Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice

Toxicology

Volumn 147, Issue 3, 2000, Pages 157-166

  Liu, Jie ^a   Liu, Yaping ^b   Habeebu, Sultan M ^b   Waalkes, Michael P ^a   Klaassen, Curtis D ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Arsenite; Cadmium; Chronic oral exposure; Metallothionein; Metallothionein I II null mice; Nephrotoxicity

Indexed keywords

ARSENATE SODIUM; ARSENIC; CADMIUM; CADMIUM CHLORIDE; METALLOTHIONEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; HEAVY METAL POISONING; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY INJURY; LONG TERM EXPOSURE; MOUSE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TISSUE LEVEL;

ACETYLGLUCOSAMINIDASE; ADMINISTRATION, ORAL; ANIMALS; ARSENIC; BODY WEIGHT; CADMIUM; DRUG ADMINISTRATION SCHEDULE; DRUG SYNERGISM; GLYCOSURIA; KIDNEY; KIDNEY DISEASES; LIVER; MALE; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; ORGAN SIZE; PROTEINURIA;

ANIMALIA;

EID: 0034608774     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00194-3     Document Type: Article

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