메뉴 건너뛰기




Volumn 9, Issue 10, 2009, Pages 880-893

Half a century of L-DOPA

Author keywords

Apoptosis; Dopamine neurons; Glial cells; Glutathione; L DOPA responsive dystonia; MAP kinase; Parkin gene; Parkinson's disease

Indexed keywords

CARBOXYLYASE; CATECHOL METHYLTRANSFERASE; CATECHOLAMINE; LEVODOPA; NERVE GROWTH FACTOR; NEUROTRANSMITTER; SELEGILINE; TOCOPHEROL;

EID: 74249083172     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802609789378263     Document Type: Article
Times cited : (27)

References (88)
  • 1
    • 0000428532 scopus 로고
    • 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists
    • Carlsson, A.; Lindqvist, M.; Magnusson, T. 3,4-Dihydroxyphenylalanine and 5-hydroxytryptophan as reserpine antagonists. Nature 1957, 180, 1200.
    • (1957) Nature , vol.180 , pp. 1200
    • Carlsson, A.1    Lindqvist, M.2    Magnusson, T.3
  • 2
    • 0001145589 scopus 로고
    • Eine neue Amimosäure aus Vitia Faba.
    • Guggenheim, M. Dioxiphenylalanin: Eine neue Amimosäure aus Vitia Faba. Z. Physiol. Chem. 1913, 88, 276-284.
    • (1913) Z. Physiol. Chem , vol.88 , pp. 276-284
    • Guggenheim, M.D.1
  • 5
    • 0000015266 scopus 로고
    • The occurrence, distribution and physiological role of catecholamines in the nervous system
    • Carlsson, A. The occurrence, distribution and physiological role of catecholamines in the nervous system. Pharmacol. Rev. 1959, 11, 490-493.
    • (1959) Pharmacol. Rev , vol.11 , pp. 490-493
    • Carlsson, A.1
  • 7
    • 34250928307 scopus 로고
    • Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system
    • Ehringer, H.; Hornykiewicz, O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system. Klin. Wochenschr. 1960, 38, 1236-1239.
    • (1960) Klin. Wochenschr , vol.38 , pp. 1236-1239
    • Ehringer, H.1    Hornykiewicz, O.2
  • 8
    • 73049129373 scopus 로고
    • The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia
    • Birkmayer, W.; Hornykiewicz, O. The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia. Wien Klin. Wochenschr. 1961, 73, 787-788.
    • (1961) Wien Klin. Wochenschr , vol.73 , pp. 787-788
    • Birkmayer, W.1    Hornykiewicz, O.2
  • 9
    • 0013861887 scopus 로고
    • Treatment of Parkinson's syndrome with L-dopa. A double blind study
    • Fehling, C. Treatment of Parkinson's syndrome with L-dopa. A double blind study. Acta Neurol. Scand. 1966, 42, 367-372.
    • (1966) Acta Neurol. Scand , vol.42 , pp. 367-372
    • Fehling, C.1
  • 10
    • 0006546053 scopus 로고
    • Administration of dihydroxyphenylalanine to Parkinsonian patients
    • McGeer, P.L.; Zeldowicz, L.R. Administration of dihydroxyphenylalanine to Parkinsonian patients. Can. Med. Assoc. J. 1964, 90, 463-466.
    • (1964) Can. Med. Assoc. J , vol.90 , pp. 463-466
    • McGeer, P.L.1    Zeldowicz, L.R.2
  • 11
    • 0002934299 scopus 로고
    • Les catecholamines de la maladie de Parkinson
    • Ajuriaguerra, J. Eds, Georg et Cie: Geneva
    • Barbeau, A.; Sourkes, T.L.; Murphy, G.F. Les catecholamines de la maladie de Parkinson. In: Monoamines et Système Nerveux Central. Ajuriaguerra, J. Eds.; Georg et Cie: Geneva, 1962, 247-267.
    • (1962) Monoamines et Système Nerveux Central , pp. 247-267
    • Barbeau, A.1    Sourkes, T.L.2    Murphy, G.F.3
  • 12
    • 0014208039 scopus 로고
    • Aromatic amino acids and modification of parkinsonism
    • Cotzias, G.C.; Van Woert, M.H.; Schiffer, L.M. Aromatic amino acids and modification of parkinsonism. N. Engl. J. Med. 1967, 276, 374-379.
    • (1967) N. Engl. J. Med , vol.276 , pp. 374-379
    • Cotzias, G.C.1    Van Woert, M.H.2    Schiffer, L.M.3
  • 13
    • 0014673226 scopus 로고
    • Modification of Parkinsonism - chronic treatment with L-dopa
    • Cotzias, G.C.; Papavasiliou, P.S.; Gellene, R. Modification of Parkinsonism - chronic treatment with L-dopa. N. Engl. J. Med. 1969, 280, 337-345.
