Pesticides may be altering constitutive nitric oxide release, thereby compromising health

Medical Science Monitor

Volumn 12, Issue 10, 2006, Pages

  Casares, Federico M ^b   Mantione, Kirk J ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Basal NO levels; Calcium; Constitutive nitric oxide synthase; Environmental pollutants; Immune system; Lobster; Nervous system; Nitric oxide; Organochlorines; Organophosphates; Pesticides; Pyrethroids

Indexed keywords

ION; NITRIC OXIDE; ORGANOPHOSPHATE; ORGANOPHOSPHATE PESTICIDE; PESTICIDE; PYRETHROID;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CONTROLLED STUDY; HOMEOSTASIS; IMMUNE RESPONSE; NERVE CELL; NONHUMAN; POLLUTANT;

ANIMALS; CALCIUM; ENVIRONMENTAL POLLUTANTS; HEALTH; HYDROCARBONS, CHLORINATED; IMMUNE SYSTEM; MODELS, BIOLOGICAL; NERVOUS SYSTEM PHYSIOLOGICAL PHENOMENA; NERVOUS SYSTEM PHYSIOLOGY; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PESTICIDES; PHOSPHORIC ACID ESTERS; PYRETHRINS;

EID: 33749677659     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (82)

1. Russell S, Hobbie K, Burrage T et al: Identification of a protozoan parasite in the American lobster Homarus americanus. J Shellfish Res, 2000; 19: 581
2. Long Island Sound Lobster Research Initiative. 2004
3. Pearce J, Balcom N: The 1999 Long Island Sound lobster mortality event: Findings of the comprehensive research initiative. J Shellfish Res, 2005; 24: 691-97
4. Cuomo C, Valente R, Dogru D: Seasonal variations in sediment and bottom water chemistry of western Long Island Sound: Implication for lobster mortality. J Shellfish Res, 2005; 24: 805-14
5. Mullen T, Russell S, Tucker M et al: Paramoebiasis associated mass mortality of American lobster (Homarus americanus) in Long Island Sound. J Aquat Anim Health, 2004; 16: 29-38
6. Zulkosky A, Ruggieri J, Terracciano S et al: Acute toxicity of resmethrin, malathion and methoprene to larval and juvenile american lobsters (Homarus americanus) and analysis of pesticide levels in surface waters after Scourge, Anvil and Altosid application. J Shellfish Res, 2005; 24: 795-804
7. Casares FM, McElroy A, Mantione KJ et al: The American lobster, Homarus americanus, contains morphine that is coupled to nitric oxide release in its nervous and immune tissues: Evidence for neurotransmitter and hormonal signaling. Neuroendocrinology Letters, 2005; 26: 89-97
8. ATSDR - Agency for Toxic Substances and Disease Registry. Toxicological Profiles, 2002
9. Cima F, Ballarin L: Tributyltin induces cytoskeletal alterations in the colonial ascidian Botryllus schlosseri phagocytes via interaction with calmodulin. Aquatic Toxicol, 2000; 48: 419-29
10. Andrews JE, Courtney KD, Donaldson WE: Impairment of calcium homeostasis by hexachlorobenzene (HCB) exposure in Fischer 344 rats. J Toxicol Environ Health, 1988; 23: 311-20
11. Andrews JE, Jackson LD, Stead AG, Donaldson WE: Morphometric analysis of osteosclerotic bone resulting from hexachlorobenzene exposure. J Toxicol Environ Health, 1990; 31: 193-201
12. Gomez-Mendikute A, Cajaraville MP: Comparative effects of cadmium, copper, paraquat and benzo[a]pyrene on the actin cytoskeleton and production of reactive oxygen species (ROS) in mussel haemocytes. Toxicol In Vitro, 2003; 17: 539-46
13. Grosman N, Diel F: Influence of pyrethroids and piperonyl butoxide on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. Int Immunopharmacol, 2005; 5: 263-70
14. Shafer TJ, Meyer DA: Effects of pyrethroids on voltage-sensitive calcium channels: a critical evaluation of strengths, weaknesses, data needs, and relationship to assessment of cumulative neurotoxicity. Toxicol Appl Pharmacol, 2004; 196: 303-18
