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Volumn 95, Issue 1, 2010, Pages 163-167

Thymosin β4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma

Author keywords

Cellular proliferation; Multiple myeloma; Thymosin 4

Indexed keywords

THYMOSIN BETA4;

EID: 73949121958     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.006411     Document Type: Article
Times cited : (21)

References (26)
  • 1
    • 1842734249 scopus 로고    scopus 로고
    • Thymosins: Chemistry and biological properties in health and disease
    • Goldstein AL, Badamchian M. Thymosins: chemistry and biological properties in health and disease. Expert Opin Biol Ther. 2004;4(4):559-73.
    • (2004) Expert Opin Biol Ther , vol.4 , Issue.4 , pp. 559-573
    • Goldstein, A.L.1    Badamchian, M.2
  • 3
    • 20044372562 scopus 로고    scopus 로고
    • Roles of thymosins in cancers and other organ systems
    • Chen C, Li M, Yang H, Chai H, Fisher W, Yao Q. Roles of thymosins in cancers and other organ systems. World J Surg. 2005; 29(3):264-70.
    • (2005) World J Surg , vol.29 , Issue.3 , pp. 264-270
    • Chen, C.1    Li, M.2    Yang, H.3    Chai, H.4    Fisher, W.5    Yao, Q.6
  • 4
    • 42149142956 scopus 로고    scopus 로고
    • Unraveling the biology of multiple myeloma disease: Cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment
    • Caers J, Van Valckenborgh E, Menu E, Van Camp B, Vanderkerken K. Unraveling the biology of multiple myeloma disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment. Bull Cancer. 2008;95(3):301-13.
    • (2008) Bull Cancer , vol.95 , Issue.3 , pp. 301-313
    • Caers, J.1    Van Valckenborgh, E.2    Menu, E.3    Van Camp, B.4    Vanderkerken, K.5
  • 5
    • 0023582914 scopus 로고
    • Differential expression of the human thymosin-beta 4 gene in lymphocytes, macrophages, and granulocytes
    • Gondo H, Kudo J, White JW, Barr C, Selvanayagam P, Saunders GF. Differential expression of the human thymosin-beta 4 gene in lymphocytes, macrophages, and granulocytes. J Immunol. 1987;139(11): 3840-8.
    • (1987) J Immunol , vol.139 , Issue.11 , pp. 3840-3848
    • Gondo, H.1    Kudo, J.2    White, J.W.3    Barr, C.4    Selvanayagam, P.5    Saunders, G.F.6
  • 6
    • 0344858002 scopus 로고    scopus 로고
    • Role of thymosin beta4 in tumor metastasis and angiogenesis
    • Cha HJ, Jeong MJ, Kleinman HK. Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst. 2003;95 (22):1674-80.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.22 , pp. 1674-1680
    • Cha, H.J.1    Jeong, M.J.2    Kleinman, H.K.3
  • 8
    • 66549106493 scopus 로고    scopus 로고
    • The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor
    • Sprynski AC, Hose D, Caillot L, Reme T, Shaughnessy JD Jr, Barlogie B, et al. The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. Blood. 2009;113(19):4614-26.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4614-4626
    • Sprynski, A.C.1    Hose, D.2    Caillot, L.3    Reme, T.4    Shaughnessy Jr, J.D.5    Barlogie, B.6
  • 9
    • 66149107431 scopus 로고    scopus 로고
    • Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma
    • Hose D, Reme T, Meissner T, Moreaux J, Seckinger A, Lewis J, et al. Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma. Blood. 2009;113(18):4331-40.
    • (2009) Blood , vol.113 , Issue.18 , pp. 4331-4340
    • Hose, D.1    Reme, T.2    Meissner, T.3    Moreaux, J.4    Seckinger, A.5    Lewis, J.6
  • 10
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007;8(1):118-27.
    • (2007) Biostatistics , vol.8 , Issue.1 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 11
    • 0033020874 scopus 로고    scopus 로고
    • Multiple myeloma and related disorders. Lessons from an animal model
    • Radl J. Multiple myeloma and related disorders. Lessons from an animal model. Pathol Biol (Paris). 1999;47(2):109-14.
    • (1999) Pathol Biol (Paris) , vol.47 , Issue.2 , pp. 109-114
    • Radl, J.1
  • 12
    • 0027085782 scopus 로고
    • A model of multiple myeloma: Culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse
    • Manning LS, Berger JD, O'Donoghue HL, Sheridan GN, Claringbold PG, Turner JH. A model of multiple myeloma: culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse. Br J Cancer. 1992;66(6):1088-93.
    • (1992) Br J Cancer , vol.66 , Issue.6 , pp. 1088-1093
    • Manning, L.S.1    Berger, J.D.2    O'Donoghue, H.L.3    Sheridan, G.N.4    Claringbold, P.G.5    Turner, J.H.6
  • 14
    • 0842321785 scopus 로고    scopus 로고
    • Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses
    • Breckpot K, Heirman C, De Greef C, van der Bruggen P, Thielemans K. Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses. J Immunol. 2004;172(4):2232-7.