    • (1969) N. Engl. J. Med , vol.280 , pp. 337-345
    • Cotzias, G.C.1    Papavasiliou, P.S.2    Gellene, R.3
  • 14
    • 0025200843 scopus 로고
    • Levodopa therapy in Parkinson's disease
    • discussion 47-49
    • Koller, W.C.; Hubble, J.P. Levodopa therapy in Parkinson's disease. Neurology 1990, 40, (10 Suppl 3), 40-7, discussion 47-49.
    • (1990) Neurology , vol.40 , Issue.10 SUPPL. 3 , pp. 40-47
    • Koller, W.C.1    Hubble, J.P.2
  • 15
    • 0026444153 scopus 로고
    • Long-acting carbidopa-levodopa in the management of moderate and advanced Parkinson's disease
    • discussion 57-60
    • Hutton, J.T.; Morris, J.L. Long-acting carbidopa-levodopa in the management of moderate and advanced Parkinson's disease. Neurology 1992, 42, 51-56; discussion 57-60.
    • (1992) Neurology , vol.42 , pp. 51-56
    • Hutton, J.T.1    Morris, J.L.2
  • 16
    • 0026449597 scopus 로고
    • Clinical studies with and pharmacokinetic considerations of sustained-release levodopa
    • discussion 57-60
    • LeWitt, P.A. Clinical studies with and pharmacokinetic considerations of sustained-release levodopa. Neurology 1992, 42, 29-32; discussion 57-60.
    • (1992) Neurology , vol.42 , pp. 29-32
    • LeWitt, P.A.1
  • 19
    • 63149090431 scopus 로고    scopus 로고
    • Parkinson's disease: From monogenic forms to genetic susceptibility factors
    • Lesage, S.; Brice, A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet. 2009, 18, 48-59.
    • (2009) Hum. Mol. Genet , vol.18 , pp. 48-59
    • Lesage, S.1    Brice, A.2
  • 20
    • 0025124542 scopus 로고
    • Doparesponsive dystonia: The spectrum of clinical manifestations in a large North American family
    • Nygaard, T.G.; Trugman, J.M.; de Yebenes, J.G.; Fahn, S. Doparesponsive dystonia: the spectrum of clinical manifestations in a large North American family. Neurology 1990, 40, 66-69.
    • (1990) Neurology , vol.40 , pp. 66-69
    • Nygaard, T.G.1    Trugman, J.M.2    de Yebenes, J.G.3    Fahn, S.4
  • 21
    • 0028910911 scopus 로고
    • The gene for hereditary progressive dystonia with marked diurnal fluctuation maps to chromosome 14q
    • Tanaka, H.; Endo, K.; Tsuji, S.; Nygaard, T.G.; Weeks, D.E.; Nomura, Y.; Segawa, M. The gene for hereditary progressive dystonia with marked diurnal fluctuation maps to chromosome 14q. Ann. Neurol. 1995, 37, 405-408.
    • (1995) Ann. Neurol , vol.37 , pp. 405-408
    • Tanaka, H.1    Endo, K.2    Tsuji, S.3    Nygaard, T.G.4    Weeks, D.E.5    Nomura, Y.6    Segawa, M.7
  • 25
    • 18344402736 scopus 로고    scopus 로고
    • Presynaptic mechanisms of motor fluctuations in Parkinson's disease: A probabilistic model
    • de la Fuente-Fernandez, R.; Schulzer, M.; Mak, E.; Calne, D.B.; Stoessl, A.J. Presynaptic mechanisms of motor fluctuations in Parkinson's disease: a probabilistic model. Brain 2004, 127, 888-899.
    • (2004) Brain , vol.127 , pp. 888-899
    • de la Fuente-Fernandez, R.1    Schulzer, M.2    Mak, E.3    Calne, D.B.4    Stoessl, A.J.5
  • 26
    • 9044252959 scopus 로고
    • Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis
    • Nagatsu, T.; Levitt, M.; Udenfriend, S. Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis. J. Biol. Chem. 1964, 239, 2910-2917.
    • (1964) J. Biol. Chem , vol.239 , pp. 2910-2917
    • Nagatsu, T.1    Levitt, M.2    Udenfriend, S.3
  • 27
    • 74249099448 scopus 로고
    • Aspectos farmacocinéticos y farmacodinámicos de las enfermedad de Parkinson
    • Hospital de la y, Eds, Barcelona
    • Garcia de Yébenes, J.; Gervas, J.J.; Muradas, V.; Bazán, E. Aspectos farmacocinéticos y farmacodinámicos de las enfermedad de Parkinson. In: Centenario de la Neurología en España. Hospital de la Santa Creu y Sant Pau, Eds.; Barcelona, 1983, pp. 181-190.
