Scale-up fermentation of echinocandin type antibiotic FR901379

Journal of Bioscience and Bioengineering

Volumn 109, Issue 2, 2010, Pages 138-144

  Kanda, Munekazu ^a   Yamamoto, Eiji ^a   Hayashi, Akihiro ^a   Yabutani, Tetsuya ^a   Yamashita, Michio ^a   Honda, Hiroyuki ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Antibiotics; Fermentation; kLa; Medium design; Scale up

Indexed keywords

AMMONIUM SULFATE; CARBON SOURCE; CORN STEEP LIQUOR; ECHINOCANDIN; FERMENTORS; HIGH REPRODUCIBILITY; HIGH-LEVEL PRODUCTION; INDUSTRIAL-SCALE PRODUCTION; LIPOPEPTIDES; MEDIUM DESIGN; MIXING TIME; MUTANT STRAIN; ORGANIC NITROGEN; REPRODUCIBILITIES; SCALE-UP;

AMMONIUM COMPOUNDS; ANTIBIOTICS; FERMENTATION; VISCOSITY;

FERMENTERS;

AMMONIUM SULFATE; ANTIBIOTIC AGENT; ECHINOCANDIN; FR 901379; MICAFUNGIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM CULTURE; CARBON SOURCE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; COLEOPHOMA EMPETRI; CORN; COTTON; CULTURE MEDIUM; FERMENTATION TECHNIQUE; FLOUR; MICROORGANISM; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCALE UP; SOYBEAN; VISCOSITY; WHEAT GERM;

ANTI-BACTERIAL AGENTS; ASCOMYCOTA; BIOREACTORS; BIOTECHNOLOGY; ECHINOCANDINS; FERMENTATION; LIPOPEPTIDES; PEPTIDES, CYCLIC; VISCOSITY;

COLEOPHOMA EMPETRI; ZEA MAYS;

EID: 74049143585     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2009.07.019     Document Type: Article

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