Mapping simocyclinone D8 interaction with DNA gyrase: Evidence for a new binding site on GyrB

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 1, 2010, Pages 213-220

  Sissi, C ^a   Vazquez, E ^a   Chemello, A ^a   Mitchenall, L A ^b   Maxwell, A ^b   Palumbo, M ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; ADPNP; ANTIBIOTIC AGENT; COUMARIN DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE (ATP HYDROLYSING) B; NOVOBIOCIN; SIMOCYCLINONE D8; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DRUG BINDING; DRUG INHIBITION; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME STABILITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN;

ANTI-BACTERIAL AGENTS; BINDING SITES; BINDING, COMPETITIVE; CIRCULAR DICHROISM; COUMARINS; DNA GYRASE; DNA, BACTERIAL; DNA, SUPERHELICAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GLYCOSIDES; THERMODYNAMICS;

EID: 73849150169     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00972-09     Document Type: Article

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