Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: A reassignment of the active-site binding mode

Acta Crystallographica Section D: Biological Crystallography

Volumn 60, Issue 3, 2004, Pages 453-462

  Retailleau, Pascal ^a   Colloc'h, Nathalie ^b   Vivarès, Denis ^c,h   Bonneté, Françoise ^c   Castro, Bertrand ^d   El Hajji, Mohamed ^d   Mornon, Jean Paul ^e   Monard, Gérald ^f   Prangé, Thierry ^a,g  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIVERSITÉ DE CAEN   (France)

^c AIX MARSEILLE UNIVERSITÉ   (France)

^d SANOFI   (France)

^e UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^f NANCY UNIVERSITÉ   (France)

^g UNIVERSITÉ PARIS DESCARTES   (France)

^h University of Delaware   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPERGILLUS FLAVUS;

8 AZAXANTHINE; 8-AZAXANTHINE; BACTERIAL PROTEIN; DRUG DERIVATIVE; ENZYME INHIBITOR; FUNGAL PROTEIN; OXONIC ACID; URATE OXIDASE; URIC ACID; XANTHINE DERIVATIVE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; ASPERGILLUS FLAVUS; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYMOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ASPERGILLUS FLAVUS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FUNGAL PROTEINS; HUMANS; MICE; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; OXONIC ACID; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; URATE OXIDASE; URIC ACID; XANTHINES;

EID: 7444239015     PISSN: 09074449     EISSN: None     Source Type: Journal    
DOI: 10.1107/S0907444903029718     Document Type: Article

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