The Role of Unsterile Injections in the HIV Pandemic

Global HIV/AIDS Medicine

Volumn , Issue , 2008, Pages 755-767

  Drucker, Ernest ^a   Apetrei, Cristian ^b   Heimer, Robert ^c   Marx, Preston ^b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 74049126819     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-4160-2882-6.50071-X     Document Type: Chapter

References (115)

1. Frank C, Mohamed MK, Strickland GT, et al. The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt. Lancet 2000, 355:887-891.
2. Helpern M An epidemic of aestivo-autumnal and Quartan malaria among drug addicts in New York City transmitted by the use of contaminated hypodermic syringes. Publ Health Rpts 1934, 49:421-423.
3. Friedland GH, Harris C, Butkus-Small C, et al. Intravenous drug abusers and the acquired immunodeficiency syndrome (AIDS). Demographic, drug use, and needle-sharing patterns. Arch Int Med 1985, 145:1413-1417.
4. Drucker E, Alcabes PG, Marx PA The injection century: massive unsterile injections and the emergence of human pathogens. Lancet 2001, 358:1989-1992.
5. The Echo 1991, 11:1. Becton-Dickinson Corp, Franklin Lakes, NJ.
6. The Echo 1991, 11:2. Becton-Dickinson Corp, Franklin Lakes, NJ.
7. The Echo 1991, 11:3. Becton-Dickinson Corp, Franklin Lakes, NJ.
8. US disposable needles, syringes, and related products mkt 1996, Frost and Sullivan Corp, Frost and Sullivan, New York.
9. Hayward EG Penicillin and other antibiotics. Chemurgic Papers, No 13 1949, National Farm Chemurgic Council, New York.
10. Hewitt WL Penicillin: historical impact on infection control. Ann NY Acad Sci 1967, 145:212-215.
11. Cardo DM, Bell DM Bloodborne pathogen transmission in health care workers: risks and prevention strategies. Infect Dis Clin N Am 1997, 25:144-154.
12. Hauri A, Armstrong G, Hutin Y The global burden of disease attributable to contaminated healthcare equipment. Int J STD AIDS 2004, 15:7-16.
13. Unsafe injections practices and transmission of bloodborne pathogens. Bull WHO 1999, 77:787-819. WHO.
14. Short LJ, Bell DM Risk of occupational infection with blood-borne pathogens in operating and delivery room settings. Am J Infect Control 1993, 21:343-350.
15. Abdala N, Stephens PC, Griffith BP, et al. Survival of human immunodeficiency virus type 1 in syringes. J Acquir Immune Defic Syndr Hum Retrovir 1999, 20:73-80.
16. Abdala N, Reyes R, Carney JM, et al. Survival of HIV-1 in syringes: Effects of temperature during storage. Subst Use Misuse 2000, 35:1-19.
17. Kaplan EH, Heimer R A model-based estimate of HIV infectivity via needle sharing. J Acquir Immune Defic Syndr 1992, 5:1116-1118.
18. Hudgens MGIM, Longini ME, Halloran K, et al. Estimating the transmission probability of human immunodeficiency virus in injecting drug users in Thailand. J R Stat Soc Appl Stat 2001, 50(Part 1):1-14.
19. Rich JD, Dickinson BP, Carney JM, et al. The presence of HIV antibodies and absence of HIV DNA in syringes used for non-intravenous injection. AIDS 1998, 12:2345-2350.
20. Whyte SR, van der Geest S Injections: issues and methods for anthropological research. Medicines: Meanings and context 1994, HAIN, Quezon City. N.L. Etkin, M.L. Tan (Eds.).
21. Health and disease in tribal societies, CIBA Foundation Symposium No. 49 1977, CIBA, Elsevier, Oxford.
22. Pye's surgical handicraft 1962, 1. Wright, Bristol. H. Baily (Ed.).
23. Wyatt HV The popularity of injections in the Third World: origins and consequences for poliomyelitis. Soc Sci Med 1984, 19:911-915.
24. Reeler AV Injections: A fatal attraction. Soc Sci Med 1990, 31:1119-1125.
25. Simonsen L, Kane A, Lloyd J, et al. Unsafe injections in the developing world and transmission of blood borne pathogens: a review. Bull World Health Organ 1999, 77:789-800.
