Preconditioning with Porphyromonas gingivalis lipopolysaccharide may confer cardioprotection and improve recovery of the electrically induced intracellular calcium transient during ischemia and reperfusion

Journal of Periodontal Research

Volumn 45, Issue 1, 2010, Pages 100-108

  Fan, M H M ^a   Wong, K L ^a   Wu, S ^a   Leung, W K ^a,b   Yam, W C ^a   Wong, T M ^a,c  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cardiac myocyte; Lipopolysaccharide; Myocardial reperfusion injury; Porphyromonas gingivalis

Indexed keywords

CALCIUM; CALCIUM CHANNEL; CARDIOTONIC AGENT; LIPOPOLYSACCHARIDE;

ACTION POTENTIAL; ANIMAL; ARTICLE; CALCIUM SIGNALING; COMPARATIVE STUDY; CONVALESCENCE; CYTOSOL; DRUG EFFECT; HEART CONTRACTION; HEART INFARCTION; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; METHODOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PORPHYROMONAS GINGIVALIS; RANDOMIZATION; RAT; REPERFUSION INJURY; SARCOLEMMA; SARCOPLASMIC RETICULUM; SPRAGUE DAWLEY RAT; TIME;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CARDIOTONIC AGENTS; CYTOSOL; HEART VENTRICLES; INJECTIONS, INTRAPERITONEAL; ISCHEMIC PRECONDITIONING, MYOCARDIAL; LIPOPOLYSACCHARIDES; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PORPHYROMONAS GINGIVALIS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SARCOLEMMA; SARCOPLASMIC RETICULUM; TIME FACTORS;

EID: 74549115179     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2009.01206.x     Document Type: Article

References (47)