    • (1983) Centenario de la Neurología en España , pp. 181-190
    • Garcia de Yébenes, J.1    Gervas, J.J.2    Muradas, V.3    Bazán, E.4
  • 28
    • 0028878429 scopus 로고
    • The effects of cisapride on plasma L-dopa levels and clinical response in Parkinson's disease
    • Neira, W.D.; Sanchez, V.; Mena, M.A.; de Yebenes, J.G. The effects of cisapride on plasma L-dopa levels and clinical response in Parkinson's disease. Mov. Disord. 1995, 10, 66-70.
    • (1995) Mov. Disord , vol.10 , pp. 66-70
    • Neira, W.D.1    Sanchez, V.2    Mena, M.A.3    de Yebenes, J.G.4
  • 31
    • 0027462802 scopus 로고
    • Levodopa toxicity in foetal rat midbrain neurones in culture: Modulation by ascorbic acid
    • Mena, M.A.; Pardo, B.; Paino, C.L.; De Yebenes, J.G. Levodopa toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid. Neuroreport 1993, 4, 438-440.
    • (1993) Neuroreport , vol.4 , pp. 438-440
    • Mena, M.A.1    Pardo, B.2    Paino, C.L.3    De Yebenes, J.G.4
  • 32
    • 0027362832 scopus 로고
    • Toxic and protective effects of L-dopa on mesencephalic cell cultures
    • Mytilineou, C.; Han, S.K.; Cohen, G. Toxic and protective effects of L-dopa on mesencephalic cell cultures. J. Neurochem. 1993, 61, 1470-1478.
    • (1993) J. Neurochem , vol.61 , pp. 1470-1478
    • Mytilineou, C.1    Han, S.K.2    Cohen, G.3
  • 33
    • 0027268723 scopus 로고
    • Ascorbic acid protects against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line
    • Pardo, B.; Mena, M.A.; Fahn, S.; Garcia de Yebenes, J. Ascorbic acid protects against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line. Mov. Disord. 1993, 8, 278-284.
    • (1993) Mov. Disord , vol.8 , pp. 278-284
    • Pardo, B.1    Mena, M.A.2    Fahn, S.3    Garcia de Yebenes, J.4
  • 34
    • 0029053242 scopus 로고
    • Toxic effects of L-DOPA on mesencephalic cell cultures: Protection with antioxidants
    • Pardo, B.; Mena, M.A.; Casarejos, M.J.; Paino, C.L.; De Yebenes, J.G. Toxic effects of L-DOPA on mesencephalic cell cultures: protection with antioxidants. Brain Res. 1995, 682, 133-143.
    • (1995) Brain Res , vol.682 , pp. 133-143
    • Pardo, B.1    Mena, M.A.2    Casarejos, M.J.3    Paino, C.L.4    De Yebenes, J.G.5
  • 35
    • 0028857498 scopus 로고
    • L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells
    • Pardo, B.; Mena, M.A.; de Yebenes, J.G. L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells. J. Neurochem. 1995, 64, 576-582.
    • (1995) J. Neurochem , vol.64 , pp. 576-582
    • Pardo, B.1    Mena, M.A.2    de Yebenes, J.G.3
  • 36
    • 0019447228 scopus 로고
    • Long-term administration of L-DOPA does not damage dopaminergic neurons in the mouse
    • Hefti, F.; Melamed, E.; Bhawan, J.; Wurtman, R.J. Long-term administration of L-DOPA does not damage dopaminergic neurons in the mouse. Neurology 1981, 31, 1194-1195.
    • (1981) Neurology , vol.31 , pp. 1194-1195
    • Hefti, F.1    Melamed, E.2    Bhawan, J.3    Wurtman, R.J.4
  • 37
    • 0031969137 scopus 로고    scopus 로고
    • Welcome news about levodopa, but uncertainty remains
    • Fahn, S. Welcome news about levodopa, but uncertainty remains. Ann. Neurol. 1998, 43, 551-554.
    • (1998) Ann. Neurol , vol.43 , pp. 551-554
    • Fahn, S.1
  • 38
    • 0031968959 scopus 로고    scopus 로고
    • Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions
    • Murer, M.G.; Dziewczapolski, G.; Menalled, L.B.; Garcia, M.C.; Agid, Y.; Gershanik, O.; Raisman-Vozari, R. Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions. Ann. Neurol. 1998, 43, 561-575.