26. Huytin YJ, Hauri AM, Armstrong GL Use of injections in health care settings worldwide, 2000: literature review and regional estimates. Br Med J 2003, 327:1075.
27. WHO. World Health Report 2004.
28. HIV Transmission in health care settings 2004, PHR White paper, Physicians for Human Rights, Cambridge, MA.
29. Frank C, Mohamed MK, Strickland GT, Lavanchy D, Arthur RR, Magder LS, et al. The role of parenteral antischistosmal therapy in the spread of hepatitis C virus in Egypt. Lancet 2000, 355:887-891.
30. Madhava V, Burgess C, Drucker E Epidemiology of chronic of hepatitis C virus infection in sub-Saharan Africa. Lancet Infect Dis 2002, 2:293-302.
31. Kermode MA. Safer Injections, fewer injections: management of needles and sharps and occupational blood exposure in rural north Indian health settings. Unpublished. PhD Dissertation, Deakin Univeristy; 2003.
32. Oliver R, Atmore A Africa since 1800 1977, Cambridge University Press, Cambridge. 2nd edn.
33. Alland A Adaptation in cultural evolution: an approach to medical anthropology 1970, Columbia University, NY.
34. Hochschild A King Leopold's ghost 1998, Houghton Mifflin, New York.
35. Birungi H, Asiimwe D, Whyte SR Injection use and practices in Uganda 1994, WHO Action Program on Essential Drugs, Geneva.
36. Whyte SR Penicillin, battery acid and sacrifice: Cures and causes in Nyole medicine. Soc Sci Med 1982, 16:2055-2056.
37. Gumodoka B, Vos J, Berge ZA, et al. Injection practices in Mwanza region, Tanzania: prescriptions, patient demand and sterility. Trop Med Int Health 1996, 1:874-880.
38. van der Geest S The illegal distribution of Western medicines in developing countries: pharmacists, drug peddlers, injection doctors and others: a bibliographic exploration. Med Anthrop 1982, 6:197-219.
39. Miller HM, Singh RN Urbanization during the postcolonial days. Urbanization in Africa 1994, Westport Greenwood Press. J.D. Tarver (Ed.).
40. Hendrick R Colonialism, health and illness in French Equatorial Africa (1885-1935) 1994, African Studies Association Press, Atlanta.
41. Quataert J, Liu TP, Hunt NR, et al. (eds). Gendered colonialisms in African history 1997, Blackwell, Oxford.
42. UNICEF in Africa South of the Sahara: A historical perspective 1987, UNICEF, UNICEF, Geneva.
43. Yamousssoukro Declaration, 1994. WHO/EPI Update No. 2794/10283.
44. Schneider WH, Drucker E Blood transfusions in the early years of AIDS in sub-Saharan Africa. Am J Publ Health 2006, 96:984-994.
45. Brewer D, Brody S, Drucker E, et al. Mounting anomalies in the epidemiology of HIV in Africa: Cry the Beloved Paradigm. Int J STD AIDS 2003, 14:144-147.
46. Lopman BA, et al. Individual level injection history: a lack of association with HIV incidence in rural Zimbabwe. PLoS Med 2005, 2143-2145.
47. Drucker E, Nadelmann E, Newman RG, et al. Harm reduction: pragmatic drug policies for public health and safety. Substance abuse: A comprehensive textbook 2004, Lippincott Williams and Wilkins, Hagerstown, MD. J. Lowinson, P. Ruiz, R. Millman, J. Langrod (Eds.).
48. Drucker E, Lurie P, Alcabes P, et al. Measuring harm reduction: the effects of needle and syringe exchange programs and methadone maintenance on the ecology of HIV. AIDS 1998, 12(Suppl A):S217-S230.
49. Stimson VG The global diffusion of injecting drug use: implications for human immunodeficiency virus infection. Bull Narcotics 1993, 45:3-17.
50. Des Jarlais DC, Friedman SR, Choopanya K, et al. International epidemiology of HIV and AIDS among injecting drug users. AIDS 1992, 6:1053-1068.
51. Garfein RS, Vlahov D, Galai N, et al. Viral infections in short-term injection drug users: the prevalence of the hepatitis C, hepatitis B, human immunodeficiency and human T-lymphotropic viruses. Am J Publ Health 1996, 85:655-661.
