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Volumn 31, Issue 1, 2010, Pages 102-110

HIF-1α links β-adrenoceptor agonists and pancreatic cancer cells under normoxic condition

Author keywords

adrenergic receptor; Akt; Epidermal growth factor receptor; ERK1 2; Hypothalamic pituitary adrenal axis; Hypoxia inducible factor 1 ; Pancreatic cancer; Protein kinase A

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHEMOKINE RECEPTOR CXCR4; CYCLIC AMP; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FORSKOLIN; GELATINASE B; GLUCOSE TRANSPORTER 1; ISOPRENALINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; PROTEIN KINASE B; SALBUTAMOL; SMALL INTERFERING RNA; VASCULOTROPIN; XAMOTEROL; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

EID: 74549184487     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.181     Document Type: Article
Times cited : (30)

References (30)
  • 1
    • 33746851955 scopus 로고    scopus 로고
    • Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
    • Thaker PH, Han LY, Kamat AA, Arevalo JM, Takahashi R, Lu CH, et al. Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med 2006; 12: 939-944
    • (2006) Nat Med , vol.12 , pp. 939-944
    • Thaker, P.H.1    Han, L.Y.2    Kamat, A.A.3    Arevalo, J.M.4    Takahashi, R.5    Lu, C.H.6
  • 2
    • 45549108603 scopus 로고    scopus 로고
    • Insights into signaling from the β2-adrenergic receptor structure
    • Audet M, Bouvier M. Insights into signaling from the β2-adrenergic receptor structure. Nat Chem Biol 2008; 4: 397-403.
    • (2008) Nat Chem Biol , vol.4 , pp. 397-403
    • Audet, M.1    Bouvier, M.2
  • 3
    • 33847780915 scopus 로고    scopus 로고
    • The neuroendocrine impact of chronic stress on cancer
    • Thaker PH, Lutgendorf SK, Sood AK. The neuroendocrine impact of chronic stress on cancer. Cell Cycle 2007; 6: 430-433
    • (2007) Cell Cycle , vol.6 , pp. 430-433
    • Thaker, P.H.1    Lutgendorf, S.K.2    Sood, A.K.3
  • 4
    • 0035098423 scopus 로고    scopus 로고
    • β-Adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas
    • Weddle DL, Tithoff P, Williams M, Schuller HM. β-Adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas. Carcinogenesis 2001; 22: 473-479
    • (2001) Carcinogenesis , vol.22 , pp. 473-479
    • Weddle, D.L.1    Tithoff, P.2    Williams, M.3    Schuller, H.M.4
  • 5
    • 27144434360 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone stimulates proliferation of immortalized human pancreatic duct epithelia through β-adrenergic transactivation of EGF receptors
    • Askari MD, Tsao MS, Schuller HM. The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through β-adrenergic transactivation of EGF receptors. J Cancer Res Clin Oncol 2005; 131: 639-648
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 639-648
    • Askari, M.D.1    Tsao, M.S.2    Schuller, H.M.3
  • 6
    • 45849103828 scopus 로고    scopus 로고
    • Effects of α-adrenoreceptor antagonists on apoptosis and proliferation of pancreatic cancer cells in vitro
    • Shen SG, Zhang D, Hu HT, Li JH, Wang Z, Ma QY. Effects of α-adrenoreceptor antagonists on apoptosis and proliferation of pancreatic cancer cells in vitro. World J Gastroenterol 2008; 14: 2358-2363
    • (2008) World J Gastroenterol , vol.14 , pp. 2358-2363
    • Shen, S.G.1    Zhang, D.2    Hu, H.T.3    Li, J.H.4    Wang, Z.5    Ma, Q.Y.6
  • 7
    • 0036710591 scopus 로고    scopus 로고
    • Signal transduction to hypoxia-inducible factor-1
    • Semenza GL. Signal transduction to hypoxia-inducible factor-1. Biochemical Pharmacol 2002; 64: 993-998
    • (2002) Biochemical Pharmacol , vol.64 , pp. 993-998
    • Semenza, G.L.1
  • 8
    • 33646707041 scopus 로고    scopus 로고
    • Effect of antisense hypoxiainducible factor 1- on progression, metastasis, and chemosensitivity of pancreatic cancer
