Bansal and D. Bhatnager, 1995. Cadmium-induced lipid peroxidation and the status antioxidant system in rat tissues. J. Trace Elem. Med. Biol., 9: 144-149. http://www.ncbi.nlm.nih.gov/ pubmed/8605602
17. Kostić, M.M., B. Ognjanović, S. Dimitrijević, R.V. Ikić,Tajn, G.l. Rosić and R.V. Ivković, 1993. Cadmium induced changes of antioxidant and metabolic status in red blood cells of rats: In vivo effects. Eur. J. Haematol., 51: 86-92. http://www.ncbi.nlm.nih. gov/pubmed/8370423
18. Schafer, S.G. and W. Forth, 1984. The interaction between Cadmium and iron. A review of the literature, Trace Elem. Med. Paul. J. Cell., 2: 158-162.
19. Shukla, G.S. and S.V. Chandra, 1989. Cadmium toxicity and bioantioxidants: Status of vitamin E and ascorbic acid of selected organs in rat. J. Applied Toxicol., 9: 119-122. http://www.ncbi.nlm.nih.gov/pubmed/2715567
20. Ognjanović, B.I., S.Z. Pavlović, R.V. A. Ikić Tajn, S.D. Maletić. Z.S. Saičić and V.M. Petrović, 2000. The e activities and blood hematological values of rats exposed to cadmium. Kragujevac J. Sci., 22: 93-99.
21. Fariss, M.W., 1991. Cadmium toxicity: Unique cytoprotective properties of alpha tocopheryl succinate in hepatocytes. Toxicology, 69: 63-77. http://www.ncbi.nlm.nih.gov/pubmed/1926156
22. Knoess K.H., 1979. Milk production of the dromedary. Proceeding of the IFS Symposium Camels, (SC'79), Sudan, pp: 201-214.
23. Rao, M.B., R.C. Gupta and N.N. Dastur, 1970. Camels' milk and milk products. Indian J. Dairy Sci., 23: 71-78.
24. Mal, G., D.S. Sena, V.K. Jain and M.S. Sahani, 2001. Therapeutic utility of camel milk as nutritional supplement in chronic pulmonary tuberculosis. Livestock Int., pp: 4-8.
25. Agrawal, R.P., S.C. Swami, R. Beniwal, D.K. Kochar and R.P. Kothari, 2002. Effect of camel milk on glycemic control, risk factors and diabetes quality of life in type-1 diabetes: A randomized prospective controlled study. Int. J. Diabetes Develop. Counties, 22: 70-74. http://www.ijddc.com/article.asp? issn=0973-3930;year=2002;volume=22;issue=2;spage=70;epage=74;aulast=Agrawal
26. Chanarin, I., 1989. Laboratory haematology. An Account of Laboratory Techniques. Churchill Livingstone, Hong Kong.
27. Drabkin, D.L. and J.H., Austin, 1993. Spectrophotometer studies for common hemoglobin derivatives in human; dog and rabbit. J. Biol. Chem., 98: 719-725. http://www.jbc.org/cgi/content/citation/98/2/719
28. Sedlak., J. and R.H. Lindsay, 1968. Estimation of total protein bound and non-protein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem., 25: 293-98. http://www.ncbi.nlm.nih.gov/pubmed/4973948
29. Swiergosz, R., M. Zakrzewska, K.S. Kapusta, K. Bacia and I. Jankowska, 1998. Accumulation of cadmium and its effect on bank vole tissues after chronic exposure. Ecotoxicol. Environ. Safe., 41: 130-136. http://cat.inist.fr/?aModele= afficheN&cpsidt=1627432
30. Dhanapakiam, P. and V.K. Ramasamy, 2001. Toxic effects of copper and zink mixture on some haematological and biochemical parameters in common crap, Cyprnus carpio (Linn). J. Environ. Biol., 22: 105-111. http://www.ncbi.nlm.nih.gov/pubmed/11500014
31. Bersenyi, A., S.G. Feket, Z. Szocs and E. Berta, 2003. Effect of ingested heavy metals (Cd, Pb, Hg) on hematology and serum biochemistry in rabbits. Acta Vet. Hung., 51: 297-304. http://www.ncbi.nlm.nih.gov/pubmed/14516158
32. 3 to its SCE-inducing form. Mutat. Res., 141: 49-53. http://www.ncbi.nlm.nih.gov/pubmed/6482895
33. Rahman, I., S.K. J. Biswas, L.A. Menez, M. Torres and H. Jay Forman, 2005. Glutathione, stress responses and redox signaling in lung inflammation. Antioxid. Redox Signal., 7: 45-59. http://www.ncbi.nlm.nih.gov/pubmed/15650395
34. Elman, G.K., 1959. Tissue sulfhdryl groups. Arch. Biochem. Biophys., 8: 70-77. http://www.ncbi.nlm.nih.gov/pubmed/13650640
35. Hooiveld, M., D.J.J. Heederick, M. Kogevinas, P. Boffetta and L.L. Needham et al., 1998. Second follow-up of a duch cohort occupationally exposed to phenoxy herbicydes, chlorophenols and contaminants. Am. J. Epidemiol., 147: 891-901.
