-
1
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe, D. J. (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81, 741-766
-
(2001)
Physiol. Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
2
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., and Pericak-Vance, M. A. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
3
-
-
0034305790
-
Apolipoprotein E receptors: Linking brain development and Alzheimer's disease
-
Herz, J., and Beffert, U. (2000) Apolipoprotein E receptors: linking brain development and Alzheimer's disease. Nat. Rev. Neurosci. 1, 51-58
-
(2000)
Nat. Rev. Neurosci
, vol.1
, pp. 51-58
-
-
Herz, J.1
Beffert, U.2
-
4
-
-
33750333569
-
Reelin, lipoprotein receptors and synaptic plasticity
-
Herz, J., and Chen, Y. (2006) Reelin, lipoprotein receptors and synaptic plasticity. Nat. Rev. Neurosci. 7, 850-859
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 850-859
-
-
Herz, J.1
Chen, Y.2
-
5
-
-
0029746156
-
Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein
-
Guenette, S. Y., Chen, J., Jondro, P. D., and Tanzi, R. E. (1996) Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein. Proc. Natl. Acad. Sci. U. S. A. 93, 10832-10837
-
(1996)
Proc. Natl. Acad. Sci. U. S. A
, vol.93
, pp. 10832-10837
-
-
Guenette, S.Y.1
Chen, J.2
Jondro, P.D.3
Tanzi, R.E.4
-
6
-
-
0034682827
-
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
-
Gotthardt, M., Trommsdorff, M., Nevitt, M. F., Shelton, J., Richardson, J. A., Stockinger, W., Nimpf, J., and Herz, J. (2000) Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. J. Biol. Chem. 275, 25616-25624
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25616-25624
-
-
Gotthardt, M.1
Trommsdorff, M.2
Nevitt, M.F.3
Shelton, J.4
Richardson, J.A.5
Stockinger, W.6
Nimpf, J.7
Herz, J.8
-
7
-
-
33845925306
-
Dab1 and Reelin effects on APP and ApoEr2 trafficking and processing
-
Hoe, H. S., Tran, T. S., Matsuoka, Y., Howell, B. W., and Rebeck, G. W. (2006) Dab1 and Reelin effects on APP and ApoEr2 trafficking and processing. J. Biol. Chem. 281, 35176-35185
-
(2006)
J. Biol. Chem
, vol.281
, pp. 35176-35185
-
-
Hoe, H.S.1
Tran, T.S.2
Matsuoka, Y.3
Howell, B.W.4
Rebeck, G.W.5
-
8
-
-
33747692276
-
FE65 interaction with the apoE receptor ApoEr2
-
Hoe, H. S., Magill, L. A., Fu, Z., Vicini, S., and Rebeck, G. W. (2006) FE65 interaction with the apoE receptor ApoEr2. J. Biol. Chem. 281, 24521-24530
-
(2006)
J. Biol. Chem
, vol.281
, pp. 24521-24530
-
-
Hoe, H.S.1
Magill, L.A.2
Fu, Z.3
Vicini, S.4
Rebeck, G.W.5
-
9
-
-
37549040612
-
A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference
-
Young-Pearse, T. L., Bai, J., Chang, R., Zheng, J. B., LoTurco, J. J., and Selkoe, D. J. (2007) A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J. Neurosci. 27, 14459-14469
-
(2007)
J. Neurosci
, vol.27
, pp. 14459-14469
-
-
Young-Pearse, T.L.1
Bai, J.2
Chang, R.3
Zheng, J.B.4
LoTurco, J.J.5
Selkoe, D.J.6
-
10
-
-
37349015897
-
A genetic interaction between the APP and Dab1 genes influences brain development
-
Pramatarova, A., Chen, K., and Howell, B. W. (2008) A genetic interaction between the APP and Dab1 genes influences brain development. Mol. Cell. Neurosci. 37, 178-186
-
(2008)
Mol. Cell. Neurosci
, vol.37
, pp. 178-186
-
-
Pramatarova, A.1
Chen, K.2
Howell, B.W.3
-
11
-
-
0033624279
-
Reelin binds α3β1 integrin and inhibits neuronal migration
-
Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., and Anton, E. S. (2000) Reelin binds α3β1 integrin and inhibits neuronal migration. Neuron 27, 33-44
-
(2000)
Neuron
, vol.27
, pp. 33-44
-
-
Dulabon, L.1
Olson, E.C.2
Taglienti, M.G.3
Eisenhuth, S.4
McGrath, B.5
Walsh, C.A.6
Kreidberg, J.A.7
Anton, E.S.8
-
12
-
-
0034633703
-
