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Volumn 170, Issue 2, 2010, Pages 108-111

Functional genetic analysis of the Plasmodium falciparum deoxyxylulose 5-phosphate reductoisomerase gene

Author keywords

Drug targets; Isoprenoid biosynthesis; Malaria

Indexed keywords

DEOXYXYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; OXIDOREDUCTASE; PLASMID DNA; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

EID: 74849090103     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.12.001     Document Type: Article
Times cited : (60)

References (19)
  • 1
    • 34547609909 scopus 로고    scopus 로고
    • The non-mevalonate pathway of isoprenoid precursor biosynthesis
    • Hunter W.N. The non-mevalonate pathway of isoprenoid precursor biosynthesis. J Biol Chem 282 (2007) 21573-21577
    • (2007) J Biol Chem , vol.282 , pp. 21573-21577
    • Hunter, W.N.1
  • 2
    • 34250785114 scopus 로고    scopus 로고
    • The function of terpene natural products in the natural world
    • Gershenzon J., and Dudareva N. The function of terpene natural products in the natural world. Nat Chem Biol 3 (2007) 408-414
    • (2007) Nat Chem Biol , vol.3 , pp. 408-414
    • Gershenzon, J.1    Dudareva, N.2
  • 3
    • 0033520336 scopus 로고    scopus 로고
    • Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs
    • Jomaa H., Wiesner J., Sanderbrand S., et al. Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science 285 (1999) 1573-1576
    • (1999) Science , vol.285 , pp. 1573-1576
    • Jomaa, H.1    Wiesner, J.2    Sanderbrand, S.3
  • 4
    • 10644295471 scopus 로고    scopus 로고
    • The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum
    • Cassera M.B., Gozzo F.C., D'Alexandri F.L., et al. The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum. J Biol Chem 279 (2004) 51749-51759
    • (2004) J Biol Chem , vol.279 , pp. 51749-51759
    • Cassera, M.B.1    Gozzo, F.C.2    D'Alexandri, F.L.3
  • 5
    • 0034845931 scopus 로고    scopus 로고
    • Biosynthesis of terpenoids. 2C-Methyl-d-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum
    • Rohdich F., Eisenreich W., Wungsintaweekul J., Hecht S., Schuhr C.A., and Bacher A. Biosynthesis of terpenoids. 2C-Methyl-d-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum. Eur J Biochem 268 (2001) 3190-3197
    • (2001) Eur J Biochem , vol.268 , pp. 3190-3197
    • Rohdich, F.1    Eisenreich, W.2    Wungsintaweekul, J.3    Hecht, S.4    Schuhr, C.A.5    Bacher, A.6
  • 6
    • 0033109071 scopus 로고    scopus 로고
    • Construction and characterization of Escherichia coli disruptants defective in the yaeM gene
    • Kuzuyama T., Takahashi S., and Seto H. Construction and characterization of Escherichia coli disruptants defective in the yaeM gene. Biosci Biotechnol Biochem 63 (1999) 776-778
    • (1999) Biosci Biotechnol Biochem , vol.63 , pp. 776-778
    • Kuzuyama, T.1    Takahashi, S.2    Seto, H.3
  • 9
    • 34848824360 scopus 로고    scopus 로고
    • Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-d-xylulose 5-phosphate reductoisomerase
    • Tahar R., and Basco L.K. Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-d-xylulose 5-phosphate reductoisomerase. Am J Trop Med Hyg 77 (2007) 214-220
    • (2007) Am J Trop Med Hyg , vol.77 , pp. 214-220
    • Tahar, R.1    Basco, L.K.2
  • 10
    • 40949137369 scopus 로고    scopus 로고
    • Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates
