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Volumn 50, Issue 3, 2009, Pages 285-294

Gly482Ser polymorphism of the coactivator-1α of the activated receptor of peroxisome γ proliferation in individuals from Maracaibo, Venezuela;Polimorfismo Gly482Ser del gen coactivador-1α del receptor activado de proliferación de los peroxisomas γ en individuos de la ciudad de Maracaibo, estado Zulia, Venezuela. Estudio preliminar

Author keywords

Insulin resistance; PGC 1; Polymorphism Gly482Ser

Indexed keywords

GLUCOSE; GLYCINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; SERINE; TRIACYLGLYCEROL; CHOLESTEROL; HEAT SHOCK PROTEIN; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 73949102079     PISSN: 05355133     EISSN: 05355133     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (33)
  • 1
    • 84871698063 scopus 로고    scopus 로고
    • Resistencia a la Insulina. Disponible en
    • American Heart Association, 2007. Resistencia a la Insulina. Disponible en www.americanheart.org
    • American Heart Association, 2007
  • 3
    • 0037069149 scopus 로고    scopus 로고
    • Resistencia a la insulina y su implicación en múltiples factores de riego asociados a diabetes tipo 2.
    • Sociedad Española de Diabetes
    • Sociedad Española de Diabetes. Resistencia a la insulina y su implicación en múltiples factores de riego asociados a diabetes tipo 2. Med Clín 2002; 119:458-463.
    • (2002) Med Clín , vol.119 , pp. 458-463
  • 4
    • 30444457098 scopus 로고    scopus 로고
    • The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects
    • Fanelli M, Filippi E, Sentinelli F, Romeo S, Fallarino M, Buzzetti R, Leonetti F, Baroni MG. The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects. Dis Markers 2005; 21:175-180.
    • (2005) Dis Markers , vol.21 , pp. 175-180
    • Fanelli, M.1    Filippi, E.2    Sentinelli, F.3    Romeo, S.4    Fallarino, M.5    Buzzetti, R.6    Leonetti, F.7    Baroni, M.G.8
  • 6
    • 74049155305 scopus 로고    scopus 로고
    • Cruz M, García M, López E, Valladares A, Sánchez R, Wacher N, Aguilar Gaytán, Kumare J. Genes candidatos como posibles marcadores de susceptibilidad a diabetes tipo 2. REB 2005; 24:81-86.
    • Cruz M, García M, López E, Valladares A, Sánchez R, Wacher N, Aguilar Gaytán, Kumare J. Genes candidatos como posibles marcadores de susceptibilidad a diabetes tipo 2. REB 2005; 24:81-86.
  • 7
    • 9144251642 scopus 로고    scopus 로고
    • A Gly482Ser polymorphism of the peroxisome proliferator activated receptor γ coactivator -1 (PGC-1) gene is associated with type 2 diabetes in caucasians
    • Kunej T, Globocnik P, Dovc P, Peterlin B, Petrovic D. A Gly482Ser polymorphism of the peroxisome proliferator activated receptor γ coactivator -1 (PGC-1) gene is associated with type 2 diabetes in caucasians. Folia Biol (Praha) 2004; 50:157-158.
    • (2004) Folia Biol (Praha) , vol.50 , pp. 157-158
    • Kunej, T.1    Globocnik, P.2    Dovc, P.3    Peterlin, B.4    Petrovic, D.5
  • 8
    • 26244458017 scopus 로고    scopus 로고
    • Effects of the peroxisome proliferator-activated receptor gamma coactivator - 1 Gly482Ser variant on features of the metabolic syndrome
    • Vohl M, Houde A, Lebel S, Hould FS, Marceau P. Effects of the peroxisome proliferator-activated receptor gamma coactivator - 1 Gly482Ser variant on features of the metabolic syndrome, Mol Genet Metab. 2005; 86: 600-606.
    • (2005) Mol Genet Metab , vol.86 , pp. 600-606
    • Vohl, M.1    Houde, A.2    Lebel, S.3    Hould, F.S.4    Marceau, P.5
  • 9
    • 33845770418 scopus 로고    scopus 로고
    • Nitz I, Ewert A, Klapper M. Dormy T. Analysis of PGC-1 alfa variant Gly482Ser and Thr612Met concerning their PPARs function. Biochem Biophys Res Commun 2007; 353:481-486.
    • Nitz I, Ewert A, Klapper M. Dormy T. Analysis of PGC-1 alfa variant Gly482Ser and Thr612Met concerning their PPARs function. Biochem Biophys Res Commun 2007; 353:481-486.
  • 10
    • 0037340930 scopus 로고    scopus 로고
    • A Gly482Ser missense mutation in the peroxisome proliferator activated receptor γ coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians
    • Muller L, Bogardus C, Pedersen O, Baier L. A Gly482Ser missense mutation in the peroxisome proliferator activated receptor γ coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 2003; 52:895-898.