The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-d-aspartate receptors
-
Bacskai, B. J., Xia, M. Q., Strickland, D. K., Rebeck, G. W., and Hyman, B. T. (2000) The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-d-aspartate receptors. Proc. Natl. Acad. Sci. U. S. A. 97, 11551-11556
-
(2000)
Proc. Natl. Acad. Sci. U. S. A
, vol.97
, pp. 11551-11556
-
-
Bacskai, B.J.1
Xia, M.Q.2
Strickland, D.K.3
Rebeck, G.W.4
Hyman, B.T.5
-
13
-
-
23744516021
-
Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2
-
Beffert, U., Weeber, E. J., Durudas, A., Qiu, S., Masiulis, I., Sweatt, J. D., Li, W. P., Adelmann, G., Frotscher, M., Hammer, R. E., and Herz, J. (2005) Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 47, 567-579
-
(2005)
Neuron
, vol.47
, pp. 567-579
-
-
Beffert, U.1
Weeber, E.J.2
Durudas, A.3
Qiu, S.4
Masiulis, I.5
Sweatt, J.D.6
Li, W.P.7
Adelmann, G.8
Frotscher, M.9
Hammer, R.E.10
Herz, J.11
-
14
-
-
58149389019
-
Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3
-
Chai, X., Forster, E., Zhao, S., Bock, H. H., and Frotscher, M. (2009) Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. J. Neurosci. 29, 288-299
-
(2009)
J. Neurosci
, vol.29
, pp. 288-299
-
-
Chai, X.1
Forster, E.2
Zhao, S.3
Bock, H.H.4
Frotscher, M.5
-
15
-
-
0035954426
-
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
-
Sabo, S. L., Ikin, A. F., Buxbaum, J. D., and Greengard, P. (2001) The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J. Cell Biol. 153, 1403-1414
-
(2001)
J. Cell Biol
, vol.153
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
16
-
-
0035816661
-
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60
-
Cao, X., and Sudhof, T. C. (2001) A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293, 115-120
-
(2001)
Science
, vol.293
, pp. 115-120
-
-
Cao, X.1
Sudhof, T.C.2
-
17
-
-
2542423595
-
The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling
-
Perkinton, M. S., Standen, C. L., Lau, K. F., Kesavapany, S., Byers, H. L., Ward, M., McLoughlin, D. M., and Miller, C. C. (2004) The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling. J. Biol. Chem. 279, 22084-22091
-
(2004)
J. Biol. Chem
, vol.279
, pp. 22084-22091
-
-
Perkinton, M.S.1
Standen, C.L.2
Lau, K.F.3
Kesavapany, S.4
Byers, H.L.5
Ward, M.6
McLoughlin, D.M.7
Miller, C.C.8
-
18
-
-
0031465172
-
Mint, Munc 18-interacting proteins in synaptic vesicle exocytosis
-
Okamoto, M., and Sudhof, T. C. (1997) Mint, Munc 18-interacting proteins in synaptic vesicle exocytosis. J. Biol. Chem. 272, 31459-31464
-
(1997)
J. Biol. Chem
, vol.272
, pp. 31459-31464
-
-
Okamoto, M.1
Sudhof, T.C.2
-
19
-
-
0033610842
-
Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting
-
Borg, J. P., Straight, S. W., Kaech, S. M., de Taddeo-Borg, M., Kroon, D. E., Karnak, D., Turner, R. S., Kim, S. K., and Margolis, B. (1998) Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting. J. Biol. Chem. 273, 31633-31636
-
(1998)
J. Biol. Chem
, vol.273
, pp. 31633-31636
-
-
Borg, J.P.1
Straight, S.W.2
Kaech, S.M.3
de Taddeo-Borg, M.4
Kroon, D.E.5
Karnak, D.6
Turner, R.S.7
Kim, S.K.8
Margolis, B.9
-
20
-
-
0032575559
-
X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion
-
Sastre, M., Turner, R. S., and Levy, E. (1998) X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion. J. Biol. Chem. 273, 22351-22357
-
(1998)
J. Biol. Chem
, vol.273
, pp. 22351-22357
-
-
Sastre, M.1
Turner, R.S.2
Levy, E.3
-
21
-
-
0033593480
-
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein
-
Tomita, S., Ozaki, T., Taru, H., Oguchi, S., Takeda, S., Yagi, Y., Sakiyama, S., Kirino, Y., and Suzuki, T. (1999) Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. J. Biol. Chem. 274, 2243-2254
-
(1999)
J. Biol. Chem
