Induction of mitogen-activated protein kinases is proportional to the amount of pressure overload

Hypertension

Volumn 55, Issue 1, 2010, Pages 137-143

  Esposito, Giovanni ^a   Perrino, Cinzia ^a   Schiattarella, Gabriele Giacomo ^a   Belardo, Lorena ^a   Di Pietro, Elisa ^a   Franzone, Anna ^a   Capretti, Giuliana ^a   Gargiulo, Giuseppe ^a   Pironti, Gianluigi ^a   Cannavo, Alessandro ^a   Sannino, Anna ^a   Izzo, Raffaele ^a   Chiariello, Massimo ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cardiac hypertrophy; ERK; Hypertension; Leukocytes; MAPKs

Indexed keywords

ATRIAL NATRIURETIC FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE 1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HEART VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTOLIC BLOOD PRESSURE;

ANIMALS; AORTA; ATRIAL NATRIURETIC FACTOR; BLOOD PRESSURE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CONSTRICTION, PATHOLOGIC; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMANS; HYPERTENSION; HYPERTROPHY; LEUKOCYTES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRESSURE;

EID: 73849151773     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.135467     Document Type: Article

References (14)

1. Opie LH, Commerford PJ, Gersh BJ, Pfeffer MA. Controversies in ventricular remodelling. Lancet. 2006;367:356-367.
2. Perrino C, Rockman HA, Chiariello M. Targeted inhibition of phospho-inositide 3-kinase activity as a novel strategy to normalize beta-adrenergic receptor function in heart failure. Vascul Pharmacol. 2006; 45:77-85.
3. Esposito G, Prasad SV, Rapacciuolo A, Mao L, Koch WJ, Rockman HA. Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload. Circulation. 2001;103:1453-1458.
4. Chien KR, Zhu H, Knowlton KU, Miller-Hance W, van-Bilsen M, O'Brien TX, Evans SM. Transcriptional regulation during cardiac growth and development. Annu Rev Physiol. 1993;55:77-95. (Pubitemid 23102124)
5. Gardner DG, Deschepper CF, Ganong WF, Hane S, Fiddes J, Baxter JD, Lewicki J. Extra-atrial expression of the gene for atrial natriuretic factor. Proc Natl Acad Sci U S A. 1986;83:6697-6701.
6. Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. J Clin Invest. 2006;116:1547-1560.
7. Michel MC, Brodde OE, Insel PA. Peripheral adrenergic receptors in hypertension. Hypertension. 1990;16:107-120.
8. Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field LJ, Ross J Jr, Chien KR. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc Natl Acad Sci U S A. 1991;88: 8277-8281.
9. Dorn GW II, Hahn HS. Genetic factors in cardiac hypertrophy. Ann N Y Acad Sci. 2004;1015:225-237.
10. Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene. 2007;26: 3291-3310.
11. Clark JE, Sarafraz N, Marber MS. Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease. Pharmacol Ther. 2007;116: 192-206.
12. Esposito G, Rapacciuolo A, Naga Prasad SV, Rockman HA. Cardiac hypertrophy: role of G protein-coupled receptors. J Card Fail. 2002;8: S409-S414.
13. Tachibana H, Perrino C, Takaoka H, Davis RJ, Naga Prasad SV, Rockman HA. JNK1 is required to preserve cardiac function in the early response to pressure overload. Biochem Biophys Res Commun. 2006;343: 1060-1066.
14. Corbucci GG, Perrino C, Donato G, Ricchi A, Lettieri B, Troncone G, Indolfi C, Chiariello M, Avvedimento EV. Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion. J Am Coll Cardiol. 2004;43:1992-1999.