Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 21, 2009, Pages 7606-7614

  Martini, Elisabetta ^a   Salvicchi, Alberto ^a   Ghelardini, Carla ^a   Manetti, Dina ^a   Dei, Silvia ^a   Guandalini, Luca ^a   Martelli, Cecilia ^a   Melchiorre, Michele ^a   Cellai, Cristina ^a   Scapecchi, Serena ^a   Teodori, Elisabetta ^a   Romanelli, Maria Novella ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cognition enhancers; Mouse passive avoidance test; Sapuninfiram; Sunifiram

Indexed keywords

1 (4 BENZOYL[1,4]DIAZEPAN 1 YL)ETHANONE; 1 (4 BENZOYL[1,4]DIAZEPAN 1 YL)PROPAN 1 ONE; 1 (4 FLUORO BENZENESULFONYL)PIPERIDINE 4 CARBOXYLIC ACID METHYLAMIDE; 1 [4 (4 FLUOROBENZENESULFONYL) [1,4]DIAZEPAN 1 YL]ETHANONE; 1 [4 (4 FLUOROBENZENESULFONYL) [1,4]DIAZEPAN 1 YL]PROPAN 1 ONE; 1 [4 (PROPANE 2 SULFONYL) [1,4]DIAZEPAN 1 YL]ETHANONE; 1 [4 ACETYL(1,4)DIAZEPAN 1 YL] 2 PHENYLETHANONE; NOOTROPIC AGENT; PIRACETAM; SAPUNIFIRAM; SUNIFIRAM; UNCLASSIFIED DRUG; DM 235; PIPERAZINE DERIVATIVE; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; ANIMAL; CHEMISTRY; COGNITION; DISEASE MODEL; DRUG EFFECT; SYNTHESIS;

ANIMALS; COGNITION; DISEASE MODELS, ANIMAL; DRUG DESIGN; MICE; NOOTROPIC AGENTS; PIPERAZINES; SULFONAMIDES;

EID: 73949102429     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.08.055     Document Type: Article

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