    • (2003) Diabetes , vol.52 , pp. 895-898
    • Muller, L.1    Bogardus, C.2    Pedersen, O.3    Baier, L.4
  • 13
    • 11844283357 scopus 로고    scopus 로고
    • Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) gene in Danish subjects with the metabolic syndrome
    • Ambye L, Rasmussen S, Fenger M, Jorgensen T, Borch-Johhsen K, Madsbad S, Urhammer S. Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) gene in Danish subjects with the metabolic syndrome. Diabetes Res Clin Pract 2004; 67:175-179.
    • (2004) Diabetes Res Clin Pract , vol.67 , pp. 175-179
    • Ambye, L.1    Rasmussen, S.2    Fenger, M.3    Jorgensen, T.4    Borch-Johhsen, K.5    Madsbad, S.6    Urhammer, S.7
  • 15
    • 42449113349 scopus 로고    scopus 로고
    • PPARGC1A (PGC1A) Variation associated with DNA damage, diabetes and cardiovascular diseases: The Boston Puerto Rican Health Study
    • Lai C, Tucker K, Parnell L, Adiconis X, Garcia-Bailo B, Griffith J, Meydani M, Ordovas J. PPARGC1A (PGC1A) Variation associated with DNA damage, diabetes and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes 2008; 57: 809-816.
    • (2008) Diabetes , vol.57 , pp. 809-816
    • Lai, C.1    Tucker, K.2    Parnell, L.3    Adiconis, X.4    Garcia-Bailo, B.5    Griffith, J.6    Meydani, M.7    Ordovas, J.8
  • 16
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell funtion from fasting plasma glucose and insulin concentrations in man
    • Matthews D, Hosker J, Rudenski A, Naylor B, Treacher D, Turner R. Homeostasis model assessment: Insulin resistance and beta-cell funtion from fasting plasma glucose and insulin concentrations in man. Diabetología 1985; 28:412-419.
    • (1985) Diabetología , vol.28 , pp. 412-419
    • Matthews, D.1    Hosker, J.2    Rudenski, A.3    Naylor, B.4    Treacher, D.5    Turner, R.6
  • 18
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald W, Levy R, Fredrickson D. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.1    Levy, R.2    Fredrickson, D.3
  • 20
    • 0024284028 scopus 로고
    • A simple satting out procedure for extracting from human nucleated cells
    • Miller A, Oykes D, Polesky H. A simple satting out procedure for extracting from human nucleated cells. Nucleic Acids Res 1988; 16:12-15.
    • (1988) Nucleic Acids Res , vol.16 , pp. 12-15
    • Miller, A.1    Oykes, D.2    Polesky, H.3
  • 21
    • 74049096623 scopus 로고    scopus 로고
    • preventing and managing the global epidemic of obesity. R word consultation of obesity. Geneva 3-5 june
    • World Heart Organization Obesity: preventing and managing the global epidemic of obesity. R word consultation of obesity. Geneva 3-5 june 1997.
    • (1997) World Heart Organization Obesity
  • 23
    • 2542434277 scopus 로고    scopus 로고
    • Thamer O Tschriter T, Van Haeftens S, Jacob J, Dekker J, Maassen F, Schick R, Heine H, Haring T. The Gly482ser variant in the peroxisome proliferator- activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non diabetic German and Dutch population
    • Stumvoll M, Fritsche A, t'Hart L, Machann C, Thamer O Tschriter T, Van Haeftens S, Jacob J, Dekker J, Maassen F, Schick R, Heine H, Haring T. The Gly482ser variant in the peroxisome proliferator- activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non diabetic German and Dutch population. Exp Clin Endocrinol Diabetes 2004; 112:253-257.
    • (2004) Exp Clin Endocrinol Diabetes , vol.112 , pp. 253-257
    • Stumvoll, M.1    Fritsche, A.2    t'Hart, L.3    Machann, C.4
  • 24
    • 0036094896 scopus 로고    scopus 로고
    • No association between the G482S polymorphism of the proliferator activated receptor- gamma coactivator-1 (PGC1) gene and type II diabetes in french
    • Lacquemant M, Chikri P, Boutin C, Samson P, Froguel P. No association between the G482S polymorphism of the proliferator activated receptor- gamma coactivator-1 (PGC1) gene and type II diabetes in french Caucasias. Diabetologia.2002; 45:602-603.
    • (2002) Caucasias. Diabetologia , vol.45 , pp. 602-603
    • Lacquemant, M.1    Chikri, P.2    Boutin, C.3    Samson, P.4    Froguel, P.5
  • 25
    • 0035985096 scopus 로고    scopus 로고
    • A genetic variation in the PGC1 gene could confer insulin resistance and suceptibility to type II diabetes