    • (1998) Ann. Neurol , vol.43 , pp. 561-575
    • Murer, M.G.1    Dziewczapolski, G.2    Menalled, L.B.3    Garcia, M.C.4    Agid, Y.5    Gershanik, O.6    Raisman-Vozari, R.7
  • 39
    • 0029915162 scopus 로고    scopus 로고
    • Glia conditioned medium protects fetal rat midbrain neurones in culture from L-DOPA toxicity
    • Mena, M.A.; Casarejos, M.J.; Carazo, A.; Paino, C.L.; Garcia de Yebenes, J. Glia conditioned medium protects fetal rat midbrain neurones in culture from L-DOPA toxicity. Neuroreport 1996, 7, 441-445.
    • (1996) Neuroreport , vol.7 , pp. 441-445
    • Mena, M.A.1    Casarejos, M.J.2    Carazo, A.3    Paino, C.L.4    Garcia de Yebenes, J.5
  • 40
    • 0030880246 scopus 로고    scopus 로고
    • Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms
    • Mena, M.A.; Casarejos, M.J.; Carazo, A.; Paino, C.L.; Garcia de Yebenes, J. Glia protect fetal midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms. J. Neural. Transm. 1997, 104, 317-328.
    • (1997) J. Neural. Transm , vol.104 , pp. 317-328
    • Mena, M.A.1    Casarejos, M.J.2    Carazo, A.3    Paino, C.L.4    Garcia de Yebenes, J.5
  • 41
    • 0002948770 scopus 로고    scopus 로고
    • The critical factor for L-DOPA toxicity on DA neurons is glia
    • Castellano, B, Gonzalez, B, Nieto-Sampedro, M. Eds, Kluwer Academic Publishers: Boston
    • Mena, M.A.; Casarejos, M.J.; Alcazar, A.; Herranz, A.; Paino, C.L.; De Yebenes, G.J. The critical factor for L-DOPA toxicity on DA neurons is glia. In: Understanding Glia Cells; Castellano, B.; Gonzalez, B.; Nieto-Sampedro, M. Eds.; Kluwer Academic Publishers: Boston, 1998, pp. 213-232.
    • (1998) Understanding Glia Cells , pp. 213-232
    • Mena, M.A.1    Casarejos, M.J.2    Alcazar, A.3    Herranz, A.4    Paino, C.L.5    De Yebenes, G.J.6
  • 42
    • 0030931665 scopus 로고    scopus 로고
    • Neurotrophic effects of LDOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures
    • Mena, M.A.; Davila, V.; Sulzer, D. Neurotrophic effects of LDOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. J. Neurochem. 1997, 69, 1398-1408.
    • (1997) J. Neurochem , vol.69 , pp. 1398-1408
    • Mena, M.A.1    Davila, V.2    Sulzer, D.3
  • 43
    • 0030943110 scopus 로고    scopus 로고
    • Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture
    • Mena, M.A.; Khan, U.; Togasaki, D.M.; Sulzer, D.; Epstein, C.J.; Przedborski, S. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. J. Neurochem. 1997, 69, 21-33.
    • (1997) J. Neurochem , vol.69 , pp. 21-33
    • Mena, M.A.1    Khan, U.2    Togasaki, D.M.3    Sulzer, D.4    Epstein, C.J.5    Przedborski, S.6
  • 44
    • 0031726193 scopus 로고    scopus 로고
    • A synergistic neurotrophic response to l-dihydroxyphenylalanine and nerve growth factor
    • Mena, M.A.; Davila, V.; Bogaluvsky, J.; Sulzer, D. A synergistic neurotrophic response to l-dihydroxyphenylalanine and nerve growth factor. Mol. Pharmacol. 1998, 54, 678-686.
    • (1998) Mol. Pharmacol , vol.54 , pp. 678-686
    • Mena, M.A.1    Davila, V.2    Bogaluvsky, J.3    Sulzer, D.4
  • 45
    • 0034905714 scopus 로고    scopus 로고
    • L-DOPA and glia-conditioned medium have additive effects on tyrosine hydroxylase expression in human catecholamine-rich neuroblastoma NB69 cells
    • Rodriguez-Martin, E.; Canals, S.; Casarejos, M.J.; de Bernardo, S.; Handler, A.; Mena, M.A. L-DOPA and glia-conditioned medium have additive effects on tyrosine hydroxylase expression in human catecholamine-rich neuroblastoma NB69 cells. J. Neurochem. 2001, 78, 535-545.
