Phytoestrogen-rich herb formula "xLGB" prevents OVX-induced deterioration of musculoskeletal tissues at the hip in old rats

Journal of Bone and Mineral Metabolism

Volumn 23, Issue SUPPL. 1, 2005, Pages 55-61

  Qin, Ling ^a   Zhang, Ge ^a   Hung, Wing Yin ^a   Shi, Yinyu ^b   Leung, Kwoksui ^a   Yeung, Hiu Yan ^a   Leung, Pingchung ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Biochemical markers; Herbal medicine; Mechanicaltest; Micro CT; Osteoporosis; Phytoestrogen; PQCT; Rats; Uterine

Indexed keywords

BIOLOGICAL MARKER; DAIDZEIN; GENISTEIN; GROWTH INHIBITOR; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; PLANT MEDICINAL PRODUCT;

ANIMAL; ARTICLE; BONE DENSITY; DRUG EFFECT; FEMALE; FEMUR; METABOLISM; OSTEOPOROSIS; OVARIECTOMY; PATHOLOGY; RAT; SKELETAL MUSCLE; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; BONE DENSITY; FEMALE; FEMUR; GENISTEIN; GROWTH INHIBITORS; ISOFLAVONES; MUSCLE, SKELETAL; OSTEOPOROSIS; OVARIECTOMY; PHYTOESTROGENS; PLANT PREPARATIONS; RATS; RATS, WISTAR;

EID: 21444456060     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03026324     Document Type: Article

References (57)

