John daly's compound, epibatidine, facilitates identification of nicotinic receptor subtypes

Journal of Molecular Neuroscience

Volumn 40, Issue 1-2, 2010, Pages 96-104

  Marks, Michael J ^a   Laverty, Duncan S ^a   Whiteaker, Paul ^b   Salminen, Outi ^c   Grady, Sharon R ^a   McIntosh, J Michael ^d   Collins, Allan C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b BARROW NEUROLOGICAL INSTITUTE   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Bungarotoxin; Conotoxin MII; Cytisine; Epibatidine; Neuronal nicotinic acetylcholine receptors; Null mutant mice

Indexed keywords

BUNGAROTOXIN RECEPTOR; EPIBATIDINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR ALPHA4BETA2; NICOTINIC RECEPTOR BETA2;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BETA CHAIN; BINDING AFFINITY; BRAIN REGION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BINDING SITE; GENE DELETION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; BRAIN; BRAIN CHEMISTRY; GENE DELETION; MICE; MICE, INBRED C57BL; NICOTINIC AGONISTS; PROTEIN SUBUNITS; PYRIDINES; RECEPTORS, NICOTINIC; SYNAPTIC TRANSMISSION;

MUS;

EID: 75049085112     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-009-9264-x     Document Type: Conference Paper

References (45)

