-
1
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF. Met, metastasis, motility and more. Nat Rev Mol Cell Biol 2003;4:915-25.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
2
-
-
0025738047
-
Hepatocyte growth factor-scatter factor: Mitogen, motogen, and met
-
Cold Spring Harbor
-
Gherardi E, Stoker M. Hepatocyte growth factor-scatter factor: mitogen, motogen, and met. Cancer Cells (Cold Spring Harbor) 1991;3:227-32.
-
(1991)
Cancer Cells
, vol.3
, pp. 227-232
-
-
Gherardi, E.1
Stoker, M.2
-
3
-
-
0032189977
-
Developmental roles of Hepatocyte growth factor/scatter factor and its receptor, the c-Met tyrosine kinase
-
Birchmeier C, Gherardi E. Developmental roles of Hepatocyte growth factor/scatter factor and its receptor, the c-Met tyrosine kinase. Trends Cell Biol 1998;8:404-10.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 404-410
-
-
Birchmeier, C.1
Gherardi, E.2
-
4
-
-
0034693753
-
Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
-
Furge KA, Zhang YW, Vande Woude GF. Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene 2000;19:5582-9.
-
(2000)
Oncogene
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
5
-
-
0034015241
-
Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and Hepatocyte growth factor/scatter factor protein in primary gastric carcinomas
-
Park WS, Oh RR, Kim YS, et al. Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and Hepatocyte growth factor/scatter factor protein in primary gastric carcinomas. APMIS 2000;108:195-200.
-
(2000)
APMIS
, vol.108
, pp. 195-200
-
-
Park, W.S.1
Oh, R.R.2
Kim, Y.S.3
-
6
-
-
0035159240
-
MET receptor is overexpressed but not mutated in oral squamous cell carcinomas
-
Morello S, Olivero M, Aimetti M, et al. MET receptor is overexpressed but not mutated in oral squamous cell carcinomas. J Cell Physiol 2001;189:285-90.
-
(2001)
J Cell Physiol
, vol.189
, pp. 285-290
-
-
Morello, S.1
Olivero, M.2
Aimetti, M.3
-
7
-
-
0029759716
-
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor
-
Wang R, Kobayashi R, Bishop JM. Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. Proc Natl Acad Sci USA 1996;93:8425-30.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8425-8430
-
-
Wang, R.1
Kobayashi, R.2
Bishop, J.M.3
-
8
-
-
0028351702
-
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
-
Ponzetto C, Bardelli A, Zhen Z, et al. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 1994;77:261-71.
-
(1994)
Cell
, vol.77
, pp. 261-271
-
-
Ponzetto, C.1
Bardelli, A.2
Zhen, Z.3
-
9
-
-
0037050212
-
Requirement of Stat3 signaling for Hepatocyte growth factor/scatter factor-Met mediated tumorigenesis
-
Zhang YW, Wang LM, Jove R, Vande Woude GF. Requirement of Stat3 signaling for Hepatocyte growth factor/scatter factor-Met mediated tumorigenesis. Oncogene 2002;21:217-26.
-
(2002)
Oncogene
, vol.21
, pp. 217-226
-
-
Zhang, Y.W.1
Wang, L.M.2
Jove, R.3
Vande Woude, G.F.4
-
10
-
-
0035793091
-
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
-
Xiao GH, Jeffers M, Bellacosa A, et al. Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways. Proc Natl Acad Sci USA 2001;98:247-52.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 247-252
-
-
Xiao, G.H.1
Jeffers, M.2
Bellacosa, A.3
-
11
-
-
0034954160
-
The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair
-
Fan S, Ma YX, Gao M, et al. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair. Mol Cell Biol 2001;21:4968-84.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4968-4984
-
-
Fan, S.1
Ma, Y.X.2
Gao, M.3
-
12
-
-
0033754009
-
Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases
-
Harvey P, Clark IM, Jaurand MC, Warn RM, Edwards DR. Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases. Br J Cancer 2000;83:1147-53.
-
(2000)
Br J Cancer
, vol.83
, pp. 1147-1153
-
-
Harvey, P.1
Clark, I.M.2
Jaurand, M.C.3
Warn, R.M.4
Edwards, D.R.5
-
13
-
-
0034934354
-
Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement
-
Lond
-
Kermorgant S, Aparicio T, Dessirier V, Lewin MJ, Lehy T. Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement. Carcinogenesis (Lond) 2001;22:1035-42.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1035-1042
-
-
Kermorgant, S.1
Aparicio, T.2
Dessirier, V.3
Lewin, M.J.4
Lehy, T.5
-
15
-
-
0037453059
-
Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1
-
Tomita N, Morishita R, Taniyama Y, et al. Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1. Circulation 2003;107:1411-7.