1. Stelzel M, Conrads G, Pankuweit S et al. Detection of Porphyromonas gingivalis DNA in aortic tissue by PCR. J Periodontol 2002 73 : 868 870.
2. Bahekar AA, Singh S, Saha S, Molnar J, Arora R. The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis. Am Heart J 2007 154 : 830 837.
3. Geerts SO, Nys M, De Mol P et al. Systemic release of endotoxins induced by gentle mastication: association with periodontitis severity. J Periodontol 2002 73 : 73 78.
4. Lamont RJ, Jenkinson HF. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 1998 62 : 1244 1263.
5. Deshpande RG, Khan MB, Genco CA. Invasion of aortic and heart endothelial cells by Porphyromonas gingivalis. Infect Immun 1998 66 : 5337 5343.
6. Hu SW, Huang CH, Huang HC, Lai YY, Lin YY. Transvascular dissemination of Porphyromonas gingivalis from a sequestered site is dependent upon activation of the kallikrein/kinin pathway. J Periodont Res 2006 41 : 200 207.
7. Haffajee AD, Socransky SS. Microbial etiologic agents of destructive periodontal disease. Periodontology 2000 1994 5 : 78 111.
8. Hajishengallis G, Sharma A, Russell MW, Genco RJ. Interactions of oral pathogens with toll-like receptors: possible role in atherosclerosis. Ann Periodontol 2002 7 : 72 78.
9. Ogawa T, Asai Y, Makimura Y, Tamai R. Chemical structure and immunobiological activity of Porphyromonas gingivalis lipid A. Front Biosci 2007 12 : 3795 3812. Review.
10. Li C, Ha T, Kelley J et al. Modulating toll-like receptor mediated signaling by (1→3)-β-D-glucan rapidly induces cardioprotection. Cardiovasc Res 2004 61 : 538 547.
11. Ha T, Hua F, Liu X et al. Lipopolysaccharide-induced myocardial protection against ischemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res 2008 78 : 546 553.
12. Katz AM. Physiology of the Heart, 4th edition. Philadelphia : Lippincott Williams & Wilkins, 2006 162 202.
13. Yu XC, Li HY, Wang HX, Wong TM. U-50488H inhibits effects of norepinephrine in rat cardiomyocytes: cross-talk between kappa-opioid and beta-adreneric receptors. J Mol Cell Cardiol 1998 30 : 405 413.
14. Westphal O, Luderitz O, Bister F. Uber die extraction von bacterien mit phenol-wasser. Z Naturforsch 1952 78 : 148 155.
15. Ashimoto A, Chen C, Bakker I et al. Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol 1996 11 : 266 273.
16. Aas JA, Barbuto SM, Alpagot T, Olsen I, Dewhirst FE, Paster BJ. Subgingival plaque microbiota in HIV positive patients. J Clin Periodontol 2007 34 : 189 195.
17. Qureshi N, Takayama K, Meyer KC et al. Chemical reduction of 3-oxo and unsaturated groups in fatty acids of diphosphoryl lipid A from the lipopolysaccharide of Rhodopseudomonas sphaeroides. Comparison of biological properties before and after reduction. J Biol Chem 1991 266 : 6532 6538.
18. Al-Qutub MN, Braham PH, Karimi-Naser LM, Liu X, Genco CA, Darveau RP. Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide. Infect Immun 2006 74 : 4474 4485.
19. Brown JM, Grosso MA, Terada LS et al. Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischaemic-reperfusion injury of isolated rat hearts. Proc Natl Acad Sci USA 1989 86 : 2516 2520.
20. Neviere RR, Li FY, Singh T, Myers ML, Sibbald W. Endotoxin induces a dose-dependent myocardial cross-tolerance to ischemia-reperfusion injury. Crit Care Med 2000 28 : 1439 1444.
21. Wang GY, Wu S, Pei JM, Yu XC, Wong TM. Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats. Am J Physiol 2001 280 : H384 H391.
22. Wu S, Li HY, Wong TM. Cardioprotection of preconditioning by metabolic inhibition in rat ventricular myocyte. Involvement of kappa-opioid receptor. Circ Res 1999 84 : 1388 1395.
23. 2+ transient in single ventricular myocytes: A useful parameter for the study of cardiac drugs. Clin Exp Pharm Physiol 1999 26 : 835 836.
24. Rowland RT, Meng X, Cleveland JC Jr., Meldrum DR, Harken AH, Brown JM. LPS-induced delayed myocardial adaptation enhances acute preconditioning to optimize postischemic cardiac function. Am J Physiol 1997 272 : H2708 15.
25. Meng X, Ao L, Brown JM et al. LPS induces late cardiac functional protection against ischemia independent of cardiac and circulating TNF-α. Am J Physiol 1997 273 : H1894 H1902.
26. Cavaillon JM, Adrie C, Fitting C, Adib-Conquy M. Endotoxin tolerance: is there a clinical relevance? J Endotoxin Res 2003 9 : 101 107.
27. Gioannini TL, Weiss JP. Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells. Immunol Res 2007 39 : 249 260. Review.
28. Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor-kappa-B by oxidative stress in cardiac myocytes. J Biol Chem 2001 276 : 5197 5203.
29. Southerland JH, Taylor GW, Moss K, Beck JD, Wallach D. Commonality in chronic inflammatory diseases: periodontitis, diabetes and coronary heart disease. Periodontology 2000 2006 40 : 130 143.
30. Teng YTA. Protective and destructive immunity in the periodontium: Part 1- innate and humoral immunity and the periodontium. J Dent Res 2006 85 : 198 208.
31. Tapping RI, Akashi S, Miyake K, Godowski PJ, Tobias PS. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides. J Immunol 2000 165 : 5780 5787.
32. Abdulla D, Goralski KB, Del Busto Cano EG, Renton KW. The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation. Drug Metab Dispos 2005 33 : 1521 1531.
33. Freudenberg MA, Freudenberg N, Galanos C. Time course of cellular distribution of endotoxin in liver, lungs and kidneys of rats. Br J Exp Pathol 1982 63 : 56 65.
34. van Oosten M, van de Bilt E, van Berkel TJC, Kuiper J. New scavenger receptor-like receptors for the binding of lipopolysaccharide to liver endothelial and Kupffer cells. Infect Immun 1998 66 : 5107 5112.
35. Vreugdenhil ACE, Rousseau CH, Hartung T, Greve JWM, van't Veer C, Buurman WA. Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons. J Immunol 2003 170 : 1399 1405.
36. Pussinen PJ, Tuomisto K, Jousilahti P, Havulinna AS, Sundvall J, Salomaa V. Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events. Arterioscler Thromb Vasc Biol 2007 27 : 1433 1439.
37. Meng X, Brown JM, Ao L et al. Endotoxin induces cardiac HSP70 and resistance to endotoxemic myocardial depression in rats. Am J Physiol 1996 271 : C1316 C1324.
38. Zhou JJ, Pei JM, Wang GY et al. Inducible HSP70 mediates delayed cardioprotection via U-50488H pretreatment in rat ventricular myocytes. Am J Physiol Heart Circ Physiol 2001 281 : H40 H47.
39. Eising GP, Mao L, Schmid-Schonbein GW, Engler RL, Ross J. Effects of induced tolerance to bacterial lipopolysaccharide on myocardial infarct size in rats. Cardiovasc Res 1996 31 : 73 81.
40. Hoshida S, Kuzuya T, Fuji H et al. Sublethal ischaemia alters myocardial antioxidant activity in canine heart. Am J Physiol 1993 264 : H33 H39.
41. Kuzuya T, Hoshida S, Yamashita N et al. Delayed effects of sublethal ischaemia on the acquisition of tolerance to ischaemia. Circ Res 1993 72 : 1293 1299.
42. Marber MS, Latchman DS, Walker JM, Yellon DM. Cardiac stress protein elevation 24 hours after brief ischaemic or heat stress is associated with resistance to myocardial infarction. Circulation 1993 88 : 1264 1272.
43. Zingatelli B, Halushka PV, Caputi AP, Cook JA. Increased nitric oxide synthase during the development of endotoxin tolerance. Shock 1995 3 : 102 108.
44. Carayol N, Chen J, Yang F et al. A dominant function of IKK/NF-kB signaling in global lipopolysaccharide-induced gene expression. J Biol Chem 2006 281 : 31142 31151.
45. Herbertson M, Werner H, Goddard C et al. Anti-tumor necrosis factor-alpha prevents decreases ventricular contractility in endotoxemic pigs. Am J Respir Crit Care Med 1995 152 : 480 488.
46. Haudek SB, Spencer E, Bryant DD et al. Overexpression of cardiac I-kBa prevents endotoxin-induced myocardial dysfunation. Am J Physiol Heart Circ Physiol 2001 280 : H962 H968.
47. Nemoto S, Vellejo JG, Kneufermann P et al. Escherichia coli LPS-induced LV dysfunction role of toll-like receptor-4 in the adult heart. Am J Physiol Heart Circ Physiol 2002 282 : H2316 H2323.