Image analysis of Ca2+ signals as a basis for neurotoxicity assays: Promises and challenges

Neurotoxicology and Teratology

Volumn 32, Issue 1, 2010, Pages 16-24

  Barhoumi, Rola ^a   Qian, Yongchang ^a   Burghardt, Robert C ^a   Tiffany Castiglioni, Evelyn ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Ca2+ modeling; Ca2+ oscillations; Ca2+ waves; Toxicity; Toxin exposure

Indexed keywords

BENZO[A]PYRENE; BENZO[E]PYRENE; CALCIUM ION; CHRYSENE; DIAZOXIDE; HORMONE; LEAD; MANGANESE; NEUROTRANSMITTER; PROPOFOL; VALPROIC ACID; CALCIUM;

ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ACTIVITY; CELL DIFFERENTIATION; CELL DIVISION; CELL FUNCTION; CELL METABOLISM; CYTOLOGY; CYTOSOL; HIGH THROUGHPUT SCREENING; HORMONE RELEASE; HUMAN; IMAGE ANALYSIS; IN VITRO STUDY; INDIVIDUALIZATION; METHODOLOGY; MOLECULAR MECHANICS; MUSCLE CONTRACTION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SIGNAL TRANSDUCTION; STEADY STATE; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; METABOLISM; MOLECULAR IMAGING; REVIEW; TOXICITY AND INTOXICATION; TOXICITY TESTING;

ANIMALS; ASTROCYTES; CALCIUM; CALCIUM SIGNALING; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR IMAGING; NEUROTOXICITY SYNDROMES; TOXICITY TESTS;

EID: 73649146605     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2009.06.002     Document Type: Article

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