    • (2004) J Immunol , vol.172 , Issue.4 , pp. 2232-2237
    • Breckpot, K.1    Heirman, C.2    De Greef, C.3    van der Bruggen, P.4    Thielemans, K.5
  • 15
    • 44949219133 scopus 로고    scopus 로고
    • Antitumour and antiangiogenic effects of Aplidin in the 5TMM syngeneic models of multiple myeloma
    • Caers J, Menu E, De Raeve H, Lepage D, Van Valckenborgh E, Van Camp B, et al. Antitumour and antiangiogenic effects of Aplidin in the 5TMM syngeneic models of multiple myeloma. Br J Cancer. 2008;98 (12):1966-74.
    • (2008) Br J Cancer , vol.98 , Issue.12 , pp. 1966-1974
    • Caers, J.1    Menu, E.2    De Raeve, H.3    Lepage, D.4    Van Valckenborgh, E.5    Van Camp, B.6
  • 16
    • 31544477115 scopus 로고    scopus 로고
    • Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts
    • Nummela P, Yin M, Kielosto M, Leaner V, Birrer MJ, Holtta E. Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts. Cancer Res. 2006;66(2):701-12.
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 701-712
    • Nummela, P.1    Yin, M.2    Kielosto, M.3    Leaner, V.4    Birrer, M.J.5    Holtta, E.6
  • 17
    • 0344668604 scopus 로고    scopus 로고
    • Thymosin beta4: A new molecular target for antitumor strategies
    • Goldstein AL. Thymosin beta4: a new molecular target for antitumor strategies. J Natl Cancer Inst. 2003;95(22):1646-7.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.22 , pp. 1646-1647
    • Goldstein, A.L.1
  • 18
    • 4444295381 scopus 로고    scopus 로고
    • Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma
    • Wang WS, Chen PM, Hsiao HL, Wang HS, Liang WY, Su Y. Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma. Oncogene. 2004;23(39):6666-71.
    • (2004) Oncogene , vol.23 , Issue.39 , pp. 6666-6671
    • Wang, W.S.1    Chen, P.M.2    Hsiao, H.L.3    Wang, H.S.4    Liang, W.Y.5    Su, Y.6
  • 19
    • 0037607199 scopus 로고    scopus 로고
    • Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells
    • Wang WS, Chen PM, Hsiao HL, Ju SY, Su Y. Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells. Oncogene. 2003;22(21):3297-306.
    • (2003) Oncogene , vol.22 , Issue.21 , pp. 3297-3306
    • Wang, W.S.1    Chen, P.M.2    Hsiao, H.L.3    Ju, S.Y.4    Su, Y.5
  • 20
    • 0024989554 scopus 로고
    • Expression of the thymosin beta 4 gene during differentiation of hematopoietic cells
    • Shimamura R, Kudo J, Kondo H, Dohmen K, Gondo H, Okamura S, et al. Expression of the thymosin beta 4 gene during differentiation of hematopoietic cells. Blood. 1990;76(5):977-84.
    • (1990) Blood , vol.76 , Issue.5 , pp. 977-984
    • Shimamura, R.1    Kudo, J.2    Kondo, H.3    Dohmen, K.4    Gondo, H.5    Okamura, S.6
  • 21
    • 19444385803 scopus 로고    scopus 로고
    • Presence of a peptide component of thymosin fraction-5 manifesting discrete cytostatic properties in HL-60 human promyelocytic leukemia cells
    • Spangelo BL, Pompilius M, Farrimond DD, Stevens N, Nieva R, Shroff S, et al. Presence of a peptide component of thymosin fraction-5 manifesting discrete cytostatic properties in HL-60 human promyelocytic leukemia cells. Int Immunopharmacol. 2005;5(7-8):1317-29.
    • (2005) Int Immunopharmacol , vol.5 , Issue.7-8 , pp. 1317-1329
    • Spangelo, B.L.1    Pompilius, M.2    Farrimond, D.D.3    Stevens, N.4    Nieva, R.5    Shroff, S.6
  • 23
    • 38149091473 scopus 로고    scopus 로고
    • Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells
    • Leeanansaksiri W, DeSimone SK, Huff T, Hannappel E, Huff TF. Thymosin beta 4 and its N-terminal tetrapeptide, AcSDKP, inhibit proliferation, and induce dysplastic, non-apoptotic nuclei and degranulation of mast cells. Chem Biodivers. 2004;1(7):1091-100.
    • (2004) Chem Biodivers , vol.1 , Issue.7 , pp. 1091-1100
    • Leeanansaksiri, W.1    DeSimone, S.K.2    Huff, T.3    Hannappel, E.4    Huff, T.F.5
  • 24
    • 33744747605 scopus 로고    scopus 로고
    • Thymosin beta4 and AcSDKP inhibit the proliferation of HL-60 cells and induce their differentiation and apoptosis
    • Huang WQ, Wang BH, Wang QR. Thymosin beta4 and AcSDKP inhibit the proliferation of HL-60 cells and induce their differentiation and apoptosis. Cell Biol Int. 2006;30(6):514-20.
    • (2006) Cell Biol Int , vol.30 , Issue.6 , pp. 514-520
    • Huang, W.Q.1    Wang, B.H.2    Wang, Q.R.3
  • 26
    • 50349084887 scopus 로고    scopus 로고
    • Actin and microtubules: Working together to control spindle polarity
    • Xu FL, Saunders WS. Actin and microtubules: working together to control spindle polarity. Cancer Cell. 2008;14(3):197-9.
    • (2008) Cancer Cell , vol.14 , Issue.3 , pp. 197-199
    • Xu, F.L.1    Saunders, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.