The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond

Biochemistry

Volumn 49, Issue 3, 2010, Pages 470-477

  Zornetzer, Gregory A ^a,b   Tanem, Justinn ^a,c   Fox, Brian G ^a   Markley, John L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEINS; ACYL-ACP; BIPHASIC; CONFORMATIONAL FLEXIBILITY; DYNAMIC MOTIONS; EXCHANGE RATES; FATTY ACID BINDING; FATTY ACID BIOSYNTHESIS; LINEAR CORRELATION; NMR STRUCTURES; NMR STUDIES; POSITIVE CORRELATIONS; PROTEIN MOTION; RELAXATION DISPERSION; THIOESTERS; TIME-SCALES; TWO-STATE MODEL;

ACIDS; BIOCHEMISTRY; DISPERSIONS; FATTY ACIDS; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

PROTEINS;

ACYL CARRIER PROTEIN; FATTY ACID; NITROGEN 15; SOLVENT; THIOESTER;

ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CONFORMATION; CORRELATION ANALYSIS; DYNAMICS; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

ACYL CARRIER PROTEIN; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; FATTY ACIDS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION;

EID: 74949114946     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9014659     Document Type: Article

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