Effects of estrogen and gender on cataractogenesis induced by high-let radiation

Radiation Research

Volumn 173, Issue 2, 2010, Pages 191-196

  Henderson, Mark A ^a   Valluri, Shailaja ^a   Garrett, Joy ^a   Lopez, Jennifer T ^a   Caperell Grant, Andrea ^a   Mendonca, Marc S ^a   Rusek, Adam ^b   Bigsby, Robert M ^a   Dynlacht, Joseph R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATARACTOGENESIS; CONTROLLED STUDY; FEMALE; GAMMA RADIATION; GENDER; LINEAR ENERGY TRANSFER; MALE; NONHUMAN; PRIORITY JOURNAL; RADIATION CATARACT; RADIATION DOSE; RAT; SEX DIFFERENCE;

ANIMALS; CATARACT; DISEASE PROGRESSION; ESTRADIOL; FEMALE; LINEAR ENERGY TRANSFER; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS;

ANIMALIA; RATTUS;

EID: 75149129058     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1917.1     Document Type: Article

References (43)

1. F. A. Cucinotta, F. K. Manuel, J. Jones, G. Iszard, J. Murrey, B. Djojonegro and M. Wear, Space radiation and cataracts in astronauts. Radiat. Res. 156, 460-466 (2001).
2. J. A. Jones, M. McCarten, K. Manuel, B. Djojonegoro, J. Murray, A. Feiversen and M. Wear, Cataract formation mechanisms and risk in aviation and space crews. Aviat. Space Environ. Med. 78, A56-A66 (2007).
3. N. Rastegar, P. Eckart and M. Mertz, Radiation-induced cataract in astronauts and cosmonauts. Graefes Arch. Clin. Exp. Ophthalmol. 240, 543-547 (2002).
4. F. O. Aina, L. Smeeth, R. Hubbard, L. S. Hurt and A. E. Fletcher, Hormone replacement therapy and cataract: a population-based case-control study. Eye 20, 417-422 (2006).
5. J. M. Benitez del Castillo, T. del Rio and J. Garcia-Sanchez, Effects of estrogen use on lens transmittance in postmenopausal women. Ophthalmology 104, 970-973 (1997).
6. E. E. Freeman, B. Munoz, O. D. Schein and S. K. West, Hormone replacement therapy and lens opacities: the Salisbury Eye Evaluation project. Arch. Ophthalmol. 119, 1687-1692 (2001).
7. B. E. Klein, R. Klein and L. L. Ritter, Is there evidence of an estrogen effect on age-related lens opacities? The Beaver Dam Eye Study. Arch. Ophthalmol. 112, 85-91 (1994).
8. K. Worzala, R. Hiller, R. D. Sperduto, K. Mutalik, J. M. Murabito, M. Moskowitz, R. B. D'Agostino and P. W. Wilson, Postmenopausal estrogen use, type of menopause, and lens opacities: the Framingham studies. Arch. Intern. Med. 161, 1448-1454 (2001).
9. R. M. Bigsby, H. Cardenas, A. Caperell-Grant and C. J. Grubbs, Protective effects of estrogen in a rat model of age-related cataracts. Proc. Natl. Acad. Sci. USA 96, 9328-9332 (1999).
10. A. M. Hales, C. G. Chamberlain, C. R. Murphy and J. W. McAvoy, Estrogen protects lenses against cataract induced by transforming growth factor-beta (TGFb). J. Exp. Med. 185, 273-280 (1997).
11. J. R. Dynlacht, C. Tyree, S. Valluri, C. DesRosiers, A. Caperell-Grant, M. S. Mendonca, R. Timmerman and R. M. Bigsby, Effect of estrogen on radiation-induced cataractogenesis. Radiat. Res. 165, 9-15 (2006).
12. R. M. Bigsby, S. Valluri, J. Lopez, M. S. Mendonca, A. Caperell-Grant, C. DesRosiers and J. R. Dynlacht, Ovarian hormone modulation of radiation-induced cataractogenesis: dose-response studies. Invest. Ophthalmol. Vis. Sci. 50, 3304-3310 (2009).
13. J. R. Dynlacht, S. Valluri, J. Lopez, F. Greer, C. Desrosiers, A. Caperell-Grant, M. S. Mendonca and R. M. Bigsby, Estrogen protects against radiation-induced cataractogenesis. Radiat. Res. 170, 758-764 (2008).
14. M. A. Henderson, S. Valluri, C. DesRosiers, J. T. Lopez, C. N. Batuello, A. Caperell-Grant, M. S. Mendonca, E. M. Powers, R. M. Bigsby and J. R. Dynlacht, Effect of gender on radiation-induced cataractogenesis. Radiat. Res. 172, 129-133 (2009).
15. S. B. Curtis and J. R. Letaw, Galactic cosmic rays and cell-hit frequencies outside the magnetosphere. Adv. Space Res. 9, 293-298 (1989).
16. C. Medvedovsky, B. V. Worgul, Y. Huang, D. J. Brenner, F. Tao, J. Miller, C. Zeitlin and E. J. Ainsworth, The influence of dose, dose-rate and particle fragmentation on cataract induction by energetic iron ions. Adv. Space Res. 14, 475-482 (1994).
17. R. Steinmetz, N. G. Brown, D. L. Allen, R. M. Bigsby and N. Ben-Jonathan, The environmental estrogen bisphenol A stimulates prolactin release in vitro and in vivo. Endocrinology 138, 1780-1786 (1997).
18. F. J. Rini, B. V. Worgul and G. R. Merriam, Jr., Radiation cataracogenesis in rat lenses. Bull. NY Acad. Med. 62, 744-753 (1986).
