HIF-1α links β-adrenoceptor agonists and pancreatic cancer cells under normoxic condition

Acta Pharmacologica Sinica

Volumn 31, Issue 1, 2010, Pages 102-110

  Hu, Heng Tong ^a   Ma, Qing Yong ^a   Zhang, Dong ^a   Shen, Su Gang ^a   Han, Liang ^a   Ma, Ya Dong ^a   Li, Ruo Fei ^a   Xie, Ke Ping ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

adrenergic receptor; Akt; Epidermal growth factor receptor; ERK1 2; Hypothalamic pituitary adrenal axis; Hypoxia inducible factor 1 ; Pancreatic cancer; Protein kinase A

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHEMOKINE RECEPTOR CXCR4; CYCLIC AMP; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FORSKOLIN; GELATINASE B; GLUCOSE TRANSPORTER 1; ISOPRENALINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; PROTEIN KINASE B; SALBUTAMOL; SMALL INTERFERING RNA; VASCULOTROPIN; XAMOTEROL; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ARTICLE; CANCER CELL CULTURE; CELL HYPOXIA; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PANCREAS CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; COMPARATIVE STUDY; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; PANCREAS TUMOR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 74549184487     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.181     Document Type: Article

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