15. Rao MR, Kanji VK, Sekhar V: Pesticide induced changes of nitric oxide synthase in rat brain in vitro. Drug Chem Toxicol, 1999; 22: 411-20
16. Pala I, Vig PJ, Desaiah D, Srinivasan A: In vitro effects of organophosphorus compounds on calmodulin activity. J Appl Toxicol, 1991; 11: 391-95
17. Liu PS, Kao LS, Lin MK: Organophosphates inhibit catecholamine secretion and calcium influx in bovine adrenal chromaffin cells. Toxicology, 1994; 90: 81-91
18. Stefano GB, Goumon Y, Bilfinger TV et al: Basal nitric oxide limits immune, nervous and cardiovascular excitation: Human endothelia express a mu opiate receptor. Progress in Neurobiology, 2000; 60: 531-44
19. Hose JE, Martin GG: Defense functions of granulocytes in the ridge-back prawn Sicyonia ingentis. J Invertebr Pathol, 1989; 53: 335-46
20. Johansson MW, Keyser P, Sritunyalucksana K, Soderhall K: Crustacean hemocytes and haematopoiesis. Aquaculture, 2000; 191: 45-52
21. Lee SY, Soderhall K: Early events in crustacean innate immunity. Fish Shellfish Immunol, 2002; 12: 421-37
22. Soderhall K: Invertebrate immunity. Dev Comp Immunol, 1999; 23: 263-66
23. Soderhall K, Cerenius L: Role of the prophenoloxidase-activating system in invertebrate immunity. Curr Opin Immunol, 1998; 10: 23-28
24. Chisholm JR, Smith VJ: Comparison of antibacterial activity in the hemocytes of different crustacean species. Comp Biochem Physiol A Physiol, 1995; 110: 39-45
25. Freire Marques MR, Barracco MA: Lectins, as non-self-recognition factors, in crustaceans. Aquaculture, 2000; 191: 23-44
26. Sritunyalucksana K, Soderhall K: The proPO and clotting system in crustaceans. Aquaculture, 2000; 191: 53-69
27. Clancy RM, Leszczynska-Piziak J, Abramson SB: Nitric Oxide stimulates the ADP-ribosylation of actin in human neutrophils. Biochem Biophys Res Commun, 1993; 191: 847-52
28. Jun CD, Han MK, Kim UH, Chung HT: Nitric oxide stimulates the ADPribosylation of actin in murine macrophages: association with the inhibition of pseudopodia formation, phagocytic activity, and adherence on a laminal substratum. Cell Immunol, 1996; 174: 25-31
29. Bachere E, Destoumieux D, Bulet P: Penaeidins, antimicrobial peptides of shrimp: A comparison with other effectors of innate immunity. Aquaculture, 2000; 191: 71-88
30. Destoumieux D, Bulet P, Loew D et al: Penaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda). J Biol Chem, 1997; 272: 28398-406
31. Stefano GB, Cadet P, Zhu W et al: The blueprint for stress can be found in invertebrates. Neuroendocrinology Letters, 2002; 23: 85-93
32. Croen KD: Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication. J Clin Invest, 1993; 91: 2446-52
33. Murad F: Nitric oxide signaling: would you believe that a simple free radical could be a second messenger, autacoid, paracrine substance, neurotransmitter, and hormone?. Recent Progress in Hormone Research, 1998; 53: 43-59
34. Torres J, Wilson MT: The reactions of copper proteins with nitric oxide. Biochim Biophys Acta, 1999; 1411: 310-22
35. Stefano GB: Autoimmunovascular regulation: Morphine and anandamide stimulated nitric oxide release. J Neuroimmunol, 1998; 83: 70-76
36. Gorren AC, de Boer E, Wever R: The reaction of nitric oxide with copper proteins and the photodissociation of copper-NO complexes. Biochim Biophys Acta, 1987; 916: 38-47
37. Nieto-Fernandez FE, Mattocks DW, Cavani F et al: Morphine coupling to invertebrate immunocyte nitric oxide release is dependent on intracellular calcium transients. Comp Biochem Physiol, 1999; 123: 295-99
38. Magazine HI, Chang J, Goumon Y, Stefano GB: Rebound from nitric oxide inhibition triggers enhanced monocyte activation and chemotaxis. J Immunol, 2000; 165: 102-7