, vol.274
, pp. 2243-2254
-
-
Tomita, S.1
Ozaki, T.2
Taru, H.3
Oguchi, S.4
Takeda, S.5
Yagi, Y.6
Sakiyama, S.7
Kirino, Y.8
Suzuki, T.9
-
22
-
-
34247112490
-
Apolipoprotein receptor 2 and X11 α/β mediate apolipoprotein E-induced endocytosis of amyloid-β precursor protein and beta-secretase, leading to amyloid-beta production
-
He, X., Cooley, K., Chung, C. H., Dashti, N., and Tang, J. (2007) Apolipoprotein receptor 2 and X11 α/β mediate apolipoprotein E-induced endocytosis of amyloid-β precursor protein and beta-secretase, leading to amyloid-beta production. J. Neurosci. 27, 4052-4060
-
(2007)
J. Neurosci
, vol.27
, pp. 4052-4060
-
-
He, X.1
Cooley, K.2
Chung, C.H.3
Dashti, N.4
Tang, J.5
-
23
-
-
20444409468
-
Regulation of ApoE receptor proteolysis by ligand binding
-
Hoe, H. S., and Rebeck, G. W. (2005) Regulation of ApoE receptor proteolysis by ligand binding. Brain Res. Mol. Brain Res. 137, 31-39
-
(2005)
Brain Res. Mol. Brain Res
, vol.137
, pp. 31-39
-
-
Hoe, H.S.1
Rebeck, G.W.2
-
24
-
-
0025129726
-
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
-
Soule, H. D., Maloney, T. M., Wolman, S. R., Peterson, W. D., Jr., Brenz, R., McGrath, C. M., Russo, J., Pauley, R. J., Jones, R. F., and Brooks, S. C. (1990) Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50, 6075-6086
-
(1990)
Cancer Res
, vol.50
, pp. 6075-6086
-
-
Soule, H.D.1
Maloney, T.M.2
Wolman, S.R.3
Peterson Jr., W.D.4
Brenz, R.5
McGrath, C.M.6
Russo, J.7
Pauley, R.J.8
Jones, R.F.9
Brooks, S.C.10
-
25
-
-
0035797521
-
Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP
-
Pak, D. T., Yang, S., Rudolph-Correia, S., Kim, E., and Sheng, M. (2001) Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron 31, 289-303
-
(2001)
Neuron
, vol.31
, pp. 289-303
-
-
Pak, D.T.1
Yang, S.2
Rudolph-Correia, S.3
Kim, E.4
Sheng, M.5
-
26
-
-
0029805132
-
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein
-
Borg, J. P., Ooi, J., Levy, E., and Margolis, B. (1996) The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol. Cell. Biol. 16, 6229-6241
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 6229-6241
-
-
Borg, J.P.1
Ooi, J.2
Levy, E.3
Margolis, B.4
-
27
-
-
44449121473
-
Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing
-
Hoe, H. S., Minami, S. S., Makarova, A., Lee, J., Hyman, B. T., Matsuoka, Y., and Rebeck, G. W. (2008) Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. J. Biol. Chem. 283, 6288-6299
-
(2008)
J. Biol. Chem
, vol.283
, pp. 6288-6299
-
-
Hoe, H.S.1
Minami, S.S.2
Makarova, A.3
Lee, J.4
Hyman, B.T.5
Matsuoka, Y.6
Rebeck, G.W.7
-
28
-
-
67049155952
-
Apolipoprotein E receptors in the nervous system
-
Herz, J. (2009) Apolipoprotein E receptors in the nervous system. Curr. Opin. Lipidol. 20, 190-196
-
(2009)
Curr. Opin. Lipidol
, vol.20
, pp. 190-196
-
-
Herz, J.1
-
29
-
-
0033003134
-
Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
-
Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., and Herz, J. (1999) Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell 97, 689-701
-
(1999)
Cell
, vol.97
, pp. 689-701
-
-
Trommsdorff, M.1
Gotthardt, M.2
Hiesberger, T.3
Shelton, J.4
Stockinger, W.5
Nimpf, J.6
Hammer, R.E.7
Richardson, J.A.8
Herz, J.9
-
30
-
-
33645211958
-
Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts
-
Mayer, H., Duit, S., Hauser, C., Schneider, W. J., and Nimpf, J. (2006) Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts. Mol. Cell. Biol. 26, 19-27
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 19-27
-
-
Mayer, H.1
Duit, S.2
Hauser, C.3
Schneider, W.J.4
Nimpf, J.5
-
31
-
-
0034626631
-
Fe65 and X11beta co-localize with and compete for binding to the amyloid precursor protein
-
