Functional consequences of homocysteinylation of the elastic fiber proteins fibrillin-1 and tropoelastin

Journal of Biological Chemistry

Volumn 285, Issue 2, 2010, Pages 1188-1198

  Hubmacher, Dirk ^a   Cirulis, Judith T ^b   Miao, Ming ^b   Keeley, Fred W ^b   Reinhardt, Dieter P ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CLINICAL SYMPTOMS; CONNECTIVE TISSUES; CYSTEINE RESIDUES; DIFFERENT ORIGINS; ELASTIC FIBER; ELASTIN-LIKE POLYPEPTIDES; ELEVATED PLASMA; FIBRILLIN-1; FUNCTIONAL PROPERTIES; HOMOCYSTEINES; HUMAN DERMAL FIBROBLASTS; LONG BONE; MARFAN SYNDROME; MICRO-FIBRILS; MULTIMERIZATION; SELF-INTERACTIONS; SYNTHASES; TROPOELASTIN;

CELL CULTURE; COLLAGEN; MUSCULOSKELETAL SYSTEM; POLYPEPTIDES;

BIOMATERIALS;

CYSTATHIONINE BETA SYNTHASE; FIBRILLIN 1; HOMOCYSTEINE; POLYPEPTIDE; RECOMBINANT PROTEIN; TROPOELASTIN;

ARTICLE; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; CHILD; CONTROLLED STUDY; ELASTIC FIBER; EXTRACELLULAR MATRIX; FIBROBLAST; HOMOCYSTINURIA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PHENOTYPE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; SOLID;

CELLS, CULTURED; CYSTATHIONINE BETA-SYNTHASE; ECTOPIA LENTIS; FIBROBLASTS; HOMOCYSTEINE; HOMOCYSTINURIA; HUMANS; MARFAN SYNDROME; MICROFILAMENT PROTEINS; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; SCOLIOSIS; TROPOELASTIN;

EID: 74049160847     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.021246     Document Type: Article

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