Giα3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event

American Journal of Physiology - Renal Physiology

Volumn 287, Issue 5 56-5, 2004, Pages

  Pedrosa, Rui ^a   Gomes, Pedro ^a   Hopfer, Ulrich ^b   Jose, Pedro A ^c   Soares Da Silva, Patrício ^a  

^a Institute of Pharmacology and Therapeutics   (Portugal)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypertension; Na+ H+ exchange; Protein kinases

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTIBODY; CALCIMYCIN; CHELERYTHRINE; CHOLERA TOXIN; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; ENZYME; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PERTUSSIS TOXIN; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PROTEIN INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SODIUM PROTON EXCHANGE PROTEIN 3; SULPIRIDE; UNCLASSIFIED DRUG; 7 HYDROXY 2 N,N DIPROPYLAMINOTETRALIN; 7-HYDROXY-2-N,N-DIPROPYLAMINOTETRALIN; CALCIUM; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DRD3 PROTEIN, RAT; FLAVONOID; GNAI3 PROTEIN, RAT; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3; TETRALIN DERIVATIVE;

ADOLESCENT; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL IMMORTALIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; HYPERTENSION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; RAT; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; CELL LINE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; CALCIUM; CELL LINE; CHOLERA TOXIN; DOPAMINE ANTAGONISTS; DOWN-REGULATION; FLAVONOIDS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); IMIDAZOLES; KIDNEY TUBULES, PROXIMAL; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PROTEIN KINASE C; PYRIDINES; RATS; RATS, INBRED SHR; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; RECEPTORS, G-PROTEIN-COUPLED; SODIUM-HYDROGEN ANTIPORTER; SULPIRIDE; TETRAHYDRONAPHTHALENES;

EID: 7444248038     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00139.2004     Document Type: Article

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