-
(2003)
Circulation
, vol.107
, pp. 1411-1417
-
-
Tomita, N.1
Morishita, R.2
Taniyama, Y.3
-
16
-
-
0242331653
-
Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation
-
Zhang YW, Su Y, Volpert OV, Vande Woude GF. Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation. Proc Natl Acad Sci USA 2003;100:12718-23.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12718-12723
-
-
Zhang, Y.W.1
Su, Y.2
Volpert, O.V.3
Vande Woude, G.F.4
-
17
-
-
0035912757
-
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (Hepatocyte growth factor/scatter factor) display antitumor activity in animal models
-
Cao B, Su Y, Oskarsson M, et al. Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (Hepatocyte growth factor/scatter factor) display antitumor activity in animal models. Proc Natl Acad Sci USA 2001;98:7443-8.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7443-7448
-
-
Cao, B.1
Su, Y.2
Oskarsson, M.3
-
18
-
-
0033877297
-
Met/HGF receptor modulates bcl-w expression and inhibits apoptosis in human colorectal cancers
-
Kitamura S, Kondo S, Shinomura Y, et al. Met/HGF receptor modulates bcl-w expression and inhibits apoptosis in human colorectal cancers. Br J Cancer 2000;83:668-73.
-
(2000)
Br J Cancer
, vol.83
, pp. 668-673
-
-
Kitamura, S.1
Kondo, S.2
Shinomura, Y.3
-
19
-
-
0034636444
-
Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells
-
Firon M, Shaharabany M, Altstock RT, et al. Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells. Oncogene 2000;19:2386-97.
-
(2000)
Oncogene
, vol.19
, pp. 2386-2397
-
-
Firon, M.1
Shaharabany, M.2
Altstock, R.T.3
-
20
-
-
0035845485
-
Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase
-
Furge KA, Kiewlich D, Le P, et al. Suppression of Ras-mediated tumorigenicity and metastasis through inhibition of the Met receptor tyrosine kinase. Proc Natl Acad Sci USA 2001;98:10722-7.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10722-10727
-
-
Furge, K.A.1
Kiewlich, D.2
Le, P.3
-
21
-
-
0033568455
-
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression
-
Bethesda
-
Abounader R, Ranganathan S, Lal B, et al. Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression. J Natl Cancer Inst (Bethesda) 1999;91:1548-56.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1548-1556
-
-
Abounader, R.1
Ranganathan, S.2
Lal, B.3
-
22
-
-
0036365052
-
In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
-
Abounader R, Lal B, Luddy C, et al. In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. FASEB J 2002;16:108-10.
-
(2002)
FASEB J
, vol.16
, pp. 108-110
-
-
Abounader, R.1
Lal, B.2
Luddy, C.3
-
23
-
-
10744228765
-
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo
-
Christensen JG, Schreck R, Burrows J, et al. A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Cancer Res 2003;63:7345-55.
-
(2003)
Cancer Res
, vol.63
, pp. 7345-7355
-
-
Christensen, J.G.1
Schreck, R.2
Burrows, J.3
-
24
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (Lond) 2001;411:494-8.
-
(2001)
Nature (Lond)
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
25
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (Lond) 1998;391:806-11.
-
(1998)
Nature (Lond)
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
26
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 1999;13:3191-7.
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
27
-
-
0035502570
-
D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections
-
Lin SL, Sukasweang S, Chuong CM, Rasheed S, Ying SY. D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections. Curr Cancer Drug Targets 2001;1:241-7.
-
(2001)
Curr Cancer Drug Targets
, vol.1
, pp. 241-247
-
-
Lin, S.L.1
Sukasweang, S.2
Chuong, C.M.3
Rasheed, S.4
Ying, S.Y.5
-
28
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G, Soohoo C, Affar el B, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002;99:5515-20.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affar El, B.3
-
30
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002;20:500-5.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
-
31
-
-
0037069417
-
Retroviral delivery of small interfering RNA into primary cells
-
Barton GM, Medzhitov R. Retroviral delivery of small interfering RNA into primary cells. Proc Natl Acad Sci USA 2002;99:14943-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14943-14945
-
-
Barton, G.M.1
Medzhitov, R.2
-
32
-
-
0036653097
-
RNA interference: The new somatic cell genetics?
-
Paddison PJ, Hannon GJ. RNA interference: the new somatic cell genetics? Cancer Cell 2002;2:17-23.
-
(2002)
Cancer Cell
, vol.2
, pp. 17-23
-
-
Paddison, P.J.1
Hannon, G.J.2
-
33
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson DA, Dillon CP, Kwiatkowski AV, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003;33:401-6.