    • (2001) J. Neurochem , vol.78 , pp. 535-545
    • Rodriguez-Martin, E.1    Canals, S.2    Casarejos, M.J.3    de Bernardo, S.4    Handler, A.5    Mena, M.A.6
  • 47
    • 0041837545 scopus 로고    scopus 로고
    • Glia-conditioned medium induces de novo synthesis of tyrosine hydroxylase and increases dopamine cell survival by differential signaling pathways
    • de Bernardo, S.; Canals, S.; Casarejos, M.J.; Rodriguez-Martin, E.; Mena, M.A. Glia-conditioned medium induces de novo synthesis of tyrosine hydroxylase and increases dopamine cell survival by differential signaling pathways. J. Neurosci. Res. 2003, 73, 818-830.
    • (2003) J. Neurosci. Res , vol.73 , pp. 818-830
    • de Bernardo, S.1    Canals, S.2    Casarejos, M.J.3    Rodriguez-Martin, E.4    Mena, M.A.5
  • 51
    • 0024446303 scopus 로고
    • Deprenyl suppresses the oxidant stress associated with increased dopamine turnover
    • Cohen, G.; Spina, M.B. Deprenyl suppresses the oxidant stress associated with increased dopamine turnover. Ann. Neurol. 1989, 26, 689-690.
    • (1989) Ann. Neurol , vol.26 , pp. 689-690
    • Cohen, G.1    Spina, M.B.2
  • 52
    • 0028917028 scopus 로고
    • Selegiline induces "trophic-like" rescue of dying neurons without MAO inhibition
    • Tatton, W.G.; Ansari, K.; Ju, W.; Salo, P.T.; Yu, P.H. Selegiline induces "trophic-like" rescue of dying neurons without MAO inhibition. Adv. Exp. Med. Biol. 1995, 363, 15-16.
    • (1995) Adv. Exp. Med. Biol , vol.363 , pp. 15-16
    • Tatton, W.G.1    Ansari, K.2    Ju, W.3    Salo, P.T.4    Yu, P.H.5
  • 53
    • 0036719861 scopus 로고    scopus 로고
    • Neuroprotection by propargylamines in Parkinson's disease: Suppression of apoptosis and induction of prosurvival genes
    • Maruyama, W.; Akao, Y.; Carrillo, M.C.; Kitani, K.; Youdium, M.B.; Naoi, M. Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes. Neurotoxicol. Teratol. 2002, 24, 675-682.
    • (2002) Neurotoxicol. Teratol , vol.24 , pp. 675-682
    • Maruyama, W.1    Akao, Y.2    Carrillo, M.C.3    Kitani, K.4    Youdium, M.B.5    Naoi, M.6
  • 54
    • 0141957304 scopus 로고    scopus 로고
    • L-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria
    • De Marchi, U.; Pietrangeli, P.; Marcocci, L.; Mondovi, B.; Toninello, A. L-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria. Biochem. Pharmacol. 2003, 66, 1749-1754.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 1749-1754
    • De Marchi, U.1    Pietrangeli, P.2    Marcocci, L.3    Mondovi, B.4    Toninello, A.5
  • 55
    • 0018148688 scopus 로고
    • Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro
    • Graham, D.G.; Tiffany, S.M.; Bell, W.R., Jr.; Gutknecht, W.F. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol. Pharmacol. 1978, 14, 644-653.
    • (1978) Mol. Pharmacol , vol.14 , pp. 644-653
    • Graham, D.G.1    Tiffany, S.M.2    Bell Jr., W.R.3    Gutknecht, W.F.4
  • 56
    • 0024399943 scopus 로고
    • 6-Hydroxydopamine toxicity to dopamine neurons in culture: Potentiation by the addition of superoxide dismutase and N-acetylcysteine
    • Mytilineou, C.; Danias, P. 6-Hydroxydopamine toxicity to dopamine neurons in culture: potentiation by the addition of superoxide dismutase and N-acetylcysteine. Biochem. Pharmacol. 1989, 38, 1872-1875.
    • (1989) Biochem. Pharmacol , vol.38 , pp. 1872-1875
    • Mytilineou, C.1    Danias, P.2
  • 57
    • 0034194081 scopus 로고    scopus 로고
    • Ascorbate regulation and its neuroprotective role in the brain
    • Rice, M.E. Ascorbate regulation and its neuroprotective role in the brain. Trends. Neurosci. 2000, 23, 209-216.
    • (2000) Trends. Neurosci , vol.23 , pp. 209-216
    • Rice, M.E.1
  • 58
    • 0025770366 scopus 로고
    • Ascorbic acid in mesencephalic cultures: Effects on dopaminergic neuron development
    • Kalir, H.H.; Mytilineou, C. Ascorbic acid in mesencephalic cultures: effects on dopaminergic neuron development. J. Neurochem. 1991, 57, 458-464.