1. 3H]Methylcarbamylcholine, a new radioligand for studying brain nicotinic receptors Biochemical Pharmacology 35 4199 4202 10.1016/0006-2952(86)90695-7 1:CAS:528:DyaL2sXnvFWkug%3D%3D 3790148 (Pubitemid 17204087)
2. MR Adams AL Nikkel DL Donnelly-Roberts AT Watt JF Johnston LM Cowsert M Butler PE Kroeger L Frost P Curzon MW Decker RS Bitner 2004 In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide Brain Research. Molecular Brain Research 129 67 79 10.1016/j.molbrainres.2004.06.019 1:CAS:528:DC%2BD2cXotlCks7k%3D 15469883 (Pubitemid 39304250)
3. 3H] methylcarbamylcholine in rat brain European Journal of Pharmacology 253 261 267 10.1016/0014-2999(94)90200-3 1:CAS:528:DyaK2cXitlKktL4%3D 8200419
4. B Badio JW Daly 1994 Epibatidine, a potent analgetic and nicotinic agonist Molecular Pharmacology 45 563 569 1:CAS:528:DyaK2cXjtFGiu7o%3D 8183234
5. RW Brown AC Collins JM Lindstrom P Whiteaker 2007 Nicotinic alpha5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers Journal of Neurochemistry 103 204 215 1:CAS:528:DC%2BD2sXhtF2qu7bL 17573823
6. N Champtiaux C Gotti M Cordero-Erausquin DJ David C Przybylski C Léna F Clementi M Moretti FM Rossi N Le Novère JM McIntosh AM Gardier JP Changeux 2003 Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice Journal of Neuroscience 23 7820 78299 1:CAS:528:DC%2BD3sXmvFGhtbc%3D 12944511
7. 125I]-alpha-bungarotoxin Journal of Neuroscience 5 1307 1315 1:CAS:528:DyaL2MXktFOgs7s%3D 3998824
8. AC Collins O Salminen MJ Marks P Whiteaker SR Grady 2009 The road to discovery of nicotinic receptor subtypes Handbook of Experimental Pharmacology 192 85 112 10.1007/978-3-540-69248-5-4 19184647
9. WG Conroy DK Berg 1995 Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions Journal of Biological Chemistry 270 4424 4431 10.1074/jbc.270.9.4424 1:CAS:528:DyaK2MXktFSiu78%3D 7876208
10. BC Cox AM Marritt DC Perry KJ Kellar 2008 Transport of multiple nicotinic acetylcholine receptors in the rat optic nerve: High densities of receptors containing alpha6 and beta3 subunits Journal of Neurochemistry 105 1924 1938 10.1111/j.1471-4159.2008.05282.x 1:CAS:528:DC%2BD1cXntVCktbo%3D 18266937 (Pubitemid 351678506)
11. JW Daly GB Brown H Mennah-Dwumah CW Myers 1978 Classification of skin alkaloids from neotropical poison-dart frogs (Dendrobatidae) Toxicon 16 163 188 10.1016/0041-0101(78)90036-3 1:CAS:528:DyaE1MXotFyjtQ%3D%3D 635931
12. 125I]IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors Journal of Pharmacology and Experimental Therapeutics 282 445 451 9223586
13. V Gerzanich X Peng F Wang G Wells R Anand S Fletcher J Lindstrom 1995 Comparative pharmacology of epibatidine: A potent agonist for neuronal nicotinic acetylcholine receptors Molecular Pharmacology 48 774 782 1:CAS:528: DyaK2MXovFajsb8%3D 7476906
14. C Gotti M Moretti A Zanardi A Gaimarri N Champtiaux JP Changeux P Whiteaker MJ Marks F Clementi M Zoli 2005 Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: Identification of a new native nAChR subtype alpha3beta2(alpha5 or beta3) enriched in retinocollicular afferents Molecular Pharmacology 68 1162 1171 10.1124/mol.105.015925 1:CAS:528:DC%2BD2MXhtVyhu7fK 16049166 (Pubitemid 41348716)
15. C Gotti M Moretti F Clementi L Riganti JM McIntosh AC Collins MJ Marks P Whiteaker 2005 Expression of nigrostriatal alpha 6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by beta 3 subunit gene deletion Molecular Pharmacology 67 2007 2015 10.1124/mol.105.011940 1:CAS:528:DC%2BD2MXkvFGisrc%3D 15749993 (Pubitemid 41007782)
16. SR Grady M Moretti M Zoli MJ Marks A Zanardi L Pucci F Clementi C Gotti 2009 Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4and alpha3beta3beta4subtypes mediate acetylcholine release Journal of Neuroscience 29 2272 2282 10.1523/JNEUROSCI.5121-08.2009 1:CAS:528:DC%2BD1MXisV2gsr0%3D 19228980
17. 3H]Epibatidine binding to nicotinic cholinergic receptors in brain Medicinal Chemistry Research 4 538 546 1:CAS:528:DyaK2MXjslSitLo%3D
18. 3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain Molecular Pharmacology 48 280 287 1:CAS:528:DyaK2MXnvVKhs7s%3D 7651361
19. D Mao RP Yasuda H Fan BB Wolfe KJ Kellar 2006 Heterogeneity of nicotinic cholinergic receptors in rat superior cervical and nodose ganglia Molecular Pharmacology 70 1693 1699 10.1124/mol.106.027458 1:CAS:528:DC%2BD28XhtFygsbbL 16882879 (Pubitemid 44776428)
20. MJ Marks AC Collins 1982 Characterization of nicotine binding in mouse brain and comparison with the binding of α-bungarotoxin and quinuclidinyl benzilate Molecular Pharmacology 22 554 564 1:CAS:528:DyaL3sXitFSnu7k%3D 7155123
21. MJ Marks KW Smith AC Collins 1998 Differential agonist inhibition identifies multiple epibatidine binding sites in mouse brain Journal of Pharmacology and Experimental Therapeutics 285 377 386 1:CAS:528: DyaK1cXisVCqt7s%3D 9536034
22. MJ Marks P Whiteaker J Calcaterra JA Stitzel AE Bullock SR Grady MR Picciotto J-P Changeux AC Collins 1999 Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the β2 subunit Journal of Pharmacology and Experimental Therapeutics 289 1090 1103 1:CAS:528:DyaK1MXislGisbw%3D 10215692
