Altered expression of cytokines and sex steroid receptors in the reproductive tract of cysticercotic male mice

Parasite Immunology

Volumn 32, Issue 2, 2010, Pages 91-100

  RodrIguez Dorantes M ^a,b   LOpez Griego L ^a   ZarazUa Cruz C M ^a   Morales Montor, J ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b Instituto Nacional de Medicina Genómica   (Germany)

Author keywords

Cysticercosis; Cytokines; Feminization; Helminth infection; Immunoendocrine; Steroidogenesis

Indexed keywords

ANDROGEN RECEPTOR; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; SEX HORMONE; SEX STEROID RECEPTOR; STEROID RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; CONTROLLED STUDY; CYSTICERCOSIS; CYTOKINE PRODUCTION; GENE EXPRESSION; GENITAL SYSTEM; HOST; HOST PATHOGEN INTERACTION; MALE; MOUSE; NONHUMAN; PARASITE; PRIORITY JOURNAL; REPRODUCTION; SEMINAL VESICLE; STEROID BLOOD LEVEL; STEROIDOGENESIS; TAENIA CRASSICEPS; TESTIS;

ANIMALS; CYSTICERCOSIS; CYTOKINES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENITALIA, MALE; MALE; MICE; MICE, INBRED BALB C; RECEPTORS, STEROID; TAENIA; UP-REGULATION;

MUS; TAENIA CRASSICEPS; VERMES;

EID: 74549196940     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2009.01166.x     Document Type: Article

References (43)