    • (1991) J. Neurochem , vol.57 , pp. 458-464
    • Kalir, H.H.1    Mytilineou, C.2
  • 59
    • 0026520111 scopus 로고
    • NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats
    • Nistico, G.; Ciriolo, M.R.; Fiskin, K.; Iannone, M.; De Martino, A.; Rotilio, G. NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats. Free Radic. Biol. Med. 1992, 12, 177-181.
    • (1992) Free Radic. Biol. Med , vol.12 , pp. 177-181
    • Nistico, G.1    Ciriolo, M.R.2    Fiskin, K.3    Iannone, M.4    De Martino, A.5    Rotilio, G.6
  • 60
    • 0025865790 scopus 로고
    • Dopamine increases the expression of tyrosine hydroxylase and aromatic amino acid decarboxylase in primary cultures of fetal neurons
    • De Vitry, F.; Hillion, J.; Catelon, J.; Thibault, J.; Benoliel, J.J.; Hamon, M. Dopamine increases the expression of tyrosine hydroxylase and aromatic amino acid decarboxylase in primary cultures of fetal neurons. Brain Res. Dev. Brain. Res. 1991, 59, 123-131.
    • (1991) Brain Res. Dev. Brain. Res , vol.59 , pp. 123-131
    • De Vitry, F.1    Hillion, J.2    Catelon, J.3    Thibault, J.4    Benoliel, J.J.5    Hamon, M.6
  • 61
    • 0002642680 scopus 로고
    • Neurotransmitters as neurotrophic factors
    • Fallon, J.H, Loughlin, S.E. Eds, Academic Press: San Diego
    • Leslie, F.M. Neurotransmitters as neurotrophic factors. In: Neurotrophic factors. Fallon, J.H.; Loughlin, S.E. Eds.; Academic Press: San Diego, 1993, pp. 565-598.
    • (1993) Neurotrophic factors , pp. 565-598
    • Leslie, F.M.1
  • 62
    • 0025805548 scopus 로고
    • 2,4,5-trihydroxyphenylalanine in solution forms a non-N-methyl-D-aspartate glutamatergic agonist and neurotoxin
    • Rosenberg, P.A.; Loring, R.; Xie, Y.; Zaleskas, V.; Aizenman, E. 2,4,5-trihydroxyphenylalanine in solution forms a non-N-methyl-D-aspartate glutamatergic agonist and neurotoxin. Proc. Natl. Acad. Sci. USA 1991, 88, 4865-4869.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4865-4869
    • Rosenberg, P.A.1    Loring, R.2    Xie, Y.3    Zaleskas, V.4    Aizenman, E.5
  • 63
    • 57449104707 scopus 로고    scopus 로고
    • Glial cells as players in parkinsonism: The "good," the "bad," and the "mysterious" glia
    • Mena, M.A.; Garcia de Yebenes, J. Glial cells as players in parkinsonism: the "good," the "bad," and the "mysterious" glia. Neuroscientist 2008, 14, 544-560.
    • (2008) Neuroscientist , vol.14 , pp. 544-560
    • Mena, M.A.1    Garcia de Yebenes, J.2
  • 65
    • 0027302371 scopus 로고
    • Glutathione disulfide (GSSG) as a marker of oxidative injury to brain mitochondria
    • Werner, P.; Cohen, G. Glutathione disulfide (GSSG) as a marker of oxidative injury to brain mitochondria. Ann. N. Y. Acad. Sci. 1993, 679, 364-369.
    • (1993) Ann. N. Y. Acad. Sci , vol.679 , pp. 364-369
    • Werner, P.1    Cohen, G.2
  • 66
    • 0027434596 scopus 로고
    • Glutathione peroxidase, glial cells and Parkinson's disease
    • Damier, P.; Hirsch, E.C.; Zhang, P.; Agid, Y.; Javoy-Agid, F. Glutathione peroxidase, glial cells and Parkinson's disease. Neurosci. 1993, 52, 1-6.
    • (1993) Neurosci , vol.52 , pp. 1-6
    • Damier, P.1    Hirsch, E.C.2    Zhang, P.3    Agid, Y.4    Javoy-Agid, F.5
  • 67
    • 0024324666 scopus 로고
    • Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons
    • Raps, S.P.; Lai, J.C.; Hertz, L.; Cooper, A.J. Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res. 1989, 493, 398-401.
    • (1989) Brain Res , vol.493 , pp. 398-401
    • Raps, S.P.1    Lai, J.C.2    Hertz, L.3    Cooper, A.J.4
  • 68
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara, J.I.; Miura, K.; Bannai, S. Maintenance of neuronal glutathione by glial cells. J. Neurochem. 1993, 61, 1672-1676.
