Estrogen protects against radiation-induced cataractogenesis

Radiation Research

Volumn 170, Issue 6, 2008, Pages 758-764

  Dynlacht, Joseph R ^a   Valluri, Shailaja ^a   Lopez, Jennifer ^a   Greer, Falon ^a   DesRosiers, Colleen ^a   Caperell Grant, Andrea ^a   Mendonca, Marc S ^a   Bigsby, Robert M ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATARACT; CATARACTOGENESIS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GAMMA IRRADIATION; IONIZING RADIATION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RADIATION DOSE; RAT;

ANIMALS; CATARACT; ESTROGENS; EYE; FEMALE; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; RADIATION ONCOLOGY; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

RATTUS;

EID: 57149086102     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1416.1     Document Type: Article

References (52)

1. K. B. Gordon, D. H. Char and R. H. Sagerman, Late effects of radiation on the eye and ocular adnexa. Int. J. Radiat. Oncol. Biol. Phys. 31, 1123-1139 (1995).
2. D. Zierhut, F. Lohr, P. Schraube, P. Huber, F. Wenz, R. Haas, D. Fehrentz, M. Flentje, W. Hunstein and M. Wannenmacher, Cataract incidence after total-body irradiation. Int. J. Radiat. Oncol. Biol. Phys. 46, 131-135 (2000).
3. M. L. van Kempen-Harteveld, Y. Belkacemi, H. B. Kal, M. Labopin and F. Frassoni, Dose-effect relationship for cataract induction after single-dose total body irradiation and bone marrow transplantation for acute leukemia. Int. J. Radiat. Oncol. Biol. Phys. 52, 1367-1374 (2002).
4. P. Frisk, H. Hagberg, A. Mandahl, P. Soderberg and G. Lonnerholm, Cataracts after autologous bone marrow transplantation in children. Acta Paediatr. 89, 814-819 (2000).
5. M. L. van Kempen-Harteveld, H. Struikmans, H. B. Kal, I. van der Tweel, M. P. Mourits, L. F. Verdonck, J. Schipper and J. J. Battermann, Cataract-free interval and severity of cataract after total body irradiation and bone marrow transplantation: influence of treatment parameters. Int. J. Radiat. Oncol. Biol. Phys. 48, 807-815 (2000).
6. Z. K. Ferrufino-Ponce and B. A. Henderson, Radiotherapy and cataract formation. Semin. Ophthalmol. 21, 171-180 (2006).
7. Collaborative Ocular Melanoma Study Group, Incidence of cataract and outcomes after cataract surgery in the first 5 years after iodine 125 brachytherapy in the Collaborative Ocular Melanoma Study: COMS Report No. 27. Ophthalmology 114, 1363-1371 (2007).
8. G. R. Merriam, Jr. and E. F. Focht, A clinical study of radiation cataracts and the relationship to dose. Am. J. Roentgenol. Radium Ther. Nucl. Med. 77, 759-785 (1957).
9. K. Neriishi, E. Nakashima, A. Minamoto, S. Fujiwara, M. Akahoshi, H. K. Mishima, T. Kitaoka and R. E. Shore, Postoperative cataract cases among atomic bomb survivors: Radiation dose response and threshold. Radiat. Res. 168, 404-408 (2007).
10. F. A. Cucinotta, F. K. Manuel, J. Jones, G. Iszard, J. Murrey, B. Djojonegro and M. Wear, Space radiation and cataracts in astronauts. Radiat. Res. 156, 460-466 (2001).
11. N. Rastegar, P. Eckart and M. Mertz, Radiation-induced cataract in astronauts and cosmonauts. Graefes. Arch. Clin. Exp. Ophthalmol. 240, 543-547 (2002).
12. G. Brian and H. Taylor, Cataract blindness - challenges for the 21st century. Bull. World Health Org. 79, 249-256 (2001).
13. B. V. Worgul, G. R. Merriam, Jr., A. Szechter and B. D. Srinivasan, Lens epithelium and radiation cataract. Arch. Ophthalmol. 94, 996-999 (1976).
14. F. J. Rini, B. V. Worgul and G. R. Merriam, Jr., Radiation cataractogenesis in rat lenses. Bull. NY Acad. Med. 62, 744-753 (1986).