1. Besedovsky HO Del Rey A. The cytokine-HPA axis feed-back circuit. Z Rheumatol 2000 59 : 26 30.
2. Buckingham JC, Loxley HD, Christian HC Philip JG. Activation of the HPA axis by immune insults: roles and interactions of cytokines, eicosanoids, glucocorticoids. Pharmacol Biochem Behav 1996 54 : 285 298.
3. Grossman CJ Roselle GA. The interrelationship of the HPG-thymic axis and immune system regulation. J Steroid Biochem 1983 19 : 461 467.
4. Beckage NE. Host parasite hormonal relationships: a common theme? Exp Parasitol 1991 72 : 332 338.
5. Lin YC, Kikihisha Y, Kono H Gu Y. Effects of larval tapeworm of (Teania taeniformis) on reproductive functions in male and female host rats. Exp Parasitol 1990 70 : 344 352.
6. Sciutto E, Fragoso G, Diaz ML, et al. Murine Taenia crassiceps cysticercosis: H-2 complex and sex influence on susceptibility. Parasitol Res 1991 77 : 243 246.
7. Larralde C, Morales J, Terrazas I, Govezensky T Romano MC. Sex hormone changes induced by the parasite lead to feminization of the male host in murine Taenia crassiceps cysticercosis. J Steroid Biochem Mol Biol 1995 52 : 575 580.
8. Morales-Montor J, Larralde C, Arteaga M, Govezensky T, Romano MC Moralí G. Inhibition of sexual behaviour in male mice infected with Taenia crassiceps cysticerci. J Parasitol 1996 82 : 689 693.
9. Morales-Montor J, Rodríguez-Dorantes M Cerbón MA. Modified expression of steroid 5 alpha-reductase as well as aromatase, but not cholesterol side-chain cleavage enzyme, in the reproductive system of male mice during (Taenia crassiceps) cysticercosis. Parasitol Res 1999 85 : 393 398.
10. Pfaff DW, Schwartz-Giblin S, McCarthy MM Kow L-M. Cellular and molecular mechanisms of female reproductive behaviors. In Neill JD Knobil E (eds The Physiology of Reproduction 1994 2 : 107 220. Raven Press, New York.
11. Tollan-Allerand CD. Estrogen and the brain: beyond ER-a and ER-b experimental. Gerontology 2004 39 : 1579 1586.
12. Romano GJ, Krust A Pfaff DW. Expression and androgen regulation of progesterone receTPor mRNA in neurons of the mediobasal hypothalamus: an in situ hybridization study. Mol Endocrinol 1989 3 : 1295 1300.
13. Olster DH Auerbach ID. Deficits in progesterone-facilitated sexual behaviors and forebrain estrogen and progestin receptors in obese female Zucker rats. Neuroendocrinology 2000 72 : 350 359.
14. Rodríguez-Dorantes M, Cerbón MA, Larralde C Morales-Montor J. Modified progesterone receptor expression in the hypothalamus of cysticercotic male mice. Acta Trop 2007 103 : 123 132.
15. Custodia-Lora N Callard IP. Progesterone and progesterone receptors in reptiles. Gen Comp Endocrinol 2002 127 : 1 7.
16. Paredes RG. Medial preoptic area/anterior hypothalamus and sexual motivation. Scand J Psychol 2003 44 : 203 212.
17. Matthews J Gustafsson JA. Estrogen signaling: a subtle balance between ER alpha and ER beta. Mol Interv 2003 3 : 281 292.
18. Vassilopoulou-Sellin R. Endocrine effects of cytokines. Oncology 1994 8 : 43 46.
19. Svechnikov K, Stocco DM Söder O. Interleukin-1alpha stimulates steroidogenic acute regulatory protein expression via p38 MAP kinase in immature rat Leydig cells. J Mol Endocrinol 2003 30 : 59 67.
20. Tsujishita Y Hurley JH. Structure and lipid transport mechanism of a StAR-related domain. Nat Struct Biol 2000 7 : 408 414.
21. Jäättelä M, Ilvesmäki V, Voutilainen R, Stenman UH Saksela E. Tumor necrosis factor as a potent inhibitor of adrenocorticotropin- induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells. Endocrinology 1991 128 : 623 629.
22. Orava M, Voutilainen R Vihko R. Interferon-gamma inhibits steroidogenesis and accumulation of mRNA of the steroidogenic enzymes P450scc and P450c17 in cultured porcine Leydig cells. Mol Endocrinol 1989 3 : 887 894.
23. Herrmann M, Scholmerich J Straub RH. Influence of cytokines and growth factors on distinct steroidogenic enzymes in vitro: a short tabular data collection. Ann N Y Acad Sci 2002 966 : 166 186.
24. Li X, Youngblood GL, Payne AH Hales DB. Tumor necrosis factor-alpha inhibition of 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) expression. Endocrinology 1995 136 : 3519 3526.
25. Freeman RS. Studies on the biology of Taenia crassiceps (Zeder 1800) Rudolphi, 1810 (Cestoda). Can J Zool 1962 40 : 969 990.
26. Morales-Montor J, Baig S, Mitchell R, Deway K, Hallal-Calleros C Damian RT. Immunoendocrine interactions during chronic cysticercosis determine male mouse feminization: role of IL-6. 1. J Immunol 2001 167 : 4527 4533.
27. Morales-Montor J, Gamboa-Domínguez A, Rodríguez-Dorantes M Cerbón MA. Tissue damage in the male murine reproductive system during experimental Taenia crassiceps cysticercosis. J Parasitol 1999 85 : 887 890.
28. Morales-Montor J, Hallal-Calleros C, Romano M Damian RT. Inhibition of P-450 aromatase prevents feminisation & induces protection during cysticercosis. Int J Parasitol 2002 32 : 1379 1387.
29. Morales-Montor J, Baig S, Hallal-Calleros C Damian RT. Taenia crassiceps: androgen reconstitution of the host leads to protection during cysticercosis. Exp Parasitol 2002 100 : 209 216.
30. Hull EM, Du J, Lorrain DS Matuszewich L. Testosterone, preoptic dopamine, and copulation in male rats. Brain Res Bull 1997 44 : 327 333.
31. Olster DH Blaustein JD. Development of oestradiol-induced progestin receptor immunoreactivity in the hipothalamus of female guinea pigs. J Neurobiol 1991 22 : 195 203.
32. Luttge WG Hall NR. Androgen-induced agonistic behavior in castrate male Swiss-Webster mice: comparison of four naturally occurring androgens. Behav Biol 1973 8 : 725 732.
33. Ogawa S, Chan J, Chester AE, Gustafsson JA, Korach KS Pfaff DW. Survival of reproductive behaviors in estrogen receptor beta gene-deficient (betaERKO) male and female mice. Proc Natl Acad Sci USA 1999 96 : 12887 12892.
34. Temple JL, Fugger HN, Li X, Shetty SJ, Gustafsson J Rissman EF. Estrogen receptor beta regulates sexually dimorphic neural responses to oestradiol. Endocrinology 2001 142 : 510 513.
35. Nomura M, McKenna E, Korach KS, Pfaff DW Ogawa S. Estrogen receptor-beta regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice. Brain Res Mol 2002 109 : 84 94.
36. Shughrue PJ, Lane MV, Scrino PJ Merchenthaler I. Comparative distribution of estrogen receptor-alpha and beta mRNA in the rat pituitary, gonad, and reproductive tract. Steroids 1998 63 : 498 504.
37. Morales J, Velasco T, Tovar V, et al. Castration and pregnancy of rural pigs significantly increase the prevalence of naturally acquired Taenia solium cysticercosis. Vet Parasitol 2002 108 : 41 48.
38. Lin YM, Liu MY, Poon SL, Leu SF Huang BM. Gonadotrophin-releasing hormone-I and -II stimulate steroidogenesis in prepubertal murine Leydig cells in vitro. Asian J Androl 2008 10 : 929 936.
39. Arai KY, Roby KF Terranova PF. Tumor necrosis factor alpha (TNF) suppresses cAMP response element (CRE) activity and nuclear CRE binding protein in MA-10 mouse Leydig tumor cells. Endocrine 2005 27 : 17 24.
40. Hong CY, Park JH, Ahn RS, et al. Molecular mechanism of suppression of testicular steroidogenesis by proinflammatory cytokine tumor necrosis factor alpha 1. Mol Cell Biol 2004 24 : 2593 2604.
41. Paredes RG, Highland L Karam P. Sociosexual behavior in male rats after lesions of the medial preoptic area: evidence for reduced sexual motivation. Brain Res 1993 618 : 271 276.
42. McEwan IJ. Molecular mechanisms of androgen receptor-mediated gene regulation: structure-function analysis of the AF-1 domain. Endocr Relat Cancer 2004 11 : 281 293.
43. Harding SM McGinnis MY. Androgen receptor blockade in the MPOA or VNM: effects on male sociosexual behaviors. Physiol Behav 2004 81 : 671 680.