    • (1993) J. Neurochem , vol.61 , pp. 1672-1676
    • Sagara, J.I.1    Miura, K.2    Bannai, S.3
  • 69
    • 0028903513 scopus 로고
    • Protection from oxidation enhances the survival of cultured mesencephalic neurons
    • Colton, C.A.; Pagan, F.; Snell, J.; Colton, J.S.; Cummins, A.; Gilbert, D.L. Protection from oxidation enhances the survival of cultured mesencephalic neurons. Exp. Neurol. 1995, 132, 54-61.
    • (1995) Exp. Neurol , vol.132 , pp. 54-61
    • Colton, C.A.1    Pagan, F.2    Snell, J.3    Colton, J.S.4    Cummins, A.5    Gilbert, D.L.6
  • 70
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han, S.K.; Mytilineou, C.; Cohen, G. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem. 1996, 66, 501-510.
    • (1996) J. Neurochem , vol.66 , pp. 501-510
    • Han, S.K.1    Mytilineou, C.2    Cohen, G.3
  • 71
    • 0028864695 scopus 로고
    • N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent
    • Yan, C.Y.; Ferrari, G.; Greene, L.A. N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent. J. Biol. Chem. 1995, 270, 26827-26832.
    • (1995) J. Biol. Chem , vol.270 , pp. 26827-26832
    • Yan, C.Y.1    Ferrari, G.2    Greene, L.A.3
  • 72
    • 0028916027 scopus 로고
    • N-acetylcysteine (D- and Lstereoisomers) prevents apoptotic death of neuronal cells
    • Ferrari, G.; Yan, C.Y.; Greene, L.A. N-acetylcysteine (D- and Lstereoisomers) prevents apoptotic death of neuronal cells. J. Neurosci. 1995, 15, 2857-2866.
    • (1995) J. Neurosci , vol.15 , pp. 2857-2866
    • Ferrari, G.1    Yan, C.Y.2    Greene, L.A.3
  • 73
    • 0027185713 scopus 로고
    • Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease
    • Jenner, P. Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease. Acta Neurol. Scand. Suppl. 1993, 146, 6-13.
    • (1993) Acta Neurol. Scand. Suppl , vol.146 , pp. 6-13
    • Jenner, P.1
  • 74
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian, J.; Dexter, D.T.; Lees, A.J.; Daniel, S.; Agid, Y.; Javoy-Agid, F.; Jenner, P.; Marsden, C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 1994, 36, 348-355.
    • (1994) Ann. Neurol , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Javoy-Agid, F.6    Jenner, P.7    Marsden, C.D.8
  • 75
    • 0028928605 scopus 로고
    • Reduced and oxidized forms of glutathione and alpha-tocopherol in the cerebrospinal fluid of parkinsonian patients: Comparison between before and after L-dopa treatment
    • Tohgi, H.; Abe, T.; Saheki, M.; Hamato, F.; Sasaki, K.; Takahashi, S. Reduced and oxidized forms of glutathione and alpha-tocopherol in the cerebrospinal fluid of parkinsonian patients: comparison between before and after L-dopa treatment. Neurosci. Lett. 1995, 184, 21-24.
    • (1995) Neurosci. Lett , vol.184 , pp. 21-24
    • Tohgi, H.1    Abe, T.2    Saheki, M.3    Hamato, F.4    Sasaki, K.5    Takahashi, S.6
  • 76
    • 0028912476 scopus 로고
    • Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
    • Zhou, Q.Y.; Quaife, C.J.; Palmiter, R.D. Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature 1995, 374, 640-643.
    • (1995) Nature , vol.374 , pp. 640-643
    • Zhou, Q.Y.1    Quaife, C.J.2    Palmiter, R.D.3
  • 77
    • 0028935117 scopus 로고
    • Noradrenaline is essential for mouse fetal development
    • Thomas, S.A.; Matsumoto, A.M.; Palmiter, R.D. Noradrenaline is essential for mouse fetal development. Nature 1995, 374, 643-646.
    • (1995) Nature , vol.374 , pp. 643-646
    • Thomas, S.A.1    Matsumoto, A.M.2    Palmiter, R.D.3
  • 82
    • 55249104924 scopus 로고    scopus 로고
    • On the pathogenesis and neuroprotective treatment of Parkinson disease: What have we learned from the genetic forms of this disease?
    • Mena, M.A.; Rodriguez-Navarro, J.A.; Ros, R.; de Yebenes, J.G. On the pathogenesis and neuroprotective treatment of Parkinson disease: what have we learned from the genetic forms of this disease? Curr. Med. Chem. 2008, 15, 2305-2320.