52. van Beek I, Dwyer R, Dore GJ, et al. Infection with HIV and hepatitis C virus among injecting drug users in a prevention setting: retrospective cohort study. Br Med J 1998, 317:433-437.
53. Heimer R, Myers SS, Cadman EC, et al. Detection by polymerase chain reaction of Human Immunodeficiency Virus type 1 proviral DNA sequences in needles of injecting drug users. J Infect Dis 1992, 165:781-782.
54. Guydish J, Clark G, Garcia D, et al. Detecting HIV antibodies in needle exchange syringes. VIIth International Conference on AIDS, Florence: 1991.
55. Clatts MC, Heimer R, Abdala N, et al. Illicit drug injection and HIV-1 transmission: heating drug solutions may inactive HIV-1. J Aquir Immune Defic Syndr 1999, 22:194-199.
56. Ciccarone D, Bourgois P Explaining the geographical variation of HIV among injection drug users in the United States. Subst Use Misuse 2003, 38:2049-2063.
57. Kral AH, Bluthenthal RN, Booth RE, et al. HIV seroprevalence among street-recruited injection drug and crack cocaine users in 16 US municipalities. Am J Publ Health 1998, 88:108-113.
58. Beckerleg S, Telfer M, Hundt GL The rise of injecting drug use in East Africa: A case study from Kenya. Harm Reduct J 2005, 212.
59. Aceijas C, Stimson GV, Hickman M, Rhodes T Global overview of injecting drug use and HIV infection among injecting drug users. United Nations Reference Group on HIV/AIDS Prevention and Care among IDU in Developing and Transitional Countries. AIDS 2004, 18(17):2295-2303.
60. Des Jarlais DC, Hagan H, Friedman S HIV Infection and AIDS: Epidemiology and emerging public health perspectives. Substance abuse: a comprehensive textbook 2004, Lippincott Williams and Wilkins, Hagerstown, MD. J. Lowinson, P. Ruiz, R. Millman, J. Langrod (Eds.).
61. Acquired Immunodeficiency Syndrome (AIDS): data at 31 December 1989. Wkly Epid Rec 1990, 65:1-2. Anon.
62. Acquired Immunodeficiency Syndrome: Romania. Wkly Epid Rec 1990, 65:56-57. Anon.
63. Situation de la region Europeene de I'OMS au 31 mars 1990 et analyse des cas transfusionnels au 31 decembre 1989. Rel Epidemiol Hebd 1990, 65:239-242. SIDA.
64. Hersh BS, Popovici F, Apetrei RC, et al. Acquired immunodeficiency syndrome in Romania. Lancet 1991, 338:645-649.
65. Hersh BS, Popovici F, Zolotusca L, et al. The epidemiology of HIV and AIDS in Romania. AIDS 1991, 5(Suppl 2):S87-S92.
66. Anon. AIDS surveillance in Europe. Paris: European Centre for the Epidemiological Monitoring of AIDS; 1995.
67. Apetrei C, Buzdugan I, Mitroi I, et al. Nosocomial HIV-1 transmission and primary prevention in Romania. Lancet 1994, 344:1028-1029.
68. Zaknun D, DiFranco M, Oswald HP, et al. Association between neopterin and beta-2-microglobulin levels and HIV status in Romanian orphanage children. Wien Klin Wochenschr 1993, 105:284-288.
69. Patrascu IV, Dumitrescu O The epidemic of human immunodeficiency virus infection in Romanian children. AIDS Res Hum Retroviruses 1993, 9:99-104.
70. Rudin C, Berger R, Tobler R, et al. HIV-1, hepatitis (A, B, and C), and measles in Romanian children. Lancet 1990, 336:1592-1593.
71. Di Franco MJ, Zaknun D, Zaknun J, et al. A prospective study of the association of serum neopterin, beta 2-microglobulin, and hepatitis B surface antigenemia with death in infants and children with HIV-1 disease. J Acquir Immune Defic Syndr 1994, 7:1079-1085.
72. Hersh BS, Popovici F, Jezek Z, et al. Risk factors for HIV infection among abandoned Romanian children. AIDS 1993, 7:1617-1624.
