Enantioselective michael addition to α,β-Unsaturated aldehydes: Combinatorial catalyst preparation and screening, reaction optimization and mechanistic studies

Chemistry - A European Journal

Volumn 16, Issue 1, 2010, Pages 95-99

  Fleischer, Ivana ^a   Pfaltz, Andreas ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Asymmetric catalysis; Conjugate addition; Highthroughput screening; Mass spectrometry; Organocatalysis

Indexed keywords

ASYMMETRIC CATALYSIS; BACK REACTION; CATALYST MOLECULE; CHEMICAL EQUATIONS; CHIRAL CATALYST; COMBINATORIAL CATALYST; CONJUGATE ADDITION; ELECTROPHILIC ACTIVATION; ENANTIOSELECTIVE MICHAEL ADDITION; HIGH-THROUGHPUT SCREENING; MECHANISTIC STUDIES; MICHAEL ADDITIONS; NONLINEAR EFFECT; ORGANOCATALYSIS; REACTION OPTIMIZATION; UNSATURATED ALDEHYDES;

ADDITION REACTIONS; ALDEHYDES; CATALYSTS; MASS SPECTROMETERS; MASS SPECTROMETRY; NONLINEAR EQUATIONS; RATE CONSTANTS; REACTION KINETICS;

CATALYSIS;

EID: 73949140284     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200902449     Document Type: Article

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