    • (2008) Curr. Med. Chem , vol.15 , pp. 2305-2320
    • Mena, M.A.1    Rodriguez-Navarro, J.A.2    Ros, R.3    de Yebenes, J.G.4
  • 83
    • 23844529467 scopus 로고    scopus 로고
    • Differential effects of l-DOPA on monoamine metabolism, cell survival and glutathione production in midbrain neuronal-enriched cultures from parkin knockout and wild-type mice
    • Casarejos, M.J.; Solano, R.M.; Menendez, J.; Rodriguez-Navarro, J.A.; Correa, C.; Garcia de Yebenes, J.; Mena, M.A. Differential effects of l-DOPA on monoamine metabolism, cell survival and glutathione production in midbrain neuronal-enriched cultures from parkin knockout and wild-type mice. J. Neurochem. 2005, 94, 1005-1014.
    • (2005) J. Neurochem , vol.94 , pp. 1005-1014
    • Casarejos, M.J.1    Solano, R.M.2    Menendez, J.3    Rodriguez-Navarro, J.A.4    Correa, C.5    Garcia de Yebenes, J.6    Mena, M.A.7
  • 84
    • 0021332709 scopus 로고
    • Aromatic L-amino acid decarboxylase in the rat brain: Immunocytochemical localization in neurons of the brain stem
    • Jaeger, C.B.; Ruggiero, D.A.; Albert, V.R.; Park, D.H.; Joh, T.H.; Reis, D.J. Aromatic L-amino acid decarboxylase in the rat brain: immunocytochemical localization in neurons of the brain stem. Neurosci. 1984, 11, 691-713.
    • (1984) Neurosci , vol.11 , pp. 691-713
    • Jaeger, C.B.1    Ruggiero, D.A.2    Albert, V.R.3    Park, D.H.4    Joh, T.H.5    Reis, D.J.6
  • 85
    • 0035125530 scopus 로고    scopus 로고
    • Endogenously released DOPA is a causal factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rat striata
    • Furukawa, N.; Arai, N.; Goshima, Y.; Miyamae, T.; Ohshima, E.; Suzuki, F.; Fujita, K.; Misu, Y. Endogenously released DOPA is a causal factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rat striata. J. Neurochem. 2001, 76, 815-824.
    • (2001) J. Neurochem , vol.76 , pp. 815-824
    • Furukawa, N.1    Arai, N.2    Goshima, Y.3    Miyamae, T.4    Ohshima, E.5    Suzuki, F.6    Fujita, K.7    Misu, Y.8
  • 86
    • 12244301573 scopus 로고    scopus 로고
    • L-3,4-Dihydroxyphenylalanine as a neurotransmitter candidate in the central nervous system
    • Misu, Y.; Kitahama, K.; Goshima, Y. L-3,4-Dihydroxyphenylalanine as a neurotransmitter candidate in the central nervous system. Pharmacol. Ther. 2003, 97, 117-137.
    • (2003) Pharmacol. Ther , vol.97 , pp. 117-137
    • Misu, Y.1    Kitahama, K.2    Goshima, Y.3
  • 87
    • 0028988924 scopus 로고
    • L-dihydroxyphenylalanine and its decarboxylase: New ideas on their neuroregulatory roles
    • Opacka-Juffry, J.; Brooks, D.J. L-dihydroxyphenylalanine and its decarboxylase: new ideas on their neuroregulatory roles. Mov. Disord. 1995, 10, 241-249.
    • (1995) Mov. Disord , vol.10 , pp. 241-249
    • Opacka-Juffry, J.1    Brooks, D.J.2
  • 88
    • 74249083803 scopus 로고    scopus 로고
    • Mena, M.A.; Casarejos, M.J.; Rodríguez-Martín, E.; Solano, R.M.; Menéndez, J.; García de Yébenes, J. Neuroprotective and neurotoxic effects of L-DOPA in rat midbrain dopaminergic neurons in culture. in: neurobiology of DOPA as a neurotransmitter: Misu, Y.; Goshima, Y.; Eds.; Taylor and Francis Group: New York, 2006, pp. 303-319.
    • Mena, M.A.; Casarejos, M.J.; Rodríguez-Martín, E.; Solano, R.M.; Menéndez, J.; García de Yébenes, J. Neuroprotective and neurotoxic effects of L-DOPA in rat midbrain dopaminergic neurons in culture. in: neurobiology of DOPA as a neurotransmitter: Misu, Y.; Goshima, Y.; Eds.; Taylor and Francis Group: New York, 2006, pp. 303-319.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.