Application of the Margin of Exposure (MoE) approach to substances in food that are genotoxic and carcinogenic. Example: Benzene, CAS: 71-43-2

Food and Chemical Toxicology

Volumn 48, Issue SUPPL. 1, 2010, Pages

  Smith, Benjamin ^a   Cadby, Peter ^a   DiNovi, Michael ^b   Setzer, R Woodrow ^c  

^a Email:   (Switzerland)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Benzene; Food; Margin of exposure (MoE)

Indexed keywords

BENZENE;

ARTICLE; BREAST CANCER; CANCER RISK; CARCINOGENICITY; CYTOKINESIS; DIETARY INTAKE; DNA DAMAGE; DOSE RESPONSE; EAR CANCER; FOOD CONTAMINATION; GENOTOXICITY; HUMAN; LACRIMAL GLAND DISEASE; LIVER ADENOMA; LIVER CARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; LYMPHOMA; NONHUMAN; OVARY TUMOR; QUALITY CONTROL; RISK ASSESSMENT; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; STOMACH CARCINOMA; TOXICITY TESTING;

ANIMALS; BENZENE; BENZENE DERIVATIVES; CARCINOGENS; DATA INTERPRETATION, STATISTICAL; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD CONTAMINATION; HUMANS; MALE; MICE; MODELS, STATISTICAL; MUTAGENS; NEOPLASMS; RATS;

EID: 74549146991     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.10.015     Document Type: Article

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