73. Patrascu IV, Constantinescu SN, Dublanchet A HIV-1 infection in Romanian children. Lancet 1990, 335:672.
74. Scarlatti G Mother-to-child transmission of HIV-1: advances and controversies of the twentieth centuries. AIDS Rev 2004, 6:67-78.
75. Mofenson LM Advances in the prevention of vertical transmission of human immunodeficiency virus. Semin Pediatr Infect Dis 2003, 14:295-308.
76. Rousseau CM, Nduati RW, Richardson BA, et al. Association of levels of HIV-1-infected breast milk cells and risk of mother-to-child transmission. J Infect Dis 2004, 190:1880-1888.
77. Apetrei RC Children with AIDS. World Health Forum 1990, 11:199.
78. Berkley S Parenteral transmission of HIV in Africa. AIDS 1991, 5(Suppl 1):S87-S92.
79. Werner BG, Grady GF Accidental hepatitis-B-surface-antigen-positive inoculations. Use of e antigen to estimate infectivity. Ann Intern Med 1982, 97:367-369.
80. Seeff LB, Wright EC, Zimmerman HJ, et al. Type B hepatitis after needle-stick exposure: prevention with hepatitis B immune globulin. Final report of the Veterans Administration Cooperative Study. Ann Intern Med 1978, 88:285-293.
81. Apetrei C, Descamps D, Panzaru C, et al. Plasma HIV-1 load and nosocomial transmission in Romanian children. AIDS 1995, 9:977.
82. Dumitrescu O, Kalish ML, Kliks SC, et al. Characterization of human immunodeficiency virus type 1 isolates from children in Romania: identification of a new envelope subtype. J Infect Dis 1994, 169:281-288.
83. Holm-Hansen C, Grothues D, Rustad S, et al. Characterization of HIV type 1 from Romanian children: lack of correlation between V3 loop amino acid sequence and syncytium formation in MT-2 cells. AIDS Res Hum Retroviruses 1995, 11:597-603.
84. Apetrei C, Loussert-Ajaka I, Collin G, et al. HIV type 1 subtype F sequences in Romanian children and adults. AIDS Res Hum Retroviruses 1997, 13:363-365.
85. Bandea CI, Ramos A, Pieniazek D, et al. Epidemiologic and evolutionary relationships between Romanian and Brazilian HIV-subtype F strains. Emerg Infect Dis 1995, 1:91-93.
86. Peeters M, Sharp PM Genetic diversity of HIV-1: the moving target. AIDS 2000, 14(Suppl 3):S129-S140.
87. McCutchan FE Understanding the genetic diversity of HIV-1. AIDS 2000, 14(Suppl 3):S31-S44.
88. Triques K, Bourgeois A, Saragosti S, et al. High diversity of HIV-1 subtype F strains in Central Africa. Virology 1999, 259:99-109.
89. Apetrei C, Descamps D, Collin G, et al. HIV type 1 diversity in northeastern Romania in 200-2001 based on phylogenic analysis of pol sequences from patient failing antiretroviral therapy. AIDS Res Hum Retroviruses 2003, 19:1155-1161.
90. Reinis M, Bruckova M, Graham RR, et al. Genetic subtypes of HIV type 1 viruses circulating in the Czech Republic. AIDS Res Hum Retroviruses 2001, 17:1305-1310.
91. Apetrei C, Necula A, Holm-Hansen C, et al. HIV-1 diversity in Romania. AIDS 1998, 12:1079-1085.
92. Pokrovskii W, Eramova I, Deulina MO, et al. [An intrahospital outbreak of HIV infection in Elista]. Zh Mikrobiol Epidemiol Immunobiol 1990; April, 17-23.
93. Bobkov A, Cheingsong-Popov R, Garaev M, et al. Identification of an env G subtype and heterogeneity of HIV-1 strains in the Russian Federation and Belarus. AIDS 1994, 8:1649-1655.
94. Bobkov A, Cheingsong-Popov R, Karasyova N, et al. Sequence analysis of the glycoprotein 120 coding region of a new human immunodeficiency virus type 1 subtype G strain from Russia. AIDS Res Hum Retroviruses 1996, 12:1385-1388.
95. Pokrovskii W, Eramov I, Kuznetsova II, et al. [HIV transmission from child to mother during breast feeding]. Zh Mikrobiol Epidemiol Immunobiol 1990; March, 23-26.
