3D-QSAR studies of arylcarboxamides with inhibitory activity on InhA using pharmacophore-based alignment

Chemical Biology and Drug Design

Volumn 75, Issue 2, 2010, Pages 195-203

  Lu, Xiao Yun ^a   Chen, Ya Dong ^a   You, Qi Dong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

3D QSAR; Arylcarboxamides; Conformation; InhA; Pharmacophore

Indexed keywords

ARYLCARBOXAMIDE DERIVATIVE; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); ENOYL ACYL CARRIER PROTEIN REDUCTASE INHIBITOR; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG CONFORMATION; DRUG SCREENING; DRUG TARGETING; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

AMIDES; ANTITUBERCULAR AGENTS; COMPUTER SIMULATION; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); INDOLES; LEAST-SQUARES ANALYSIS; MODELS, CHEMICAL; MODELS, MOLECULAR; PIPERAZINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 74549151761     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00926.x     Document Type: Article

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