Pichia pastoris as a host for secretion of toxic saporin chimeras

FASEB Journal

Volumn 24, Issue 1, 2010, Pages 253-265

  Lombardi, Alessio ^a   Bursomanno, Sara ^a   Lopardo, Teresa ^a   Traini, Roberta ^a   Colombatti, Marco ^b   Ippoliti, Rodolfo ^c   Flavell, David J ^d,e   Flavell, Sopsamorn U ^d,e   Ceriotti, Aldo ^a   Fabbrini, Maria Serena ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d Leukaemia Busters (Clinical Trials Support Unit)   (United Kingdom)

^e SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Codon usage; Eukaryotic expression; Human urokinase receptor; Plant ribosome inactivating proteins; Tumor targeted therapy

Indexed keywords

SAPORIN; UROKINASE;

ARTICLE; CATALYSIS; CHIMERA; CODON USAGE; IC 50; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING;

BASE SEQUENCE; BINDING SITES; CODON; DNA PRIMERS; GENE EXPRESSION; HUMANS; IMMUNOTOXINS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; N-GLYCOSYL HYDROLASES; PICHIA; PLANT PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; RIBOSOME INACTIVATING PROTEINS, TYPE 1; TRANSFORMATION, GENETIC; U937 CELLS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

BACTERIA (MICROORGANISMS); EUKARYOTA; PICHIA PASTORIS;

EID: 75149187924     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-118042     Document Type: Article

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