Scale up of a viscous fungal fermentation: Application of scale-up criteria with regime analysis and operating boundary conditions

Biotechnology and Bioengineering

Volumn 96, Issue 2, 2007, Pages 307-317

  Pollard, D J ^a   Kirschner, T F ^a   Hunt, G R ^a   Tong, I T ^a   Stieber, R ^a   Salmon, P M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Fermentation; Glarea lozoyensis; kLa; Mixing time; Regime analysis; Scale up

Indexed keywords

BLENDING; BOUNDARY CONDITIONS; CONCENTRATION (PROCESS); FERMENTATION; MIXING; VISCOSITY;

DISSOLVED OXYGEN TENSION (DOT); GLAREA LOZOYENSIS; MIXING TIME; REGIME ANALYSIS;

FUNGI;

DISSOLVED OXYGEN; PNEUMOCANDIN DERIVATIVE;

AGITATION; ARTICLE; FERMENTATION; FUNGUS GROWTH; HYDROXYLATION; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN SATURATION; OXYGEN TENSION; SCALE UP; SHEAR RATE;

ASCOMYCOTA; BIOREACTORS; FERMENTATION; MOLECULAR STRUCTURE; OXYGEN; PEPTIDES, CYCLIC; VISCOSITY;

FUNGI; GLAREA LOZOYENSIS;

EID: 33846934666     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21112     Document Type: Article

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