-
(2003)
Nat Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
-
34
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia G, Singer O, Ikawa M, Verma IM. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA 2003;100:1844-8.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
36
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002;99:6047-52.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
37
-
-
0026655776
-
Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
-
Rong S, Bodescot M, Blair D, et al. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol 1992;12:5152-8.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5152-5158
-
-
Rong, S.1
Bodescot, M.2
Blair, D.3
-
38
-
-
0025788025
-
The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase
-
Graziani A, Gramaglia D, Cantley LC, Comoglio PM. The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase. J Biol Chem 1991;266:22087-90.
-
(1991)
J Biol Chem
, vol.266
, pp. 22087-22090
-
-
Graziani, A.1
Gramaglia, D.2
Cantley, L.C.3
Comoglio, P.M.4
-
39
-
-
0038380439
-
Role of the MET/HGF receptor in proliferation and invasive behavior of osteosarcoma
-
Coltella N, Manara MC, Cerisano V, et al. Role of the MET/HGF receptor in proliferation and invasive behavior of osteosarcoma. FASEB J 2003;17:1162-4.
-
(2003)
FASEB J
, vol.17
, pp. 1162-1164
-
-
Coltella, N.1
Manara, M.C.2
Cerisano, V.3
-
40
-
-
0037663944
-
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages
-
Song E, Lee SK, Dykxhoorn DM, et al. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol 2003;77:7174-81.
-
(2003)
J Virol
, vol.77
, pp. 7174-7181
-
-
Song, E.1
Lee, S.K.2
Dykxhoorn, D.M.3
-
41
-
-
0034663422
-
Cell receptors involved in adenovirus entry
-
Nemerow GR. Cell receptors involved in adenovirus entry. Virology 2000;274:1-4.
-
(2000)
Virology
, vol.274
, pp. 1-4
-
-
Nemerow, G.R.1
-
42
-
-
0000421475
-
Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines
-
Pearson AS, Koch PE, Atkinson N, et al. Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines. Clin Cancer Res 1999;5:4208-13.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4208-4213
-
-
Pearson, A.S.1
Koch, P.E.2
Atkinson, N.3
-
43
-
-
0034880138
-
Normal and malignant prostate epithelial cells differ in their response to hepatocyte growth factor/scatter factor
-
Gmyrek GA, Walburg M, Webb CP, et al. Normal and malignant prostate epithelial cells differ in their response to hepatocyte growth factor/scatter factor. Am J Pathol 2001;159:579-90.
-
(2001)
Am J Pathol
, vol.159
, pp. 579-590
-
-
Gmyrek, G.A.1
Walburg, M.2
Webb, C.P.3
-
44
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh CG, Factor VM, Sanchez A, et al. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci USA 2004;101:4477-82.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4477-4482
-
-
Huh, C.G.1
Factor, V.M.2
Sanchez, A.3
-
45
-
-
0033882022
-
Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways
-
Bowers DC, Fan S, Walter KA, et al. Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways. Cancer Res 2000;60:4277-83.
-
(2000)
Cancer Res
, vol.60
, pp. 4277-4283
-
-
Bowers, D.C.1
Fan, S.2
Walter, K.A.3
-
46
-
-
0347093421
-
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3′-OH kinase-Akt pathway
-
Takeuchi K, Ito F. Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3′-OH kinase-Akt pathway. J Biol Chem 2004;279:892-900.
-
(2004)
J Biol Chem
, vol.279
, pp. 892-900
-
-
Takeuchi, K.1
Ito, F.2
-
47
-
-
0038724909
-
c-Met: Structure, functions and potential for therapeutic inhibition
-
Ma PC, Maulik G, Christensen J, Salgia R. c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev 2003;22:309-25.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 309-325
-
-
Ma, P.C.1
Maulik, G.2
Christensen, J.3
Salgia, R.4
-
48
-
-
0242694513
-
Suppression of met expression: A possible cancer treatment
-
Commentary re: S. J. Kim et al., reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. Clin. Cancer Res. 14: 5161-70, 2003
-
Shinomiya N, Vande Woude GF. Suppression of met expression: a possible cancer treatment. Commentary re: S. J. Kim et al., reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model. Clin. Cancer Res. 14: 5161-70, 2003. Clin Cancer Res 2003;9:5085-90.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5085-5090
-
-
Shinomiya, N.1
Vande Woude, G.F.2
-
49
-
-
0036171069
-
Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy
-
Maemondo M, Narumi K, Saijo Y, et al. Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy. Mol Ther 2002;5:177-85.
-
(2002)
Mol Ther
, vol.5
, pp. 177-185
-
-
Maemondo, M.1
Narumi, K.2
Saijo, Y.3
-
50
-
-
0037905558
-
Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells
-
Herynk MH, Stoeltzing O, Reinmuth N, et al. Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells. Cancer Res 2003;63:2990-6.
-
(2003)
Cancer Res
, vol.63
, pp. 2990-2996
-
-
Herynk, M.H.1
Stoeltzing, O.2
Reinmuth, N.3
|