    • Chang Q, Qin RY, Huang T, Gao J, Feng YP. Effect of antisense hypoxiainducible factor 1- on progression, metastasis, and chemosensitivity of pancreatic cancer. Pancreas 2006; 32: 297-305.
    • (2006) Pancreas , vol.32 , pp. 297-305
    • Chang, Q.1    Qin, R.Y.2    Huang, T.3    Gao, J.4    Feng, Y.P.5
  • 9
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev 2003; 3: 721-732
    • (2003) Nat Rev , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 10
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia-inducible factor-1 renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura N, Kobayashi M, Horiuchi I, Suzuki A, Wang JX, Chen J, et al. Constitutive expression of hypoxia-inducible factor-1 renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res 2001; 61: 6548-6554
    • (2001) Cancer Res , vol.61 , pp. 6548-6554
    • Akakura, N.1    Kobayashi, M.2    Horiuchi, I.3    Suzuki, A.4    Wang, J.X.5    Chen, J.6
  • 11
    • 20444380009 scopus 로고    scopus 로고
    • NNK-induced hamster lung denocarcinomas over-express β2-adrenergic and EGFR signaling pathways
    • Schuller HM, Cekanova M. NNK-induced hamster lung denocarcinomas over-express β2-adrenergic and EGFR signaling pathways. Lung Cancer 2005; 49: 35-45.
    • (2005) Lung Cancer , vol.49 , pp. 35-45
    • Schuller, H.M.1    Cekanova, M.2
  • 12
    • 20244388286 scopus 로고    scopus 로고
    • Activation of PI3K-Akt pathway mediates antiapoptotic effects of β-adrenergic agonist in airway eosinophils
    • Machida K, Inoue H, Matsumoto K, Tsuda M, Fukuyama S, Koto H, et al. Activation of PI3K-Akt pathway mediates antiapoptotic effects of β-adrenergic agonist in airway eosinophils. Am J Physiol Lung Cell Mol Physiol 2005; 288: 860-867
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. 860-867
    • MacHida, K.1    Inoue, H.2    Matsumoto, K.3    Tsuda, M.4    Fukuyama, S.5    Koto, H.6
  • 13
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510-5514
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 14
    • 27644477840 scopus 로고    scopus 로고
    • Effect of low glutamine/glucose on hypoxia-induced elevation of hypoxia-inducible factor-1alpha in human pancreatic cancer MiaPaCa-2 and human prostatic cancer DU-145 cells
    • Kwon SJ, Lee YJ. Effect of low glutamine/glucose on hypoxia-induced elevation of hypoxia-inducible factor-1alpha in human pancreatic cancer MiaPaCa-2 and human prostatic cancer DU-145 cells. Clin Cancer Res 2005; 11: 4694-4700
    • (2005) Clin Cancer Res , vol.11 , pp. 4694-4700
    • Kwon, S.J.1    Lee, Y.J.2
  • 15
    • 33745259854 scopus 로고    scopus 로고
    • Hypoxia upregulates hypoxia inducible factor (HIF)-3- expression in lung epithelial cells: Characterization and comparison with HIF-1α
    • Li QF, Wang XR, Yang YW, Lin H. Hypoxia upregulates hypoxia inducible factor (HIF)-3- expression in lung epithelial cells: characterization and comparison with HIF-1α. Cell Res 2006; 16: 548-558
    • (2006) Cell Res , vol.16 , pp. 548-558
    • Li, Q.F.1    Wang, X.R.2    Yang, Y.W.3    Lin, H.4
  • 16
    • 33750619348 scopus 로고    scopus 로고
    • Glucose metabolism and cancer
    • Shaw RJ. Glucose metabolism and cancer. Curr Opin Cell Biol 2006; 18: 598-608.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 598-608
    • Shaw, R.J.1
  • 18
    • 0141818115 scopus 로고    scopus 로고
    • Hypoxia induces an autocrine-paracrine survival pathway via plateletderived growth factor (PDGF)-B/PDGF-β receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells
    • Zhang SX, Gozal D, Sachleben LR Jr, Rane M, Klein JB, Gozal E. Hypoxia induces an autocrine-paracrine survival pathway via plateletderived growth factor (PDGF)-B/PDGF-β receptor/ phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells. FASEB J 2003; 17: 1709-1711
    • (2003) FASEB J , vol.17 , pp. 1709-1711
    • Zhang, S.X.1    Gozal, D.2    Sachleben Jr., L.R.3    Rane, M.4    Klein, J.B.5    Gozal, E.6
  • 19
    • 0033981845 scopus 로고    scopus 로고