    • Hara K, Tobe K, Okada T, Kadowaki H, Akanuma Y, Ito C, Kimura S, Kawaoki T. A genetic variation in the PGC1 gene could confer insulin resistance and suceptibility to type II diabetes. Diabetología 2002; 45:740-743.
    • (2002) Diabetología , vol.45 , pp. 740-743
    • Hara, K.1    Tobe, K.2    Okada, T.3    Kadowaki, H.4    Akanuma, Y.5    Ito, C.6    Kimura, S.7    Kawaoki, T.8
  • 26
    • 34248589346 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma coactivator-1 alpha Gene (PGC-1) is not associated with Type 2 Diabetes Mellitus or body mass index among hispanic and non hispanic whites from colorado
    • Nelson T, Fingerlin T, Moss L, Barmada M, Ferrell R, Norris J. The peroxisome proliferator-activated receptor gamma coactivator-1 alpha Gene (PGC-1) is not associated with Type 2 Diabetes Mellitus or body mass index among hispanic and non hispanic whites from colorado. Exp Clin Endocrinol Diabetes 2007; 115:268-275.
    • (2007) Exp Clin Endocrinol Diabetes , vol.115 , pp. 268-275
    • Nelson, T.1    Fingerlin, T.2    Moss, L.3    Barmada, M.4    Ferrell, R.5    Norris, J.6
  • 27
    • 0035676129 scopus 로고    scopus 로고
    • Mutation analisys of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to type II diabetes mellitus
    • Ek J, Andersen G, Urhammer S, Gaede P, Drivsholm T, Borch-Johnsen K, Pedersen O. Mutation analisys of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to type II diabetes mellitus. Diabetologia 2001; 44: 2220-2226.
    • (2001) Diabetologia , vol.44 , pp. 2220-2226
    • Ek, J.1    Andersen, G.2    Urhammer, S.3    Gaede, P.4    Drivsholm, T.5    Borch-Johnsen, K.6    Pedersen, O.7
  • 28
    • 12944308811 scopus 로고    scopus 로고
    • Common polymorphism of the PPARgamma2 (pro12ala) and PGC-1 alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOPNIDDM trial
    • Andrulionyte L, Zacharova J, Chiasson Jl. Common polymorphism of the PPARgamma2 (pro12ala) and PGC-1 alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOPNIDDM trial. Diabetologia 2004; 47:2176-2184.
    • (2004) Diabetologia , vol.47 , pp. 2176-2184
    • Andrulionyte, L.1    Zacharova, J.2    Chiasson, J.3
  • 29
    • 21644444035 scopus 로고    scopus 로고
    • PPARGC1 genotype (Gly482Ser) predicts exceptional endurance capacity in European males
    • Lucia A, Gomez-Gallego F, Barroso I. PPARGC1 genotype (Gly482Ser) predicts exceptional endurance capacity in European males. J Appl Physiol 2005; 99:344-348.
    • (2005) J Appl Physiol , vol.99 , pp. 344-348
    • Lucia, A.1    Gomez-Gallego, F.2    Barroso, I.3
  • 30
    • 0037423717 scopus 로고    scopus 로고
    • Reduced expression of PGC-1 and insulin- signalling molecules in adipose tissue is associated with insulin resistance
    • Hammarstedt A, Jansson P, Wesslau X, Smith Y. Reduced expression of PGC-1 and insulin- signalling molecules in adipose tissue is associated with insulin resistance. Biochem Biophys Res Commun 2003; 301:578-583.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 578-583
    • Hammarstedt, A.1    Jansson, P.2    Wesslau, X.3    Smith, Y.4
  • 31
    • 0035909074 scopus 로고    scopus 로고
    • Hypertriglyceridemic hyperapoB: The unappreciated atherogenic dyslipoproteinemia in type 2 diabetes mellitus
    • Sniderma A, Scantlebury T, Cianflone K. Hypertriglyceridemic hyperapoB: the unappreciated atherogenic dyslipoproteinemia in type 2 diabetes mellitus. Ann Intern Med 2001; 135:447-459.
    • (2001) Ann Intern Med , vol.135 , pp. 447-459
    • Sniderma, A.1    Scantlebury, T.2    Cianflone, K.3
  • 32
    • 31144439939 scopus 로고    scopus 로고
    • Low-density lipoprotein size and cardiovascular risk assessment
    • Rizzo M, Berneis K. Low-density lipoprotein size and cardiovascular risk assessment. J Med 2006; 99:1-14.
    • (2006) J Med , vol.99 , pp. 1-14
    • Rizzo, M.1    Berneis, K.2
  • 33
    • 44649134173 scopus 로고    scopus 로고
    • Insulin sensitivity in type 2 diabetes is closely associated with LDL particle
    • Krayenbuehla P, Wieslib P, Schmidb C, Lehmannb R, Spinasb G. Insulin sensitivity in type 2 diabetes is closely associated with LDL particle. Swiss Med Wkly 2008; 138:275-280.
    • (2008) Swiss Med Wkly , vol.138 , pp. 275-280
    • Krayenbuehla, P.1    Wieslib, P.2    Schmidb, C.3    Lehmannb, R.4    Spinasb, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.