    • Haemers T., Wiesner J., Giessmann D., et al. Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates. Bioorg Med Chem 16 (2008) 3361-3371
    • (2008) Bioorg Med Chem , vol.16 , pp. 3361-3371
    • Haemers, T.1    Wiesner, J.2    Giessmann, D.3
  • 11
    • 37349048178 scopus 로고    scopus 로고
    • gamma-Substituted bis(pivaloyloxymethyl)ester analogues of fosmidomycin and FR900098
    • Kurz T., Behrendt C., Pein M., Kaula U., Bergmann B., and Walter R.D. gamma-Substituted bis(pivaloyloxymethyl)ester analogues of fosmidomycin and FR900098. Arch Pharm (Weinheim) 340 (2007) 661-666
    • (2007) Arch Pharm (Weinheim) , vol.340 , pp. 661-666
    • Kurz, T.1    Behrendt, C.2    Pein, M.3    Kaula, U.4    Bergmann, B.5    Walter, R.D.6
  • 12
    • 37349115214 scopus 로고    scopus 로고
    • Double ester prodrugs of FR900098 display enhanced in vitro antimalarial activity
    • Wiesner J., Ortmann R., Jomaa H., and Schlitzer M. Double ester prodrugs of FR900098 display enhanced in vitro antimalarial activity. Arch Pharm (Weinheim) 340 (2007) 667-669
    • (2007) Arch Pharm (Weinheim) , vol.340 , pp. 667-669
    • Wiesner, J.1    Ortmann, R.2    Jomaa, H.3    Schlitzer, M.4
  • 13
    • 34748895608 scopus 로고    scopus 로고
    • Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues
    • Ortmann R., Wiesner J., Silber K., Klebe G., Jomaa H., and Schlitzer M. Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues. Arch Pharm (Weinheim) 340 (2007) 483-490
    • (2007) Arch Pharm (Weinheim) , vol.340 , pp. 483-490
    • Ortmann, R.1    Wiesner, J.2    Silber, K.3    Klebe, G.4    Jomaa, H.5    Schlitzer, M.6
  • 14
    • 34249895597 scopus 로고    scopus 로고
    • Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum
    • Cassera M.B., Merino E.F., Peres V.J., Kimura E.A., Wunderlich G., and Katzin A.M. Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. Mem Inst Oswaldo Cruz 102 (2007) 377-383
    • (2007) Mem Inst Oswaldo Cruz , vol.102 , pp. 377-383
    • Cassera, M.B.1    Merino, E.F.2    Peres, V.J.3    Kimura, E.A.4    Wunderlich, G.5    Katzin, A.M.6
  • 15
    • 23744435838 scopus 로고    scopus 로고
    • pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
    • Sidhu A.B., Valderramos S.G., and Fidock D.A. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol Microbiol 57 (2005) 913-926
    • (2005) Mol Microbiol , vol.57 , pp. 913-926
    • Sidhu, A.B.1    Valderramos, S.G.2    Fidock, D.A.3
  • 16
    • 8644261622 scopus 로고    scopus 로고
    • 1-Deoxy-d-xylulose 5-phosphate reductoisomerase: an overview
    • Proteau P.J. 1-Deoxy-d-xylulose 5-phosphate reductoisomerase: an overview. Bioorg Chem 32 (2004) 483-493
    • (2004) Bioorg Chem , vol.32 , pp. 483-493
    • Proteau, P.J.1
  • 17
    • 44849135047 scopus 로고    scopus 로고
    • Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake
    • Brown A.C., and Parish T. Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake. BMC Microbiol 8 (2008) 78
    • (2008) BMC Microbiol , vol.8 , pp. 78
    • Brown, A.C.1    Parish, T.2
  • 19
    • 0037154255 scopus 로고    scopus 로고
    • A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae
    • Akerley B.J., Rubin E.J., Novick V.L., Amaya K., Judson N., and Mekalanos J.J. A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc Natl Acad Sci USA 99 (2002) 966-971
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 966-971
    • Akerley, B.J.1    Rubin, E.J.2    Novick, V.L.3    Amaya, K.4    Judson, N.5    Mekalanos, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.