36. Hiratsuka, H., O. Katsuta, N. Toyota, M. Tsuchitani, T. Umemura and F. Marumo, 1996. Chronic cadmium exposure-induced renal anemia in ovariectomized rats. Toxicol. Applied Pharmacol., 137: 228-236. DOI: 10.1006/taap.1996.0076
37. Mackova, N.O., S. Lenikova, P. Fedorocko and P. Brezani, 1996. Effects of cadmium on haemopoiesis in irradiated and nonirradiated mice: Relationship to the number of circulating blood cells and haemopoiesis. Physiol. Res., 45: 101-106. http://www.ncbi.nlm.nih.gov/pubmed/9496758
38. Chun, Y.S., E. Choi, G.T. Kim, H. Choi, C.H. Kim, M.J. Lee, S. Kim and J.W. Park, 2000. Cadmium blocks Hypoxia-Inducible Factor (HIF)-1-mediated response to hypoxia by stimulating the proteasomedependent degradation of HIF-1alpha. Eur. J. Biochem., 267: 4198-204. http://www.ncbi.nlm.nih.gov/pubmed/ 10866824
39. Yamano, T., S.D. Kosanke and L.E. Rikans, 1999. Attenuation of cadmium-induced liver injury in senescent male Fischer 344 rats: Role of metallothionein and glutathione. Toxicol. Applied Pharmacol., 161: 225-230. http://www.ncbi.nlm.nih.gov/pubmed/10620479
40. Yiin, S.J., C.L. Chern, J.Y. Sheu, W.C. Tseng and T.H. Lin, 1999. Cadmium induced renal lipid peroxidation in rats and protection by selenium. J. Toxicol. Environ. Health, 57: 403-413. http://www.ncbi.nlm.nih.gov/pubmed/ 10478822
41. Moore, M.R., A. Goldberg and A.C. Yeung-Laiwah, 1987. Lead effects on the hemebiosynthetic pathway. Ann. N. Y. Acad. Sci., 514: 191-202. DOI: 10.1111/j.1749-6632.1987.tb48774.x
42. Li, W., Y. Zhao and I.N. Chou, 1993. Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions. Toxicology, 77: 65-79. http://www.ncbi.nlm.nih.gov/pubmed/8442019
43. Chiu, D., F. Kuypers and B. Lubin, 1989. Lipid peroxidation in human red cells. Semin. Hematol., 26: 257-276. http://www.ncbi.nlm.nih.gov/pubmed/2683096
44. Babu, K.R., H.R. Rajmohan, B.K. Rajan and K.M. Kumar, 2006. Plasma lipid peroxidation and erythrocyte antioxidant enzymes status in workers exposed to cadmium. Toxicol. Ind. Health, 22: 329-335. http://www.ncbi.nlm.nih.gov/pubmed/ 17120531
45. Martin, H.L., Richert and A. Berthelot, 2003. Magnesium deficiency induces apoptosis in primary cultures of rat hepatocytes. J. Nutr., 133: 2505-2511. http://www.ncbi.nlm.nih.gov/pubmed/12888628
46. Barbagallo, M., 1999. Effects of vitamin E and glutathione on glucose metabolism: Role of magnesium. Hypertension, 34: 1002-1006. http://www.ncbi.nlm. nih.gov/pubmed/10523398
47. Virginia, M., M.B. Smith, M.J. Brauner and W. Phili, 1971. Majerus. Glutathione biosynthesis in human erythrocytes. I. Identification of the enzymes of glutathione synthesis in hemolysates. J. Clin. Invest., 50: 507-513. http://www.ncbi.nlm.nih.gov/pubmed/5545117
48. Frederickson, C.J., 1989. Neurobiology of zinc and zinc containing neurons. Int. Rev. Neurobiol., 31: 145-238. http://www.ncbi.nlm.nih.gov/pubmed/ 2689380
49. Powell, S.R., 2000. Antioxidant properties of zinc. J. Nutr., 130: 1447-1454. http://jn.nutrition.org/cgi/content/abstract/130/5/1447S
50. Ozturk, A., A.K Baltaci, R. Mogulkoc, E. Oztekin, A. Sivrikaya, E. Kurtogh and A. Kul, 2003. Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissue of rats performing swimming exercise. Biol. Trace Elem. Res., 94: 157-166. http://www.ncbi.nlm.nih. gov/pubmed/14716102
51. Ozdemir, G. and F. Inanc, 2005. Zinc may protect remote ocular injury caused by intestinal ischemia reperfusion in rats. Tohoku J. Exp. Med., 206: 247-251. http://www.ncbi.nlm.nih.gov/pubmed/15942153
52. Sato, M. and I. Bremner, 1993. Oxygen free radicals and metalothionein. Free Radic. Biol. Med., 14: 325-327. http://www.ncbi.nlm.nih.gov/pubmed/8458590
53. Shaheen, A.A. and A.A. El-Fattah, 1995. Effect of dietary zinc on lipid peroxidation, glutathione, protein levels and superoxide dismutase activity in rat tissues. Int. J. Biochem. Cell. Biol., 27: 89-95. http://www.ncbi.nlm.nih. gov/pubmed/7757885
54. Bray, T.M. and W.J. Bettger, 1990. The physiological role of zinc as an antioxidant. Free Radic. Biol. Med., 8: 281-291. http://www.ncbi.nlm.nih.gov/ pubmed/2187766
55. Goering, P.L. and C.D. Klaassen, 1984. Zinc-induced tolerance to cadmium hepatotoxicity. Toxicol. Applied Pharmacol., 74: 299-307. http://www.ncbi.nlm. nih.gov/pubmed/6740679