The mitA gene of Aspergillus fumigatus is required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity

Fungal Genetics and Biology

Volumn 47, Issue 2, 2010, Pages 169-178

  Kotz, Andrea ^a   Wagener, Johannes ^a   Engel, Jakob ^b   Routier, Françoise ^b   Echtenacher, Bernd ^c   Pich, Andreas ^b   Rohde, Manfred ^d   Hoffmann, Petra ^c   Heesemann, Jürgen ^a   Ebel, Frank ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Aspergillus fumigatus; Germination; Glycosphingolipids; Innate immune response; Mannosylation; MIPC

Indexed keywords

CASPOFUNGIN; FUNGAL PROTEIN; GLYCOSPHINGOLIPID; GUANOSINE DIPHOSPHATE MANNOSE; INOSITOL PHOSPHORYLCERAMIDE; MANNOSE; MITA PROTEIN; POSACONAZOLE; UNCLASSIFIED DRUG; VORICONAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CELL WALL; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXTRACELLULAR CALCIUM; FUNGAL MORPHOLOGY; FUNGAL SPORE GERMINATION; FUNGAL VIRULENCE; FUNGUS GROWTH; HOST PATHOGEN INTERACTION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CALCIUM; CELL LINE; CELL WALL; CELLS, CULTURED; FUNGAL PROTEINS; GLYCOSPHINGOLIPIDS; HUMANS; IMMUNITY, INNATE; MACROPHAGES; MANNOSE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; SACCHAROMYCES CEREVISIAE;

EID: 73749088372     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2009.10.001     Document Type: Article

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