Lau, K. F., McLoughlin, D. M., Standen, C. L., Irving, N. G., and Miller, C. C. (2000) Fe65 and X11beta co-localize with and compete for binding to the amyloid precursor protein. Neuroreport 11, 3607-3610
-
(2000)
Neuroreport
, vol.11
, pp. 3607-3610
-
-
Lau, K.F.1
McLoughlin, D.M.2
Standen, C.L.3
Irving, N.G.4
Miller, C.C.5
-
32
-
-
33846651249
-
Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha
-
Parisiadou, L., and Efthimiopoulos, S. (2007) Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha. Neurobiol. Aging 28, 377-388
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 377-388
-
-
Parisiadou, L.1
Efthimiopoulos, S.2
-
33
-
-
0344012486
-
The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice
-
Lee, J. H., Lau, K. F., Perkinton, M. S., Standen, C. L., Shemilt, S. J., Mercken, L., Cooper, J. D., McLoughlin, D. M., and Miller, C. C. (2003) The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. J. Biol. Chem. 278, 47025-47029
-
(2003)
J. Biol. Chem
, vol.278
, pp. 47025-47029
-
-
Lee, J.H.1
Lau, K.F.2
Perkinton, M.S.3
Standen, C.L.4
Shemilt, S.J.5
Mercken, L.6
Cooper, J.D.7
McLoughlin, D.M.8
Miller, C.C.9
-
34
-
-
10344227214
-
The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice
-
Lee, J. H., Lau, K. F., Perkinton, M. S., Standen, C. L., Rogelj, B., Falinska, A., McLoughlin, D. M., and Miller, C. C. (2004) The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice. J. Biol. Chem. 279, 49099-49104
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49099-49104
-
-
Lee, J.H.1
Lau, K.F.2
Perkinton, M.S.3
Standen, C.L.4
Rogelj, B.5
Falinska, A.6
McLoughlin, D.M.7
Miller, C.C.8
-
35
-
-
0034671933
-
Modulation of amyloid precursor protein metabolism by X11alpha/Mint-1. A deletion analysis of protein-protein interaction domains
-
Mueller, H. T., Borg, J. P., Margolis, B., and Turner, R. S. (2000) Modulation of amyloid precursor protein metabolism by X11alpha/Mint-1. A deletion analysis of protein-protein interaction domains. J. Biol. Chem. 275, 39302-39306
-
(2000)
J. Biol. Chem
, vol.275
, pp. 39302-39306
-
-
Mueller, H.T.1
Borg, J.P.2
Margolis, B.3
Turner, R.S.4
-
36
-
-
0025250145
-
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor
-
Chen, W. J., Goldstein, J. L., and Brown, M. S. (1990) NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J. Biol. Chem. 265, 3116-3123
-
(1990)
J. Biol. Chem
, vol.265
, pp. 3116-3123
-
-
Chen, W.J.1
Goldstein, J.L.2
Brown, M.S.3
-
37
-
-
30044451745
-
The adaptor protein X11Lα/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila
-
Vishnu, S., Hertenstein, A., Betschinger, J., Knoblich, J. A., Gert de Couet, H., and Fischbach, K. F. (2006) The adaptor protein X11Lα/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Dev. Biol. 289, 296 -307
-
(2006)
Dev. Biol
, vol.289
, pp. 296-307
-
-
Vishnu, S.1
Hertenstein, A.2
Betschinger, J.3
Knoblich, J.A.4
Gert de Couet, H.5
Fischbach, K.F.6
-
38
-
-
0035139220
-
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis
-
Penzes, P., Johnson, R. C., Sattler, R., Zhang, X., Huganir, R. L., Kambampati, V., Mains, R. E., and Eipper, B. A. (2001) The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Neuron 29, 229-242
-
(2001)
Neuron
, vol.29
, pp. 229-242
-
-
Penzes, P.1
Johnson, R.C.2
Sattler, R.3
Zhang, X.4
Huganir, R.L.5
Kambampati, V.6
Mains, R.E.7
Eipper, B.A.8
-
39
-
-
36549059188
-
Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons
-
Hack, I., Hellwig, S., Junghans, D., Brunne, B., Bock, H. H., Zhao, S., and Frotscher, M. (2007) Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development 134, 3883-3891
-
(2007)
Development
, vol.134
, pp. 3883-3891
-
-
Hack, I.1
Hellwig, S.2
Junghans, D.3
Brunne, B.4
Bock, H.H.5
Zhao, S.6
Frotscher, M.7
|