Effects of angiotensin II on vascular endothelial cells: Formation of receptor-mediated reactive nitrogen species

Biochemical Pharmacology

Volumn 65, Issue 7, 2003, Pages 1189-1197

  Mihm, Michael J ^a,b   Wattanapitayakul, Suvara K ^b   Piao, Sheng Fu ^a   Hoyt, Dale G ^b   Bauer, John Anthony ^a,b,c  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

3 Nitrotyrosine; Angiotensin II; Endothelium; Nitric oxide; Peroxynitrite; Reactive nitrogen species

Indexed keywords

ACETYLCYSTEINE; AMINO ACID; AMINOGUANIDINE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; BIOLOGICAL MARKER; DIPHENYLIODONIUM SALT; LIPOXYGENASE INHIBITOR; LOSARTAN; OXIPURINOL; PEROXYNITRITE; PROTEIN; PROTEIN 3NT; REACTIVE NITROGEN SPECIES; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CAPILLARY ELECTROPHORESIS; CELL LYSATE; CELL STIMULATION; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; IMMUNOBLOTTING; IN VITRO STUDY; LC 50; MALE; MOUSE; NITRATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN MODIFICATION; REGULATORY MECHANISM; SERUM; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

EID: 0345268767     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00012-1     Document Type: Article

References (40)

