HIF-2α-haploinsufficient mice have blunted retinal neovascularization due to impaired expression of a proangiogenic gene battery

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 6, 2008, Pages 2714-2720

  Dioum, Elhadji M ^a   Clarke, Stephen L ^a   Ding, Kan ^a   Repa, Joyce J ^a   Garcia, Joseph A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OXYGEN; ANGIOGENIC PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HAPLOTYPE; HISTOPATHOLOGY; HYPOXIA; MOUSE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; RETINA; RETINA BLOOD VESSEL; RETINA NEOVASCULARIZATION; WILD TYPE; ANIMAL; ANOXIA; C57BL MOUSE; CULTURE TECHNIQUE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; MISSENSE MUTATION; PATHOLOGY; PHYSIOLOGY; PLASMID; REPORTER GENE; RETROLENTAL FIBROPLASIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOP CODON;

ANGIOGENIC PROTEINS; ANIMALS; ANIMALS, NEWBORN; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CULTURE TECHNIQUES; CODON, NONSENSE; FEMALE; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INFANT, NEWBORN; MALE; MICE; MICE, INBRED C57BL; MUTATION, MISSENSE; OXYGEN; PLASMIDS; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; RETINOPATHY OF PREMATURITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 47249111254     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1469     Document Type: Article

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