15. 1 arrest of cell proliferation in the ocular lens prevents development of radiation cataract. Ophthal. Res. 14, 215-220 (1982).
16. A. M. Taylor, D. G. Harnden, C. F. Arlett, S. A. Harcourt, A. R. Lehmann, S. Stevens and B. A. Bridges, Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 258, 427-429 (1975).
17. J. Jose, The role of DNA damage, its repair and its misrepair in the etiology of cataract: a review. Opthal. Res. 10, 52-62 (1978).
18. N. J. Kleiman and A. Spector, DNA single strand breaks in human lens epithelial cells from patients with cataract. Curr. Eye Res. 12, 423-431 (1993).
19. B. V. Worgul, J. David, S. Odrich, G. R. Merriam, Jr., C. Medvedovsky, J. C. Merriam, S. L. Trokel and C. R. Geard, Evidence of genotoxic damage in human cataractous lenses. Mutagenesis 6, 495-499 (1991).
20. E. J. Hall, B. V. Worgul, L. Smilenov, C. D. Elliston and D. J. Brenner, The relative biological effectiveness of densely ionizing heavy-ion radiation for inducing ocular cataracts in wild type versus mice heterozygous for the ATM gene. Radiat. Environ. Biophys. 45, 99-104 (2006).
21. D. Vavvas, N. F. Azar and D. T. Azar, Mechanisms of disease: cataracts. Ophthalmol. Clin. N. Am. 15, 49-60 (2002).
22. B. E. Klein, R. Klein and L. L. Ritter, Is there evidence of an estrogen effect on age-related lens opacities? The Beaver Dam Eye Study. Arch. Ophthalmol. 112, 85-91 (1994).
23. J. M. Benitez del Castillo, T. del Rio and J. Garcia-Sanchez, Effects of estrogen use on lens transmittance in postmenopausal women. Ophthalmology 104, 970-973 (1997).
24. R. G. Cumming and P. Mitchell, Hormone replacement therapy, reproductive factors, and cataract. The Blue Mountains Eye Study. Am. J. Epidemiol. 145, 242-249 (1997).
25. F. O. Aina, L. Smeeth, R. Hubbard, L. S. Hurt and A. E. Fletcher, Hormone replacement therapy and cataract: a population-based case-control study. Eye 20, 417-422 (2006).
26. E. E. Freeman, B. Munoz, O. D. Schein and S. K. West, Hormone replacement therapy and lens opacities: the Salisbury Eye Evaluation project. Arch. Ophthalmol. 119, 1687-1692 (2001).
27. R. Defay, S. Pinchinat, S. Lumbroso, C. Sultan, L. Papoz and C. Delcourt, Relationships between hormonal status and cataract in French postmenopausal women: the POLA study. Ann. Epidemiol. 13, 638-644 (2003).
28. P. Greaves, R. Goonetilleke, G. Nunn, J. Topham and T. Orton, Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Res. 53, 3919-3924 (1993).
29. S. Pyrhonen, R. Valavaara, H. Modig, M. Pawlicki, T. Pienkowski, S, Gundersen, J. Bauer, G. Westman, S. Lundgren and A. Hajba, Comparison of toremifene and tamoxifen in post-menopausal patients with advanced breast cancer: a randomized double-blind, the 'Nordic' phase III study. Br. J. Cancer 76, 270-277 (1997).
30. A. Paganini-Hill and L. J. Clark, Eye problems in breast cancer patients treated with tamoxifen. Breast Cancer Res. Treat. 60, 167-172 (2000).
31. B. D. Bradbury, T. L. Lash, J. A. Kaye and S. S. Jick, Tamoxifen and cataracts: a null association. Breast Cancer Res. Treat. 87, 189-96 (2004).
32. R. M. Bigsby, H. Cardenas, A. Caperell-Grant and C. J. Grubbs, Protective effects of estrogen in a rat model of age-related cataracts. Proc. Natl. Acad. Sci. USA 96, 9328-9332 (1999).
33. A. M. Hales, C. G. Chamberlain, C. R. Murphy and J. W. McAvoy, Estrogen protects lenses against cataract induced by transforming growth factor-β (TGFβ). J. Exp. Med. 185, 273-280 (1997).
