The RCAS-TVA system for introduction of oncogenes into selected somatic mammary epithelial cells in vivo

Journal of Mammary Gland Biology and Neoplasia

Volumn 14, Issue 4, 2009, Pages 405-409

  Reddy, Jay P ^a   Li, Yi ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Breast cancer; Mammary gland; RCAS; Somatic cell; Tva

Indexed keywords

GLYCOPROTEIN; PROTEIN TVA; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AVIAN LEUKOSIS ONCOVIRUS; BREAST CANCER; BREAST EPITHELIUM; GENE EXPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; ONCOGENE; REVIEW; SOMATIC CELL; TUMOR MODEL; VIRAL GENE DELIVERY SYSTEM;

ALPHARETROVIRUS; ANIMALS; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; GENETIC VECTORS; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; ONCOGENES; TRANSFECTION;

EID: 75149113066     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10911-009-9157-1     Document Type: Review

References (23)

1. Z Du Y Li 2007 RCAS-TVA in the mammary gland: an in vivo oncogene screen and a high fidelity model for breast transformation? Cell Cycle 6 7 823 6 1:CAS:528:DC%2BD2sXnvFClu7w%3D 17377492
2. MN Gould 1993 The introduction of activated oncogenes to mammary cells in vivo using retroviral vectors: a new model for the chemoprevention of premalignant and malignant lesions of the breast J Cell Biochem Suppl 17G 66-72 66 72 10.1002/jcb.240531113 1:STN:280:DyaK2c3ns1KhtQ%3D%3D 8007712
3. MJ Federspiel P Bates JA Young HE Varmus SH Hughes 1994 A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors Proc Natl Acad Sci U S A 91 23 11241 5 10.1073/pnas.91.23.11241 1:CAS:528:DyaK2MXitV2rtbw%3D 7972042 (Pubitemid 24349662)
4. EC Holland HE Varmus 1998 Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice Proc Natl Acad Sci U S A 95 3 1218 23 10.1073/pnas.95.3.1218 1:CAS:528: DyaK1cXosFSqtw%3D%3D 9448312 (Pubitemid 28124939)
5. EC Holland Y Li J Celestino C Dai L Schaefer RA Sawaya, et al. 2000 Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo Am J Pathol 157 3 1031 7 1:CAS:528:DC%2BD3cXmvFWqtbg%3D 10980141
6. S Orsulic Y Li RA Soslow LA Vitale-Cross JS Gutkind HE Varmus 2002 Induction of ovarian cancer by defined multiple genetic changes in a mouse model system Cancer Cell 1 1 53 62 10.1016/S1535-6108(01)00002-2 1:CAS:528: DC%2BD38XitlCmsbo%3D 12086888 (Pubitemid 41039176)
7. BC Lewis DS Klimstra HE Varmus 2003 The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer Genes Dev 17 24 3127 38 10.1101/gad.1140403 1:CAS:528:DC%2BD2cXhs1Sgsw%3D%3D 14681205 (Pubitemid 38040775)
8. YC Du BC Lewis D Hanahan H Varmus 2007 Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion PLoS Biol 5 10 2255 69 10.1371/journal.pbio.0050276 1:CAS:528:DC%2BD2sXhsVersrrP (Pubitemid 350035427)
9. B Seidler A Schmidt U Mayr H Nakhai RM Schmid G Schneider, et al. 2008 A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors Proc Natl Acad Sci U S A 105 29 10137 42 10.1073/pnas.0800487105 1:CAS:528:DC%2BD1cXptFOmsbk%3D 18621715
10. BC Lewis DS Klimstra ND Socci S Xu JA Koutcher HE Varmus 2005 The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma Mol Cell Biol 25 4 1228 37 10.1128/MCB.25.4.1228-1237.2005 1:CAS:528:DC%2BD2MXhs1KgsLc%3D 15684377 (Pubitemid 40204903)
11. S Montaner A Sodhi A Molinolo TH Bugge ET Sawai Y He, et al. 2003 Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes Cancer Cell 3 1 23 36 10.1016/S1535-6108(02)00237-4 1:CAS:528:DC%2BD3sXhtFamt7g%3D 12559173 (Pubitemid 37443889)
12. J Sausville AA Molinolo X Cheng J Frampton N Takebe JS Gutkind, et al. 2008 RCAS/SCL-TVA animal model allows targeted delivery of polyoma middle T oncogene to vascular endothelial progenitors in vivo and results in hemangioma development Clin Cancer Res 14 12 3948 55 10.1158/1078-0432.CCR-07-5152 1:CAS:528:DC%2BD1cXntlWrur8%3D 18559617
13. VS Vervoort M Lu F Valencia J Lesperance G Breier R Oshima, et al. 2008 A novel Flk1-TVA transgenic mouse model for gene delivery to angiogenic vasculature Transgenic Res 17 3 403 15 10.1007/s11248-007-9156-1 1:CAS:528:DC%2BD1cXkvV2qs7o%3D 18027100
14. Z Du K Podsypanina H Huang A McGrath MJ Toneff E Bogoslovskaia, et al. 2006 Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models Proc Natl Acad Sci U S A 103 46 17396 401 10.1073/pnas.0608607103 1:CAS:528:DC%2BD28Xht1KqtL7K 17090666 (Pubitemid 44788980)
15. S Siwko W Bu C Gutierrez BC Lewis M Jechlinger B Schaffhausen, et al. 2008 Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors neoplasia 11 7 653 62
16. JP Morton ME Mongeau DS Klimstra JP Morris YC Lee Y Kawaguchi, et al. 2007 Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis Proc Natl Acad Sci U S A 104 12 5103 8 10.1073/pnas.0701158104 1:CAS:528: DC%2BD2sXjvFChu7w%3D 17372229 (Pubitemid 47186183)
17. SH Hughes 2004 The RCAS vector system Folia Biol (Praha) 50 3-4 107 19 1:CAS:528:DC%2BD2cXntFGrsrs%3D
18. CJ Petropoulos SH Hughes 1991 Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells J Virol 65 7 3728 37 1:CAS:528:DyaK3MXksVegu70%3D 2041092
19. SH Hughes JJ Greenhouse CJ Petropoulos P Sutrave 1987 Adaptor plasmids simplify the insertion of foreign DNA into helper- independent retroviral vectors J Virol 61 10 3004 12 1:CAS:528:DyaL2sXls12qsbw%3D 3041020
20. H Kim S You IJ Kim J Farris LK Foster DN Foster 2001 Increased mitochondrial-encoded gene transcription in immortal DF-1 cells Exp Cell Res 265 2 339 47 10.1006/excr.2001.5207 1:CAS:528:DC%2BD3MXis1ertb4%3D 11302700 (Pubitemid 32980223)
21. M Himly DN Foster I Bottoli JS Iacovoni PK Vogt 1998 The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis viruses Virology 248 2 295 304 10.1006/viro.1998.9290 1:CAS:528:DyaK1cXlvVOntrk%3D 9721238 (Pubitemid 28417716)
22. J Schaefer-Klein I Givol EV Barsov JM Whitcomb M VanBrocklin DN Foster, et al. 1998 The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors Virology 248 2 305 11 10.1006/viro.1998.9291 1:CAS:528:DyaK1cXlvVOntL8%3D 9721239 (Pubitemid 28417717)
23. Nguyen D-A, Beeman N, Lewis M, Schaack J, Neville MC. Intraductal injection into the mouse mammary gland. In: Ip MM, Asch BB, editors. Methods in Mammary Gland Biology and Breast Cancer Research. New York: Kluwer Academic; 2000. p. 259-70.