19. 1 arrest of cell proliferation in the ocular lens prevents development of radiation cataract. Ophthalmic Res. 14, 215-220 (1982).
20. B. V. Worgul, G. R. Merriam, A. Szechter and D. Srinivasan, Lens epithelium and radiation cataract. I. Preliminary studies. Arch. Ophthalmol. 94, 996-999 (1976).
21. P. J. Leinfelder, T. C. Evans and E. Riley, Production of cataracts in animals by X-rays and fast neutrons. Radiology 65, 433-438 (1955).
22. G. R. Merriam, Jr., B. V. Worgul, C. Medvedovsky, M. Zaider and H. H. Rossi, Accelerated heavy particles and the lens. I. Cataractogenic potential. Radiat. Res. 98, 129-140 (1984).
23. E. S. Gragoudas, K. M. Egan, S. M. Walsh, S. Regan, J. E. Munzenrider and V. Taratuta, Lens changes after proton beam irradiation for uveal melanoma. Am. J. Ophthalmol. 119, 157-164 (1995).
24. D. J. Brenner, C. Medvedovsky, Y. Huang, G. R. Merriam, Jr. and B. V. Worgul, Accelerated heavy particles and the lens. VI. RBE studies at low doses. Radiat. Res. 128, 73-81 (1991).
25. A. B. Cox, E. J. Ainsworth, J. G. Jose, A. C. Lee and J. T. Lett, Cataractogenesis from high-LET radiation and the Casarett model. Adv. Space Res. 3, 211-219 (1983).
26. B. V. Worgul, Cataract analysis and the assessment of radiation risk in space. Adv. Space Res. 6, 285-293 (1986).
27. B. V. Worgul, D. J. Brenner, C. Medvedovsky, G. R. Merriam, Jr. and Y. Huang, Accelerated heavy particles and the lens. VII: The cataractogenic potential of 450 MeV/amu iron ions. Invest. Ophthalmol. Vis. Sci. 34, 184-193 (1993).
28. F. Tao, P. Powers-Risius, E. L. Alpen, C. Medvedovsky, J. David and B. V. Worgul, Radiation effects on late cytopathological parameters in the murine lens relative to particle fluence. Adv. Space Res. 14, 483-491 (1994).
29. 56Fe ions. Radiat. Res. 120, 280-293 (1989).
30. B. V. Worgul, G. R. Merriam, Jr. and C. Medvedovsky, Accelerated heavy particles and the lens II. Cytopathological changes. Invest. Ophthalmol. Vis. Sci. 27, 108-114 (1986).
31. V. C. Yang and E. J. Ainsworth, A histological study on the cataractogenic effects of heavy charged particles. Proc. Natl. Sci. Counc. Repub. China B 11, 18-28 (1987).
32. J. H. Hayden, H. Rothstein, B. V. Worgul and G. R. Merriam, Jr., Hypophysectomy exerts a radioprotective effect on frog lens. Experientia 36, 116-118 (1980).
33. D. S. Holsclaw, G. R. Merriam, Jr., C. Medvedovsky, H. Rothstein and B. V. Worgul, Stationary radiation cataracts: an animal model. Exp. Eye Res. 48, 385-398 (1989).
34. K. J. Mansfield, A. Cerra and C. G. Chamberlain, FGF-2 counteracts loss of TGFb affected cells from rat lens explants: implications for PCO (after cataract). Mol. Vis. 10, 521-532 (2004).
35. W. R. Meacock, D. J. Spalton and M. R. Stanford, Role of cytokines in the pathogenesis of posterior capsule opacification. Br. J. Ophthalmol. 84, 332-336 (2000).
36. N. H. Sachdev, N. Di Girolamo, T. M. Nolan, P. J. McCluskey, D. Wakefield and M. T. Coroneo, Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the human lens: implications for cortical cataract formation. Invest. Ophthalmol. Vis. Sci. 45, 4075-4082 (2004).
37. J. A. West-Mays and G. Pino, Matrix metalloproteinases as mediators of primary and secondary cataracts. Expert Rev. Ophthalmol. 2, 931-938 (2007).
38. P. Y. Chang, K. A. Bjornstad, E. Chang, M. McNamara, M. H. Barcellos-Hoff, S. P. Lin, G. Aragon, J. R. Polansky, G. M. Lui and E. A. Blakely, Particle irradiation induces FGF2 expression in normal human lens cells. Radiat. Res. 154, 477-484 (2000).
39. P. Y. Chang, K. A. Bjornstad, C. J. Rosen, S. Lin and E. A. Blakely, Particle radiation alters expression of matrix metalloproteases resulting in ECM remodeling in human lens cells. Radiat. Environ. Biophys. 46, 187-194 (2007).
40. B. Rydberg, M. Lobrich and P. K. Cooper, Repair of clustered DNA damage caused by high LET radiation in human fibroblasts. Phys. Med. 14 (Suppl. 1), 24-28 (1998).
41. M. Hada and A. G. Georgakilas, Formation of clustered DNA damage after high-LET irradiation: A review. J. Radiat. Res. 49, 203-210 (2008).
42. G. R. Merriam, Jr. and A. Szechter, The effect of age on the radiosensitivity of rat lenses. Trans. Am. Ophthalmol. Soc. 71, 88-110 (1973).
43. P. Sonneveld, E. Peperkamp and D. W. van Bekkum, Incidence of cataracts in rhesus monkeys treated with whole-body irradiation. Radiology 133, 227-229 (1979).