34. M. B. Ruiz-Larrea, A. M. Leal, M. Liza, M. Lacort and H. de Groot, Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation of rat liver microsomes. Steroids 59, 383-388 (1994).
35. S. Ayres, M. Tang and M. T. Subbiah, Estradiol-17beta as an antioxidant: some distinct features when compared with common fat-soluble antioxidants. J. Lab. Clin. Med. 128, 367-375 (1996).
36. J. R. Dynlacht, C. Tyree, S. Valluri, C. DesRosiers, A. Caperell-Grant, M. S. Mendonca, R. Timmerman and R. M. Bigsby, Effect of estrogen on radiation-induced cataractogenesis. Radiat. Res. 165, 9-15 (2006).
37. C. DesRosiers, M. S. Mendonca, C. Tyree, V. Moskvin, M. Bank, L. Massaro, R. M. Bigsby, A. Caperell-Grant, S. Valluri and R. Timmerman, Use of the Leksell Gamma Knife for localized small field lens irradiation in rodents. Technol. Cancer Res. Treat. 2, 449-454 (2003).
38. NCRP, Guidance on Radiation Received in Space Activities. Report No. 98, National Council on Radiation Protection and Measurements, Bethesda, MD, 1989.
39. NCRP, Radiation Protection Guidance for Activities in Low-Earth Orbit. Report No. 132, National Council on Radiation Protection and Measurements, Bethesda, MD, 2000.
40. E. F. Riley, A. L. Lindgren, A. L. Andersen, R. C. Miller and E. J. Ainsworth, Relative cataractogenic effects of X rays, fission-spectrum neutrons, and 56Fe particles: A comparison with mitotic effects. Radiat. Res. 125, 298-305 (1991).
41. J. T. Lett, A. B. Cox and A. C. Lee, Some perspectives on cataractogenesis from heavy charged particles. Radiat. Res. 104 (Suppl. 8), S201-S207 (1985).
42. B. V. Worgul, D. J. Brenner, C. Medvedovsky, G. R. Merriam, Jr. and Y. Huang, Accelerated heavy particles and the lens. VII: The cataractogenic potential of 450 MeV/amu iron ions. Invest. Ophthalmol. Vis. Sci. 34, 184-193 (1993).
43. R. L. Sutherland, R. R. Reddel and M. D. Green, Effects of oestrogens on cell proliferation and cell cycle kinetics. A hypothesis on the cell cycle effects of antioestrogens. Eur. J. Cancer. Clin. Oncol. 19, 307-318 (1983).
44. A. Gompel, S. Somai, M. Chaouat, A. Kazem, H. J. Kloosterboer, I. Beusman, P. Forgez, M. Mimoun and W. Rostène, Hormonal regulation of apoptosis in breast cells and tissues. Steroids 65, 593-598 (2000).
45. K. C. Choi, S. K. Kang, C. J. Tai, N. Auersperg and P. C. Leung, Estradiol up-regulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells. Endocrinology 142, 2351-2360 (2001).
46. J. G. Liehr, Is estradiol a genotoxic mutagenic carcinogen? Endocr. Rev. 21, 40-54 (2000).
47. A. N. Moor, S. Gottipati, R. T. Mallet, J. Sun, F. J. Giblin, R. Roque and P. R. Cammarata, A putative mitochondrial mechanism for antioxidative cytoprotection by 17beta-estradiol. Exp. Eye Res. 78, 933-944 (2004).
48. M. Tang and M. T. Subbiah, Estrogens protect against hydrogen peroxide and arachidonic acid induced DNA damage. Biochim. Biophys. Acta 1299, 155-159 (1996).
49. T. Puck, R. Johnson and P. Webb, Mutation inhibition by beta-estradiol after low doses of gamma-irradiation of mammalian cells. Somat. Cell. Mol. Genet. 25, 59-65 (1999).
50. X. Wang, J. W. Simpkins, J. A. Dykens and P. R. Cammarata, Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability. Investigative Ophthalmol. Vis. Sci. 44, 2067-2075 (2003).
51. C. R. Geard and B. V. Worgul, The lens and cataract: clastogenic responses in epithelial cells of the organ-cultured rat lens. Environ. Mutagen. 9, 111-122 (1987).
52. A. Spector, Oxidative stress-induced cataract: mechanism of action. FASEB J. 9, 1173-1182 (1995).