Interleukin-13 stimulation of the mediastinal B-cell lymphoma cell line Karpas-1106P induces a phenotype resembling the Hodgkin lymphoma cell line L1236

Experimental Hematology

Volumn 38, Issue 2, 2010, Pages 116-123

  Andersson, Erik ^a,b   Schain, Frida ^a   Sjöberg, Jan ^a   Björkholm, Magnus ^a   Claesson, Hans Erik ^b,c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Orexo AB   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; CALCIUM ION; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 14; INTERLEUKIN 14 RECEPTOR; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; LEUKOTRIENE RECEPTOR; PEPTIDOLEUKOTRIENE RECEPTOR; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; AUTOCRINE EFFECT; B CELL LYMPHOMA; CALCIUM TRANSPORT; CELL SIZE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; FLOW CYTOMETRY; HODGKIN DISEASE; HUMAN; HUMAN CELL; INFLAMMATION; LYMPHOMA CELL LINE; MULTINUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING;

ARACHIDONATE 15-LIPOXYGENASE; CALCIUM; CELL LINE, TUMOR; CELL NUCLEUS; CELL SIZE; CYTOKINES; HODGKIN DISEASE; HUMANS; INFLAMMATION; INTERLEUKIN-13; INTERLEUKIN-4; LEUKOTRIENES; LYMPHOMA, B-CELL; PHENOTYPE; RECEPTORS, LEUKOTRIENE;

EID: 73949136303     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2009.11.005     Document Type: Article

References (32)

1. Rosenwald A., Wright G., Leroy K., et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 198 (2003) 851-862
2. Savage K.J., Monti S., Kutok J.L., et al. The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. Blood 102 (2003) 3871-3879
3. Mani H., and Jaffe E.S. Hodgkin lymphoma: an update on its biology with new insights into classification. Clin Lymphoma Myeloma 9 (2009) 206-216
4. Traverse-Glehen A., Pittaluga S., Gaulard P., et al. Mediastinal gray zone lymphoma: the missing link between classic Hodgkin's lymphoma and mediastinal large B-cell lymphoma. Am J Surg Pathol 29 (2005) 1411-1421
5. Kuppers R. The biology of Hodgkin's lymphoma. Nat Rev Cancer 9 (2009) 15-27
6. Thomas R.K., Re D., Wolf J., and Diehl V. Part I: Hodgkin's lymphoma-molecular biology of Hodgkin and Reed-Sternberg cells. Lancet Oncol 5 (2004) 11-18
7. Eberle F.C., Mani H., and Jaffe E.S. Histopathology of Hodgkin's Lymphoma. Cancer J 15 (2009) 129-137
8. Rodriguez J., Gutierrez A., and Piris M. Primary mediastinal B-cell lymphoma: Treatment and therapeutic targets. Leuk Lymphoma 49 (2008) 1050-1061
9. Claesson H.-E., and Dahlen S.-E. Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs. J Intern Med 245 (1999) 205-227
10. Schain F., Tryselius Y., Sjoberg J., et al. Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma. Int J Cancer 123 (2008) 2285-2293
11. Schain F., Schain D., Mahshid Y., et al. Differential expression of cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in non-Hodgkin lymphomas. Clin Lymphoma Myeloma 8 (2008) 340-347
12. Claesson H.E. On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma. Prostaglandins Other Lipid Mediat 89 (2009) 120-125
13. Kuhn H., and O'Donnell V.B. Inflammation and immune regulation by 12/15-lipoxygenases. Prog Lipid Res 45 (2006) 334-356
14. Andersson E., Schain F., Svedling M., Claesson H.E., and Forsell P.K. Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity. Biochim Biophys Acta 1761 (2006) 1498-1505
15. Claesson H.E., Griffiths W.J., Brunnstrom A., et al. Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: Novel insight into the inflammatory features of classical Hodgkin lymphoma. FEBS J 275 (2008) 4222-4234
16. Feltenmark S., Gautam N., Brunnstrom A., et al. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proc Natl Acad Sci U S A 105 (2008) 680-685
17. Skinnider B.F., Kapp U., and Mak T.W. The role of interleukin 13 in classical Hodgkin lymphoma. Leuk Lymphoma 43 (2002) 1203-1210
18. LaPorte S.L., Juo Z.S., Vaclavikova J., et al. Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell 132 (2008) 259-272
19. Wolf J., Kapp U., Bohlen H., et al. Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells. Blood 87 (1996) 3418-3428
20. Poppema S., Kluiver J.L., Atayar C., et al. Report: workshop on mediastinal grey zone lymphoma. Eur J Haematol Suppl l (2005) 45-52
21. Skinnider B.F., Elia A.J., Gascoyne R.D., et al. Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood 99 (2002) 618-626
22. Skinnider B.F., Elia A.J., Gascoyne R.D., et al. Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood 97 (2001) 250-255
23. Guiter C., Dusanter-Fourt I., Copie-Bergman C., et al. Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma. Blood 104 (2004) 543-549
24. Tangye S.G., Ferguson A., Avery D.T., Ma C.S., and Hodgkin P.D. Isotype switching by human B cells is division-associated and regulated by cytokines. J Immunol 169 (2002) 4298-4306
25. Brinckmann R., Topp M., Zalan I., et al. Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4. Biochem J 318 Pt 1 (1996) 305-312
26. Brinckmann R., and Kuhn H. Regulation of 15-lipoxygenase expression by cytokines. Adv Exp Med Biol 400B (1997) 599-604
27. Conrad D.J., and Lu M. Regulation of human 12/15-lipoxygenase by Stat6-dependent transcription. Am J Respir Cell Mol Biol 22 (2000) 226-234
28. Thivierge M., Stankova J., and Rola-Pleszczynski M. IL-13 and IL-4 up-regulate cysteinyl leukotriene 1 receptor expression in human monocytes and macrophages. J Immunol 167 (2001) 2855-2860
29. Zhai Y., Zhong Z., Chen C.Y., et al. Coordinated changes in mRNA turnover, translation, and RNA processing bodies in bronchial epithelial cells following inflammatory stimulation. Mol Cell Biol 28 (2008) 7414-7426
30. Skinnider B.F., and Mak T.W. The role of cytokines in classical Hodgkin lymphoma. Blood 99 (2002) 4283-4297
31. Maggio E., van den Berg A., Diepstra A., et al. Chemokines, cytokines and their receptors in Hodgkin's lymphoma cell lines and tissues. Ann Oncol 13 Suppl 1 (2002) 52-56
32. Teruya-Feldstein J., Tosato G., and Jaffe E.S. The role of chemokines in Hodgkin's disease. Leuk Lymphoma 38 (2000) 363-371