1. Lau EMC (1997) The epidermiology of osteoporosis in Asia. In: Lau EMC (ed) Osteoporosis in Asia. World Scientific, Singapore, pp 1-20
2. BL Riggs LJ Melton 1995 The world-wide problem of osteoporosis: insights afforded by epidemiology Bone 17 505 511
3. HD Nelson LL Humphrey P Nygren SM Teutsch JD Allan 2002 Postmenopausal hormone replacement therapy: scientific review JAMA 288 872 881
4. L Poirier-Solomon 2002 HRT. Findings from the Women's Health Initiative Diabetes Forecast 55 12 34 36
5. MA Dambacher S Schmitt E Schacht M Ito M Neff R, Qin L Müller YL Zhao 2004 Bone structures in vitro and in vivo in animals and in men - a view into the future J Miner Stoffwechs 2 22 28
6. AJ Blake J Morgan MJ Bendali 1998 Falls by elderly persons at home: prevalence and associated factors Age Aging 17 365 372
7. DB Burr 1997 Muscle strength, bone, mass and age-related bone loss J Bone Miner Res 12 1547 1551
8. SR Cummings 1995 Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group N Engl J Med 332 767 773
9. AL Fisher 2004 Of worms and women: sarcopenia and its role in disability and mortality J Am Geriatr Soc 52 1185 1890
10. NIH statement on osteoporosis prevention, diagnosis, and therapy (http://consensus.nih.gov/cons/cons.htm)
11. L Xu A Lu X Zhao 1996 Very low rates of hip fracture in Beijing, People's Republic of China: the Beijing Osteoporosis Project Am J Epidemiol 144 901 907
12. H Adlercreutz 2002 Phyto-oestrogens and cancer Lancet Oncol 3 364 373
13. LL Lien EJ Lien 1996 Hormone therapy and phytoestrogens J Clin Pharm Ther 21 101 111
14. J Mei SSC Yeung AWC Kung 2001 High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but not premenopausal women J Clin Endocrinol Metab 86 5217 5221
15. LA Ramsey BS Ross RG Fischer 1999 Phytoestrogens and the management of menopause Adv Nurse Practitioners 7 26 30
16. SJ An 2000 Effect of kidney-tonifying herbs on ovary function and bone mass in postmenopausal women Chin J Osteoporosis 6 55 59
17. H Li T Miyahara Y Tezuka T Namba N Nemoto S Tonami Tada T Seto H S Kadota 1998 The effect of Kampo formulae on bone resorption in vitro and in vivo I. Active constituents of Tsu- kan-gan. Biol Pharm Bull 21 1322 1326
18. S Hidaka Y Okamoto K Nakajima M Suekawa SY Liu 1997 Preventive effects of traditional Chinese (Kampo) medicines on experimental osteoporosis induced by ovariectomy in rats Calcif Tissue Int 61 239 246
19. S Hidaka Y Okamoto Y Yamada Y Kon T Kimura 1999 Japanese herbal medicine, Chujo-to, has a beneficial effect on osteoporosis in rats Phytother Res 13 14 19
20. S Sakamoto S Sassa H Kudo S Suzuki T Mitamura H Shinoda 2000 Preventive effects of a herbal medicine on bone loss in rats treated with a GnRH agonist Eur J Endocrinol 143 139 142
21. QinL (2002) Research and development of herbal formulae for prevention and treatment of osteoporosis. International Bone Research Instructional Course and Hands-on Workshop, Hong Kong, pp 112-120
22. YY Shi 1998 Comparative study of four Chinese formulas on prevention of osteoporosis Chin J Osteoporosis 4 68 70
23. YY Shi 2000 Summary report on Xianlingubao capsule for treatment of osteoporosis - clinical investigations Int J Chin Orthop 2 18 21
24. Yin J, GuoL (eds) (1993) Modern Study and Clinical Applications on Chinese Materia Medica. Xue Yuan, Beijing, pp 382-652
25. HF Huang JS You 1997 The use of Chinese herbal medicine on experimental fracture healing Am J Chin Med 25 351 356
26. KM Prestwood 2003 Editorial: The search for alternative therapies for menopausal women: estrogenic effects of herbs J Clin Endocrinol Metab 88 4075 4076
27. World Health Organization (1998) Regulatory situation of herbal medicines: a worldwide review. World Health Organization, Geneva
28. WHO Traditional Medicine Strategy 2002-2005. http://www.who. int/medicines/organization/trm/orgtrmmain.shtml
29. JL Tang PC Leung 2001 An efficacy-driven approach to the research and development of traditional Chinese medicine HK Med J 7 375 380
30. G Zhang L Qin YY Shi KS Leung 2004 Comparison between axial compression and lateral fall configurations: a rat proximal femur model J Nippon Soc Bone Morphom 14 97 97
31. G Zhang L Qin WY Hung YY Shi KS Leung 2002 Comparison of pQCT and DXA analysis for establishment of osteoporotic model in proximal femur of mature ovariectomized rats Chin J Orthop 22 432 436
32. WS Siu L Qin WH Cheung KS Leung 2004 A study of trabecular bones in ovariectomized goats with micro-computed tomography and peripheral quantitative computed tomography Bone 35 21 26
33. AC Courtney EF Wachtel ER Myers 1995 Age related reductions in the strength of the femur tested in a fall-loading configuration J Bone Joint Surg 77A 387 395
34. A Colwell RGG Russell R Eastell 1993 Factors affecting the assay of urinary 3-hydroxy pyridinium crosslinks of collagen as markers of bone resorption Eur J Clin Invest 23 341 349
35. P Chomczynski 1993 A reagent for the single-step simultaneous isolation of RNA, DNA, and proteins from cell and tissue samples Biotechnique 15 532 537
36. C Wright H Haddad 1997 Analysis of myosin heavy chain mRNA expression by RT-PCR J Appl Physiol 83 1389 1396
37. TT Andreassen PH Jorgensen A Flyvbjerg H Ørskov H Oxlund 1995 Growth hormone stimulates bone formation and strength of cortical bone in aged rats J Bone Miner Res 10 1057 1067
38. L Mosekilde L Tornvig JS Thomsen PB Orhii MJ Banu DN Kalu 2000 Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia Bone 26 643 651
39. LP Wang PB Orhii J Banu DN Kalu 2001 Bone anabolic effects of separate and combined therapy with growth hormone and parathyroid hormone on femoral neck in aged ovariectomized osteopenic rats Mech Ageing Dev 122 89 104
40. M Casanova L You KW Gaido S Archibeque-Engle DB Janszen HA Heck 1999 Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro Toxicol Sci 51 236 244
41. GGJM Kuiper B Carlsson K Grandien 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β Endocrmology 138 863 870
42. JJ Anderson SC Garner 1998 Phytoestrogens and bone Baillieres Clin Endocrinol Metab 12 543 557
43. Y Onoe C Miyaura H Ohta S Nozzawa T Suda 1997 Expression of estrogen receptor β in rat bone Endocrinology 138 4509 4512
44. HC Blair SE Jordan TG Peterson S Barnes 1996 Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats J Cell Biochem 61 629 637
45. M Xu IM Dick R Day D Randall RL Prince 2003 Effects of a herbal extract on the bone density, strength and markers of bone turnover of mature ovariectomized rats Am J Chin Med 31 87 101
46. S Yu K Chen S Li K Zhang 1999 In vitro and in vivo studies of the effect of a Chinese herb medicine on osteoclastic bone resorption Chin J Dental Res 2 7 11
47. BH Arjmandi RS Birnbaum S Juma E Barengolts SC Kukreja 2000 The synthetic phytoestrogen, ipriflavone, and estrogen prevent bone loss by different mechanisms Calcif Tissue Int 66 61 65
48. G Albrand 2003 Independent predictors of all osteoporosis-related fractures in healthy postmenopausal women: the OFELY Study Bone 32 78 85
49. WSS Jee 2000 Principles in bone physiology J Musculoskel Neuron Interact 1 11 13
50. B Glenmark M Nilsson H Gao 2004 Difference in skeletal muscle function in males vs females; role of estrogen receptor-beta Am J Physiol Endocrinol Metab 287 E1125 E1131
51. B Wiik M Glenmark M Ekman 2003 Oestrogen receptor β is expressed in adult human skeletal muscle both at the mRNA and protein level Acta Physiol Scand 179 381 387
52. RP Huang CT Rubin KJ McLeod 1999 Changes in postural muscle dynamics as a function of age J Gerontol A Biol Sci Med Sci 54 B 352 357
53. American College of Sports Medicine Position Stand (1998) Exercise and physical activity for older adults. Med Sci Sports Exer 30:992-1008
54. Li GP, Qin L, Chan KM (2001) Health benefits of Tai Chi Chuan in older individuals. In: Maffullii N, Chan KM, Macdonald R, Malina RM, Parker T (ed) Sports Medicine for Specific Ages and Abilities. Churchill Livingstone, Edinburgh, pp 315-324
55. LA Lipsitz I Nakajima M Gagnon 1994 Muscle strength and fall rates among residents of Japanese and American nursing homes: an international cross-cultural study J Am Geriatr Soc 42 953 959
56. S Schiaffino C Reggiani 1996 Molecular diversity of myofibrillar proteins: gene regulation and functional significance Physiol Rev 76 371 423
57. L Qin YY Shi 2004 Call for establishment of general guidelines for evaluation of traditional herbal medicine developed for prevention and treatment of osteoporosis Chin J Osteoporosis 10 356 366