Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions

Journal of Molecular Biology

Volumn 311, Issue 1, 2001, Pages 195-203

  Sissi, Claudia ^a   Perdonà, Elisabetta ^b   Domenici, Enrico ^b   Feriani, Aldo ^b   Howells, Alison J ^c   Maxwell, Anthony ^c   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b GSK   (Italy)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Affinity chromatography; Circular dichroism; DNA gyrase A; Magnesium; Quinolone

Indexed keywords

ANTIINFECTIVE AGENT; CARBOXYLIC ACID DERIVATIVE; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); MAGNESIUM ION; METAL ION; PROTEIN SUBUNIT;

AFFINITY CHROMATOGRAPHY; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DRUG BINDING; DRUG PROTEIN BINDING; ENZYME BINDING; PRIORITY JOURNAL; PROTEIN FOLDING;

EID: 0035800671     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4838     Document Type: Article

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