A potential role for islet-1 in post-natal angiogenesis and vasculogenesis

Thrombosis and Haemostasis

Volumn 103, Issue 1, 2010, Pages 188-197

  Barzelay, Aya ^a,b   Ben Shoshan, Jeremy ^a,b   Entin Meer, Michal ^a   Maysel Auslender, Sofia ^a   Afek, Arnon ^b,c   Barshack, Iris ^b,c   Keren, Gad ^a,b   George, Jacob ^a,b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

Angiogenesis; Bone marrow stromal cells; Cell therapy; Gene therapy; Isl1

Indexed keywords

FIBRONECTIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LIM HOMEODOMAIN TRANSCRIPTION FACTOR ISLET 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CELL ADHESION; CELL CYCLE; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CYTOKINE RELEASE; ENDOTHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; VASCULARIZATION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ANIMALS; CELL ADHESION; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; ENDOTHELIAL CELLS; FIBRONECTINS; GENETIC VECTORS; HOMEODOMAIN PROTEINS; INTERLEUKIN-1BETA; MALE; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; RATS; RATS, WISTAR; RETROVIRIDAE; TIME FACTORS; TRANSDUCTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 74249116579     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH09-07-0433     Document Type: Article

References (35)

1. Kelly RG, Brown NA, Buckingham ME. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev Cell 2001; 1: 435-440.
2. Cai CL, Liang X, Shi Y, et al. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 2003; 5: 877-889.
3. Abu-Issa R, Waldo K, Kirby ML. Heart fields: one, two or more? Dev Biol 2004; 272: 281-285.
4. Harvey RP. Patterning the vertebrate heart. Nat Rev Genet 2002; 3: 544-556.
5. Srivastava D, Olson EN. A genetic blueprint for cardiac development. Nature 2000; 407: 221-226.
6. Kelly RG, Buckingham ME. The anterior heart-forming field: voyage to the arterial pole of the heart. Trends Genet 2002; 18: 210-216.
7. Buckingham M, Meilhac S, Zaffran S. Building the mammalian heart from two sources of myocardial cells. Nat Rev Genet 2005; 6: 826-835.
8. Laugwitz KL, Moretti A, Lam J, et al. Postnatal Isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 2005; 433: 647-653.
9. Moretti A, Caron L, Nakano A, et al. Multipotent embryonic Isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 2006; 127: 1151-1165.
10. Carmeliet P. Angiogenesis in health and disease. Nat Med 2003; 9: 653-660.
11. Asahara T, Masuda H, Takahashi T, et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999; 85: 221-228.
12. Rehman J, Li J, Orschell CM, March KL. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 2003; 107: 1164-1169.
13. Kinnaird T, Stabile E, Burnett MS, et al. Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004; 94: 678-685.
14. Bischoff J. Cell adhesion and angiogenesis. J Clin Invest 1997; 100: S37-39.
15. Kevil CG, Orr AW, Langston W, et al. Intercellular adhesion molecule-1 (ICAM-1) regulates endothelial cell motility through a nitric oxide-dependent pathway. J Biol Chem 2004; 279: 19230-19238.
16. Garmy-Susini B, Jin H, Zhu Y, et al. Integrin alpha4beta1-VCAM-1-mediated adhesion between endothelial and mural cells is required for blood vessel maturation. J Clin Invest 2005; 115: 1542-1551.
17. Fan Z, Bau B, Yang H, et al. IL-1beta induction of IL-6 and LIF in normal articular human chondrocytes involves the ERK, p38 and NFkappaB signaling pathways. Cytokine 2004; 28: 17-24.
18. Millauer B, Wizigmann-Voos S, Schnurch H, et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993; 72: 835-846.
19. Kappel A, Ronicke V, Damert A, Flamme I, Risau W, Breier G. Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice. Blood 1999; 93: 4284-4292.
20. Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996; 380: 439-442.
21. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143-147.
22. Sun Y, Liang X, Najafi N, et al. Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol 2007; 304: 286-296.
23. Pola R, Ling LE, Aprahamian TR, et al. Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia. Circulation 2003; 108: 479-485.
24. Pola R, Ling LE, Silver M, et al. The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med 2001; 7: 706-711.
25. Kusano KF, Pola R, Murayama T, et al. Sonic hedgehog myocardial gene therapy: tissue repar through transient reconstitution of embryonic signaling. Nat Med 2005; 11: 1197-1204.
26. Hagemeyer CE, Peter K. Ex-vivo thrombolytic gene therapy for vein graft patency: The frontier for development of selective, localised therapeutic approaches. Thromb Haemost 2009; 102: 3-4.
27. Ben-Shoshan J, Schwartz S, Luboshits G, et al. Constitutive expression of HIF-1alpha and HIF-2alpha in bone marrow stromal cells differentially promotes their proangiogenic properties. Stem Cells 2008; 26: 2634-2643.
28. Takakura N, Kidoya H. Maturation of blood vessels by haematopoietic stem cells and progenitor cells: Involvement of apelin/APJ and angiopoietin/Tie2 interactions in vessel caliber size regulation. Thromb Haemost 2009; 101: 999-1005.
29. Risau W. Mechanisms of angiogenesis. Nature 1997; 386: 671-674.
30. Ziegelhoeffer T, Fernandez B, Kostin S, et al. Bone marrow-derived cells do not incorporate into the adult growing vasculature. Circ Res 2004; 94: 230-238.
31. Garlanda C, Parravicini C, Sironi M, et al. Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors. Proc Natl Acad Sci USA 1994; 9: 7291-7295.
32. Cassoni P, Papotti M, Ghè C, et al. Identification, characterization and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines. J Clin Endocrinol Metab 2001; 86: 1738-1745.
33. Muccioli G, Ghè C, Faccani G, et al. Prolactin receptors in human meningiomas: characterization and biological role. J Endocrinol 1997; 153: 365-371.
34. Ghè C, Cassoni P, Catapano F, et al. The antiproliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells. Endocrinology 2002; 143: 484-491.
35. Bahlmann FH, De Groot K, Spandau JM, et al. Erythropoietin regulates endothelial progenitor cells. Blood 2004; 103: 921-926.