Construction of single-chain Fv with two possible CDR3H conformations but similar inter-molecular forces that neutralize bovine herpesvirus 1

Molecular Immunology

Volumn 47, Issue 5, 2010, Pages 953-960

  Koti, Madhuri ^a   Farrugia, William ^b   Nagy, Eva ^a   Ramsland, Paul A ^b   Kaushik, Azad K ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b BURNET INSTITUTE   (Australia)

Author keywords

Antibody; Antibody modeling; BoHV 1; Fv; scFv

Indexed keywords

CDR3H POLYPEPTIDE; CYSTEINE; EPITOPE; IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY; POLYPEPTIDE; RECOMBINANT SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN DETECTION; ARTICLE; BINDING SITE; BOVINE HERPES VIRUS; CONTROLLED STUDY; DISULFIDE BOND; ELECTRIC POTENTIAL; GENE CONSTRUCT; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IN VITRO STUDY; MOLECULAR MODEL; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; BINDING SITES, ANTIBODY; CATTLE; CELL LINE; COMPLEMENTARITY DETERMINING REGIONS; HERPESVIRUS 1, BOVINE; IMMUNOGLOBULIN G; INFECTIOUS BOVINE RHINOTRACHEITIS; MICE; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS;

BOS; BOVINAE; BOVINE HERPESVIRUS 1; PICHIA PASTORIS;

EID: 74449089167     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.11.011     Document Type: Article

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