Benzene-induced genotoxicity

Journal of Toxicology and Environmental Health - Part A

Volumn 61, Issue 5-6, 2000, Pages 347-351

  Whysner, John ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE; CLASTOGEN; DNA TOPOISOMERASE (ATP HYDROLYSING); HYDROQUINONE;

BIOTRANSFORMATION; CHROMOSOME ABERRATION; CONFERENCE PAPER; DNA ADDUCT; DNA BINDING; DNA DAMAGE; GENOTOXICITY; HUMAN; LEUKEMOGENESIS; METABOLISM; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BENZENE; CARCINOGENS; DNA; DNA ADDUCTS; DNA DAMAGE; HUMANS; LEUKEMIA;

EID: 0033784451     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/00984100050166343     Document Type: Article

References (10)

1. Arfellini, G., Grilli, S., Colacci, A., Mazullo, M., and Prodi, G. 1985. In vivo and in vitro binding of benzene to nucleic acids and proteins of various rat and mouse organs. Cancer Lett. 28:159-168.
2. 1mice treated with benzene: implications for molecular dosimetry. Environ. Health Perspect. Suppl. 104:1189-1193.
3. Corbett, A., and Osheroff, N. 1993. When good enzymes go bad: Conversion of topoisomerase I I to a cellular toxin by antineoplastic drugs. Chem. Res. Toxicol. 6:585-597.
4. 1mice. Carcinogenesis 18:2421-2427.
5. International Agency for Research on Cancer. 1987. Genetic and related effects: An updating of selected I ARC Monographs from volumes 1to 42. Benzene. IARCMonogr. Suppl. 6:91-95.
6. Mazullo, M., Bartoli, S., Colacci, A., Grilli, S., Lattanzi, G., Niero, A., Turina, M. P., and Parodi, S. 1989. Benzene adducts with rat nucleic acids and proteins: Dose-response relationship after treatment in vivo. Environ. Health Perspect. 82:259-266.
7. 32P-postlabeling with the DNA adduct formed in HL-60 cells treated with hydroquinone. Chem. Res. Toxicol. 9:593-598.
8. 32P-labelled dinucleotides and nucleosides monophosphates. In Human carcinogenesis exposure: Biomonitoring and risk assessment, eds. R. C. Garner, P. B. Farmer, G. T. Steel, and A. S. Wright, pp. 369-380. Oxford: IRL Press.
9. Tewey, K. M., Chen, G. L., Nelson, E. M., and Liu, L. F. 1984. Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J. Biol. Chem. 259: 9182-9187.
10. Whysner, J., Verna, L., English, J. C., and Williams, G. M. 1995. Analysis of studies related to tumori-genicity induced by hydroquinone. Regul. Toxicol. Pharmacol. 21:158-176.