96. Bobkov A, Cheingsong-Popov R, Selimova L, et al. Genetic heterogeneity of HIV type 1 in Russia: identification of H variants and relationship with epidemiological data. AIDS Res Hum Retroviruses 1996, 12:1687-1690.
97. Bobkov A, Cheingsong-Popov R, Selimova L, et al. An HIV type 1 epidemic among injecting drug users in the former Soviet Union caused by a homogeneous subtype A strain. AIDS Res Hum Retroviruses 1997, 13:1195-1201.
98. Bobkov A, Cheingsong-Popov R, Selimova L, et al. HIV type 1 subtype E in Russia. AIDS Res Hum Retroviruses 1997, 13:725-727.
99. Bobkov A, Kazennova E, Selimova L, et al. A sudden epidemic of HIV type 1 among injecting drug users in the former Soviet Union: identification of subtype A, subtype B, and novel gagA/envB recombinants. AIDS Res Hum Retroviruses 1998, 14:669-676.
100. Bobkov A, Kazennova E, Selimova L, et al. HIV type 1 gag D/env G recombinants in Russia. AIDS Res Hum Retroviruses 1998, 14:1597-1599.
101. Bobkov A, Kazennova E, Khanina T, et al. An HIV type 1 subtype A strain of low genetic diversity continues to spread among injecting drug users in Russia: study of the new local outbreaks in Moscow and Irkutsk. AIDS Res Hum Retroviruses 2001, 17:257-261.
102. Liitsola K, Holm K, Bobkov A, et al. An AB recombinant and its parental HIV type 1 strains in the area of the former Soviet Union: low requirements for sequence identity in recombination. UNAIDS Virus Isolation Network. AIDS Res Hum Retroviruses 2000, 16:1047-1053.
103. Yerly S, Quadri R, Negro F, et al. Nosocomial outbreak of multiple bloodborne viral infections. J Infect Dis 2001, 184:369-372.
104. Visco-Comandini U, Cappiello G, Liuzzi G, et al. Monophyletic HIV type 1 CRF02-AG in a nosocomial outbreak in Benghazi, Libya. AIDS Res Hum Retroviruses 2002, 18:727-732.
105. Huytin Y The safe injecting global network 2001, WHO, Geneva.
106. Arora NK. Almost 63 percent of Indian injections unsafe. Report of All India Institute of Medical Sciences: Reported by Agence France Presse, 2005: (01.24.05).
107. Singh J, Gupta S, Khare S, Bhatia R, Jain DC, Sokhey J. A severe and explosive outbreak of hepatitis B in a rural population in Sirsa district, Haryana, India: unnecessary therapeutic injections were a major risk factor. Epidemiology & Infection. 2000 Dec; 125(3): 693-699.
108. Singh J, Bhatia R, Patnaik SK, Khare S, Bora D, Jain DC, Sokhey J. Community studies on hepatitis B in Rajahmundry town of Andhra Pradesh, India, 1997-8: unnecessary therapeutic injections are major risk factor. Epidemiology & Infection. 2000 Oct; 125(2): 367-375.
109. WHO/UNICEF. Product information sheets: Global program for vaccine and immunization. Expanded program on immunization. Geneva: WHO; 1997.
110. Rhodes T. Special issue on HIV/AIDS and in Eastern Europe and USSR. Int J Drug Policy 2004; April.
111. Drucker E Witch-hunt. Harm Reduct J 2005, 2:3.
112. Drucker E Appendix: An open letter to the delegates of the 48th session of the UN Commission on Narcotic Drugs (CND). Harm Reduct J 2005, 2:3. Online. Available: www.harmreductionjournal.com/content/2/1/3.
113. Marx PA, Alcabes PG, Drucker E Serial human passage of simian immune virus by unsterile injecting and the emergence of epidemic HIV in Africa. Philos Trans R Soc Lond B Biol Sci 2001, 356:911-920.
114. The origins of HIV and the AIDS epidemic 2001, The Royal Society, London. R. Weiss (Ed.).
115. Marx PA, Apetrie C, Drucker E AIDS as a Zoonosis? Confusion over the origin of the virus and the origin of the epidemic. J Med Primatol 2004, 33:220-226.