    • ERK activation upon hypoxia: Involvement in HIF-1 activation
    • Minet E, Arnould T, Michel G, Roland I. ERK activation upon hypoxia: involvement in HIF-1 activation. FEBS Lett 2000; 468: 53-58
    • (2000) FEBS Lett , vol.468 , pp. 53-58
    • Minet, E.1    Arnould, T.2    Michel, G.3    Roland, I.4
  • 20
    • 34848866530 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation stimulates proliferation through PKC-dependent activation of ERK and akt in mouse neural progenitor cells
    • Sung SM, Jung DS, Kwon CH, Park JY, Kang SK, Kim YK. Hypoxia/ reoxygenation stimulates proliferation through PKC-dependent activation of ERK and akt in mouse neural progenitor cells. Neurochem Res 2007; 32: 1932-1939
    • (2007) Neurochem Res , vol.32 , pp. 1932-1939
    • Sung, S.M.1    Jung, D.S.2    Kwon, C.H.3    Park, J.Y.4    Kang, S.K.5    Kim, Y.K.6
  • 21
    • 0036569941 scopus 로고    scopus 로고
    • Hypoxia-inducible factors hif-1- and hif-2- in head and neck cancer: Relationship to tumor biology and treatment outcome in surgically resected patients
    • Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, et al. Hypoxia-inducible factors hif-1- and hif-2- in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res 2002; 62: 2493-2497
    • (2002) Cancer Res , vol.62 , pp. 2493-2497
    • Beasley, N.J.1    Leek, R.2    Alam, M.3    Turley, H.4    Cox, G.J.5    Gatter, K.6
  • 22
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal axis and immunemediated inflammation
    • Chrousos GP. The hypothalamic-pituitary-adrenal axis and immunemediated inflammation. N Engl J Med 1995; 332: 1351-1362
    • (1995) N Engl J Med , vol.332 , pp. 1351-1362
    • Chrousos, G.P.1
  • 23
    • 14944351958 scopus 로고    scopus 로고
    • Stress-induced immune dysfunction: Implications for health
    • Glaser R, Kiecolt-Glaser JK. Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 2005; 5: 243-251
    • (2005) Nat Rev Immunol , vol.5 , pp. 243-251
    • Glaser, R.1    Kiecolt-Glaser, J.K.2
  • 25
    • 39049158404 scopus 로고    scopus 로고
    • GABAB receptor is a novel drug target for pancreatic cancer
    • Schuller HM, AI-Wadei HAN, Majidi M. GABAB receptor is a novel drug target for pancreatic cancer. Am Cancer Soc 2008; 112: 767-777
    • (2008) Am Cancer Soc , vol.112 , pp. 767-777
    • Schuller, H.M.1    Ai-Wadei, H.A.N.2    Majidi, M.3
  • 26
    • 34249931195 scopus 로고    scopus 로고
    • A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway
    • Carie AE, Sebti SM. A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway. Oncogene 2007; 26: 3777-3788
    • (2007) Oncogene , vol.26 , pp. 3777-3788
    • Carie, A.E.1    Sebti, S.M.2
  • 27
    • 33847316161 scopus 로고    scopus 로고
    • Functional role of beta-adrenergic receptors in mitogenic action of nicotine on gastric cancer cells
    • Shin VY, Wu WK, Chu KM, Koo MW, Wong HP, Lam EK, et al. Functional role of beta-adrenergic receptors in mitogenic action of nicotine on gastric cancer cells. Toxicol Sci 2006; 96: 21-29
    • (2006) Toxicol Sci , vol.96 , pp. 21-29
    • Shin, V.Y.1    Wu, W.K.2    Chu, K.M.3    Koo, M.W.4    Wong, H.P.5    Lam, E.K.6
  • 28
    • 0036597698 scopus 로고    scopus 로고
    • Mechanisms of smoking related lung and pancreatic adenocarcinoma development
    • Schuller HM. Mechanisms of smoking related lung and pancreatic adenocarcinoma development. Nat Rev Cancer 2002; 2: 455-463
    • (2002) Nat Rev Cancer , vol.2 , pp. 455-463
    • Schuller, H.M.1
  • 29
    • 64849103757 scopus 로고    scopus 로고
    • G protein-coupled receptors stimulation and the control of cell migration
    • Cotton M, Claing A. G protein-coupled receptors stimulation and the control of cell migration. Cell Signal 2009; 21: 1045-1053
    • (2009) Cell Signal , vol.21 , pp. 1045-1053
    • Cotton, M.1    Claing, A.2


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