Oligosaccharide sequences in Quillaja saponins by electrospray ionization ion trap multiple-stage mass spectrometry

Journal of Mass Spectrometry

Volumn 39, Issue 6, 2004, Pages 691-701

  Broberg, Susanna ^a   Nord, Lars I ^a   Kenne, Lennart ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Electrospray ionization ion trap multiple stage mass spectrometry; Fragmentation; Oligosaccharide sequencing; Quillaja saponins; Structure determination

Indexed keywords

CARBOHYDRATES; IONIZATION; NEGATIVE IONS; POSITIVE IONS;

ELECTROSPRAY IONIZATION (ESI); OLIGOSACCHARIDE SEQUENCES;

MASS SPECTROMETRY;

ION; MONOSACCHARIDE; OLIGOSACCHARIDE; SAPONIN;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ION TRAP MASS SPECTROMETRY; NEGATIVE ION ELECTROSPRAY; POSITIVE ION ELECTROSPRAY; PRIORITY JOURNAL; QUILLAJA; SPECTRAL SENSITIVITY;

MOLECULAR STRUCTURE; OLIGOSACCHARIDES; PLANT BARK; QUILLAJA; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TREES;

QUILLAJA; QUILLAJA SAPONARIA; SAPONARIA;

EID: 3042817854     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.642     Document Type: Article

References (26)

1. Kensil CR. Saponins as vaccine adjuvants. Crit. Rev. Ther. Drug Carrier Syst. 1996; 13: 1.
2. San Martín R, Briones R. Industrial uses and sustainable supply of Quillaja saponaria (Rosaceae) saponins. Econ. Bot. 1999; 53: 302.
3. Bomford R, Stapleton M, Winsor S, Beesley JE, Jessup EA, Price KR, Fenwick GR. Adjuvanticity and ISCOM formation by structurally diverse saponins. Vaccine 1992; 10: 572.
4. Barr IG, Sjölander A, Cox JC. ISCOMs and other saponin based adjuvants. Adv. Drug Deliv. Rev. 1998; 32: 247.
5. Kersten GFA, Crommelin DJA. Liposomes and ISCOMs. Vaccine 2003; 21: 915.
6. Kensil CR, Patel U, Lennick M, Marciani D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immunol. 1991; 146: 431.
7. Higuchi R, Tokimitsu Y, Fujioka T, Komori T, Kawasaki T, Oakenful DG. Structure of desacylsaponins obtained from the bark of Quillaja saponaria. Phytochemistry 1987; 26: 229.
8. Higuchi R, Tokimitsu Y, Komori T. An acylated triterpenoid saponin from Quillaja saponaria. Phytochemistry 1988; 27: 1165.
9. 13C NMR spectroscopy. Carbohydr. Res. 1996; 280: 1.
10. Guo SJ, Kenne L, Lundgren LN, Rönnberg B, Sundquist BG. Triterpenoid saponins from Quillaja saponaria. Phytochemistry 1998; 48: 175.
11. Guo SJ, Falk E, Kenne L, Rönnberg B, Sundquist BG. Triterpenoid saponins containing an acetylated branched D-fucosyl residue from Quillaja saponaria Molina. Phytochemistry 2000; 53: 861.
12. Guo SJ, Kenne L. Characterization of some O-acetylated saponins from Quillaja saponaria Molina. Phytochemistry 2000; 54: 615.
13. Guo SJ, Kenne L. Structural studies of triterpenoid saponins with new acyl components from Quillaja saponaria Molina. Phytochemistry 2000; 55: 419.
14. Nord LI, Kenne L. Separation and structural analysis of saponins in a bark extract from Quillaja saponaria Molina. Carbohydr. Res. 1999; 320: 70.
15. Nord LI, Kenne L. Novel acetylated triterpenoid saponins in a chromatographic fraction from Quillaja saponaria Molina. Carbohydr. Res. 2000; 329: 817.
16. Nyberg NT, Kenne L, Rönnberg B, Sundquist BG. Separation and structural analysis of some saponins from Quillaja saponaria Molina. Carbohydr. Res. 2000; 323: 87.
17. Nyberg NT, Baumann H, Kenne L. Solid-phase extraction NMR studies of chromatographic fractions of saponins from Quillaja saponaria. Anal. Chem. 2003; 75: 268.
18. van Setten DC, van de Werken G, Zomer G, Kersten GFA. Glycosyl compositions and structural characteristics of the potential immuno-adjuvant active saponins in the Quillaja saponaria Molina extract quil A. Rapid Commun. Mass Spectrom. 1995; 9: 660.
19. 1H NMR spectra for saponins from Quillaja saponaria Molina. Anal. Chim. Acta 2001; 446: 199.
20. Liu YZ, Liang F, Cui LJ, Xia M, Zhao LY, Yang YC, Shi JG, Abliz Z. Multi-stage mass spectrometry of furostanol saponins combined with electrospray ionization in positive and negative ion modes. Rapid Commun. Mass Spectrom. 2004; 18: 235.
21. Cui M, Song FR, Zhou Y, Liu ZQ, Liu SY. Rapid identification of saponins in plant extracts by electrospray ionization multi-stage tandem mass spectrometry and liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2000; 14: 1280.
22. Huhman DV, Sumner LW. Metabolic profiling of saponins in Medicago sativa and Medicago truncatula using HPLC coupled to an electrospray ion-trap mass spectrometer. Phytochemistry 2002; 59: 347.
23. n). Anal. Sci. 2002; 18: 481.
24. van Setten DC, ten Hove GJ, Wiertz EJHJ, Kamerling JP, van de Werken G. Multiple-stage tandem mass spectrometry for structural characterization of saponins. Anal. Chem. 1998; 70: 4401.
25. van Setten DC, Zomer G, van de Werken G, Wiertz EJHJ, Leeflang BR, Kamerling JP. Ion trap multiple-stage tandem mass spectrometry as a pre-NMR tool in the structure elucidation of saponins. Phytochem. Anal. 2000; 11: 190.
26. Domon B, Costello CE. A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates. Glycoconj J. 1988; 5: 397.