Host-mediated antibody-dependent cellular cytotoxicity contributes to the in vivo therapeutic efficacy of an anti-CD7-saporin immunotoxin in a severe combined immunodeficient mouse model of human T-cell acute lymphoblastic leukemia

Cancer Research

Volumn 58, Issue 24, 1998, Pages 5787-5794

  Flavell, David J ^a,b   Warnes, Sarah ^a   Noss, Armorel ^a   Flavell, Sopsamorn U ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD7 ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOTOXIN; SAPORIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL MODEL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MIXTURE; DRUG POTENCY; FEMALE; HOST; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IMMUNOTHERAPY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SCID MOUSE; T LYMPHOCYTE;

ANIMALS; ANTIBODIES; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; ANTIGENS, CD7; CELL DIVISION; IMMUNOCONJUGATES; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOPHENOTYPING; IMMUNOTOXINS; LEUKEMIA, T-CELL, ACUTE; MICE; MICE, SCID; N-GLYCOSYL HYDROLASES; PLANT PROTEINS; PROTEIN SYNTHESIS INHIBITORS; SPLEEN;

EID: 0032535057     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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