1. Stroth U., Unger T. The renin-angiotensin system and its receptors. J. Cardiovasc. Pharmacol. 33(Suppl 1):1999;S21-S28.
2. Lonn E.M., Yusuf S., Jha P., Montague T.J., Teo K.K., Benedict C.R., Pitt B. Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection. Circulation. 90:1994;2056-2069.
3. Haber E. The role of renin in normal and pathological cardiovascular homeostasis. Circulation. 54:1976;849-854.
4. Griffin S.A., Brown W.C., MacPherson F., McGrath J.C., Wilson V.G., Korsgaard N., Mulvany M.J., Lever A.F. Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Hypertension. 17:1991;626-635.
5. Ratajska A., Campbell S.E., Cleutjens J.P., Weber K.T. Angiotensin II and structural remodeling of coronary vessels in rats. J. Lab. Clin. Med. 124:1994;408-415.
6. Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K., Harrison D.G. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J. Clin. Invest. 97:1996;1916-1923.
7. Pueyo M.E., Arnal J.F., Rami J., Michel J.B. Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells. Am. J. Physiol. 274:1999;C214-C220.
8. Munzel T., Hink U., Heitzer T., Meinertz T. Role for NADPH/NADH oxidase in the modulation of vascular tone. Ann. NY Acad. Sci. 874:1999;386-400.
9. Spieker L.E., Noll G., Ruschitzka F.T., Maier W., Luscher T.F. Working under pressure: the vascular endothelium in arterial hypertension. J. Hum. Hypertens. 14:2000;617-630.
10. Heitsch H., Brovkovych S., Malinski T., Wiemer G. Angiotensin-(1-7)-stimulated nitric oxide and superoxide release from endothelial cells. Hypertension. 37:2001;72-76.
11. Mancini G.B.J., Henry G.C., Macaya C., O'Neill B.J., Pucillo A.L., Carere R.G., Wargovich T.J., Mudra H., Luscher T.F., Klibaner M.I., Haber H.E., Uprichard A.C.G., Pepine C.J., Pitt B. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease: the TREND (Trial on Reversing Endothelial Dysfunction) study. Circulation. 94:1996;258-265.
12. Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 299:1980;373-376.
13. Barton M. Biology of the endothelium. Clin Cardiol 1997;20:II-3-II-10.
14. Mombouli J.V., Vanhoutte P.M. Endothelial dysfunction: from physiology to therapy. J. Mol. Cell Cardiol. 31:1991;61-74.
15. Vallance P., Moncada S. Nitric oxide - from mediator to medicines. J. R. Coll Physicians Lond. 28:1994;209-219.
16. Freeman B. Free radical chemistry of nitric oxide. Looking at the dark side. Chest. 105(Suppl 3):1994;79S-84S.
17. Blough N.V., Zafiriou O.C. Reaction of superoxide with nitric oxide to form peroxynitrite in alkaline aqueous solution. Inorg. Chem. 24:1985;3504-3505.
18. Beckman J.S., Koppenol W. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am. J. Physiol. 271:1996;C1424-C1437.
19. Beckman J.S. Oxidative damage and tyrosine nitration from peroxynitrite. Chem. Res. Toxicol. 9:1996;836-844.
20. Mihm M.J., Coyle C., Schanbacher B.L., Weinstein D.W., Bauer J.A. Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure. Cardiovasc. Res. 49:2001;798-807.
21. Kooy N.W., Lewis S.J., Royall J.A., Ye Y.Z., Kelly D.R., Beckman J.S. Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite. Crit. Care Med. 25:1997;812-819.
22. Fukuyama N., Takebayashi Y., Hida M., Ishida H., Ichimori K. Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock. Free Radic. Biol. Med. 22:1997;771-774.
23. Wattanapitayakul S.K., Weinstein D.M., Holycross B.J., Bauer J.A. Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders. FASEB J. 14:2000;271-278.
24. Kamisaki Y., Wada K., Bian K., Balabanli B., Davis K., Martin E., Behbod F., Lee Y.C., Murad F. An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc. Natl. Acad. Sci. U.S.A. 95:1998;11584-11589.
25. Souza J.M., Choi I., Chen Q., Weisse M., Daikhin E., Yudkoff M., Obin M., Ara J., Horwitz J., Ischiropoulos H. Proteolytic degradation of tyrosine nitrated proteins. Arch. Biochem. Biophys. 380:2000;360-366.
26. Mihm M.J., Jing L., Bauer J.A. Nitrotyrosine causes selective vascular endothelial dysfunction and DNA damage. J. Cardiovasc. Res. 36:2000;182-187.
27. Gerritsen M.E., Shen C.-P., McHugh M.C., Atkinson W.J., Kiely J.-M., Milstone D.S., Luscinskas F.W., Gimbrone M.A.J. Activation-dependent isolation and culture of murine pulmonary microvascular endothelium. Microcirculation. 2:1995;151-163.
28. Flick D.A., Gifford G.E. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor. J. Immunol. Methods. 68:1984;167-175.
29. Lum H., Roebuck K.A. Oxidant stress and endothelial cell dysfunction. Am. J. Physiol. 280:2001;C719-C741.
30. Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87:2000;840-844.
31. Ischiropoulos H. Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch. Biochem. Biophys. 356:1998;1-11.
32. Li J.M., Mullen A.M., Shah A.M. Phenotypic properties and characteristics of superoxide production by mouse coronary microvascular endothelial cells. J. Mol. Cell Cardiol. 33:2001;1119-1131.
33. phox mRNA expression and NADPH oxidase superoxide generation in rabbit aortic adventitial fibroblasts. Hypertension. 32:1998;331-337.
34. Jaimes E.A., Galceran J.M., Raij L. Angiotensin II induces superoxide anion production by mesangial cells. Kidney Int. 54:1998;775-784.
35. Greenacre S.A.B., Evans P., Halliwell B., Brain S.D. Formation and loss of nitrated proteins in peroxynitrite-treated rat skin in vivo. Biochem. Biophys. Res. Commun. 262:1999;781-786.
36. Tabrizi-Fard M.A., Maurer T.S., Fung H.-L. In vivo disposition of 3-nitro-L-tyrosine in rats: implications on tracking systemic peroxynitrite exposure. Drug Metab. Dispos. 27:1999;429-431.
37. Eiserich J.P., Est'Evez A.G., Bamberg T.V., Ye Y.Z., Chumley P.H., Beckman J.S., Freeman B.A. Microtubule dysfunction by post-translational nitrotyrosination of α-tubulin: a nitric oxide-dependent mechanism of cellular injury. Proc. Natl. Acad. Sci. U.S.A. 96:1999;6365-6370.
38. Kalisz H.M., Erck C., Plessmann U., Wehland J. Incorporation of nitrotyrosine into α-tubulin by recombinant mammalian tubulin-tyrosine ligase. Biochim. Biophys. Acta. 1481:2000;131-138.
39. Krainev A.G., Williams T.D., Bigelow D.J. Enzymatic reduction of 3-nitrotyrosine generates superoxide. Chem. Res. Toxicol. 11:1998;495-502.
40. Kooy N.W., Lewis S.J. Nitrotyrosine attenuates the hemodynamic effects of adrenoceptor agonists in vivo: relevance to the pathophysiology of peroxynitrite. Eur. J. Pharmacol. 310:1996;155-161.