23. + efflux in interpeduncular nucleus and inferior colliculus of β2 null mutant mice Journal of Neurochemistry 81 1102 1115 10.1046/j.1471-4159.2002.00910.x 1:CAS:528:DC%2BD38XksV2hs7c%3D 12065623 (Pubitemid 34809293)
24. 3H]epibatidine Molecular Pharmacology 70 947 959 10.1124/mol.106.025338 1:CAS:528:DC%2BD28Xps1Smsb4%3D 16728647 (Pubitemid 44268451)
25. + efflux with high and low sensitivity to stimulation by acetylcholine Neuropharmacology 53 390 405 10.1016/j.neuropharm. 2007.05.021 1:CAS:528:DC%2BD2sXovFers70%3D 17631923 (Pubitemid 47225090)
26. AM Marritt BC Cox RP Yasuda JM McIntosh Y Xiao BB Wolfe KJ Kellar 2005 Nicotinic cholinergic receptors in the rat retina: Simple and mixed heteromeric subtypes Molecular Pharmacology 68 1656 1668 1:CAS:528:DC%2BD2MXht1yksbbJ 16129735
27. 3H](-)nicotine label the same recognition site in brain Molecular Pharmacology 31 169 174 1:CAS:528:DyaL2sXhsFSjurw%3D 3807893
28. LM Marubio M del Mar Arroyo-Jimenez M Cordero-Erausquin C Lena N Le Novere A de Kerchove d'Exaerde M Huchet MI Damaj J-P Changeux 1999 Nature (London) 398 805 810 10.1038/19756 1:CAS:528:DyaK1MXjtVSrsbo%3D (Pubitemid 29205348)
29. NS Millar C Gotti 2008 Diversity of vertebrate nicotinic acetylcholine receptors Neuropharmacology 56 237 246 10.1016/j.neuropharm.2008.07.041 18723036
30. M Moroni R Zwart E Sher BK Cassels I Bermudez 2006 α4β2 nicotinic receptors with high and low acetylcholine sensitivity: Pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine Molecular Pharmacology 70 755 768 10.1124/mol.106.023044 1:CAS:528:DC%2BD28Xnslyjtrk%3D 16720757 (Pubitemid 44092336)
31. A Orr-Urtreger FM Goldner M Saeki T Lorenzo T Goldberg M DeBiasi JA Dani JW Patrick AL Beaudet 1997 Mice deficient in the α7 neuronal nicotinic receptor lack α-bungarotoxin binding sites and hippocampal fast nicotinic currents Journal of Neuroscience 17 9165 9171 1:CAS:528:DyaK2sXnsFWksLg%3D 9364063
32. 3H]Cytisine binding to nicotinic cholinergic receptors in brain Molecular Pharmacology 39 9 12 1:CAS:528:DyaK3MXnsFKmsQ%3D%3D 1987453
33. MJ Parker A Beck CW Leutje 1998 Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity Molecular Pharmacology 54 1132 1139 1:CAS:528:DyaK1MXptVei 9855644
34. J Patrick WB Stallcup 1977 α-Bungarotoxin binding and cholinergic receptor function on a rat sympathetic nerve cell line Journal of Biological Chemistry 252 8629 8633 1:CAS:528:DyaE2sXlvFGju7k%3D 925016
35. 3H]Epibatidine labels nicotinic receptors in rat brain: An autoradiographic study Journal of Pharmacology and Experimental Therapeutics 275 1030 1034 1:CAS:528:DyaK2MXpsF2gsb8%3D 7473129
36. DC Perry Y Xiao HN Nguyen JL Musachio MI Dávila-García KJ Kellar 2002 Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography Journal of Neurochemistry 82 468 481 10.1046/j.1471-4159.2002.00951.x 1:CAS:528:DC%2BD38Xmt1ejs7s%3D 12153472 (Pubitemid 34831488)
37. MR Picciotto M Zoli C Lena A Bessis Y Lallemand N LeNovere P Vincent E Pich P Bruret J-P Changeux 1995 Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain Nature 374 65 67 10.1038/374065a0 1:CAS:528:DyaK2MXktFCrt78%3D 7870173
38. S Pons L Fattore G Cossu S Tolu E Porcu JM McIntosh JP Changeux U Maskos W Fratta 2008 Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration Journal of Neuroscience 28 12318 12327 10.1523/JNEUROSCI.3918-08.2008 1:CAS:528:DC%2BD1cXhsVGmtLjJ 19020025
39. C Romano A Goldstein 1980 Stereospecific nicotine receptors on rat brain membranes Science 210 647 650 10.1126/science.7433991 1:CAS:528:DyaL3MXptg%3D%3D 7433991
40. R Salas KD Cook L Bassetto M De Biasi 2004 The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice Neuropharmacology. 47 401 407 10.1016/j.neuropharm.2004. 05.002 1:CAS:528:DC%2BD2cXmtVCjtbg%3D 15275829 Erratum in: (2004) Neuropharmacology, 47, 1113 (Pubitemid 38953231)
41. O Salminen P Whiteaker SR Grady AC Collins JM McIntosh MJ Marks 2005 The subunit composition and pharmacology of alpha-conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay Neuropharmacology 48 696 705 10.1016/j.neuropharm.2004.12.011 1:CAS:528:DC%2BD2MXjt1KhtLk%3D 15814104 (Pubitemid 40462409)
42. O Salminen JA Drapeau JM McIntosh AC Collins MJ Marks SR Grady 2007 Pharmacology of α-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice Molecular Pharmacology 71 1563 1571 10.1124/mol.106.031492 1:CAS:528:DC%2BD2sXmt1WqtLs%3D 17341654 (Pubitemid 47010909)
43. 125I]- epibatidine British Journal of Pharmacology 131 729 739 10.1038/sj.bjp.0703616 1:CAS:528:DC%2BD3cXnvVGiurw%3D 11030722
44. P Whiteaker CG Peterson W Xu JM McIntosh R Paylor AL Beaudet AC Collins MJ Marks 2002 Involvement of the alpha3 subunit in central nicotinic binding populations Journal of Neuroscience 22 2522 2529 1:CAS:528:DC%2BD38XisF2gurg%3D 11923417
45. M Zoli C Lena MR Picciotto J-P Changeux 1998 Identification of four classes of nicotinic receptors using beta2 mutant mice Journal of Neuroscience 18 4461 4472 1:CAS:528:DyaK1cXjslGjsLk%3D 9614223