39. Magazine HI, Liu Y, Bilfinger TV et al: Morphine-induced conformational changes in human monocytes,granulocytes, and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide. J Immunol, 1996; 156: 4845-50
40. Stefano GB, Benz D: Nitric oxide modulates cell shape. Current Opinions in European Medicine, 2002; 3: 32-39
41. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacological Reviews, 1991; 43: 109-42
42. Moncada S, Higgs A: The L-arginine-nitric oxide pathway. New Eng J Med, 1993; 329: 2002-12
43. Szabo C, Day BJ, Salzman AL: Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger. FEBS Letters, 1996; 381: 82-86
44. Stefano GB, Bilfinger TV: Human neutrophil and macrophage chemokinesis induced by cardiopulmonary bypass: Loss of DAME and IL-1 chemotaxis. J Neuroimmunol, 1993; 47: 189-98
45. Szabo C: Alterations in nitric oxide production in various forms of circulatory shock. New Horizons, 1995; 3: 2-32
46. Szabo C: Physiological and pathophysiological roles of nitric oxide in the central nervous system. Brain Res Bull, 1996; 41: 131-41
47. Pasternak GW: The Opiate Receptors. New Jersey: Humana Press, 1988
48. Stefano GB, Prevot V, Beauvillain JC et al: Acute exposure of estrogen to human endothelia results in nitric oxide release mediated by an estrogen surface receptor coupled to intracellular calcium transients. Circulation, 2000; 101: 1594-97
49. Takehara Y, Kanno T, Yoshioka T et al: Oxygen-dependent regulation of mitochondrial energy metabolism by nitric oxide. Archives of Biochemistry & Biophysics, 1995; 323: 27-32
50. Brown GC: Reversible binding and inhibition of catalase by nitric oxide. Eur J Biochem, 1995; 232: 188-91
51. Takemura S, Minamiyama Y, Imaoka S et al: Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia. J Hepatol, 1999; 30: 1035-44
52. Welters ID, Menzebach A, Goumon Y et al: Morphine inhibits NF-κB nuclear binding in human neutrophils and monocytes by a nitric oxide dependent mechanism. Anesthesiol, 2000; 92: 1677-84
53. Tubaro E, Borelli G, Croce C et al: Effect of morphine on resistance to infection. J Infect Dis, 1983; 148: 656-66
54. Weber RJ, Band LC, DeCosta B et al: Neural control of immune function: Opioids, opioid receptors and immunosuppression. NIDA Res Monogr, 1991; 105: 96-102
55. Perez-Castrillon JP, Perez-Arellano JP, Garcia-Palomo JD et al: Opioids depress in vitro human monocyte chemotaxis. Immunopharmacol, 1992; 23: 57-61
56. Stefano GB, Cadet P, Dokun A, Scharrer B: A neuroimmunoregulatory-like mechanism responding to electrical shock in the marine bivalve Mytilus edulis. Brain Behav Immun, 1990; 4: 323-29
57. Stefano GB, Hartman A, Bilfinger TV et al: Presence of the mu3 opiate receptor in endothelial cells: Coupling to nitric oxide production and vasodilation. J Biol Chem, 1995; 270: 30290-93
58. Stefano GB, Leung MK, Bilfinger TV, Scharrer B: Effect of prolonged exposure to morphine on responsiveness of human and invertebrate immunocytes to stimulatory molecules. J Neuroimmunol, 1995; 63: 175-81
59. Stefano GB, Scharrer B, Smith EM et al: Opioid and opiate immunoregulatory processes. Crit Rev in Immunol, 1996; 16: 109-44
60. Rojavin M, Szabo I, Bussiere JL et al: Morphine treatment in vitro or in vivo decreases phagocytic functions of murine macrophages. Life Sci, 1993; 53: 997-1006
61. Makman MH, Bilfinger TV, Stefano GB: Human granulocytes contain an opiate receptor mediating inhibition of cytokine-induced activation and chemotaxis. J Immunol, 1995; 154: 1323-30
62. Sonetti D, Mola L, Casares F et al: Endogenous morphine levels increase in molluscan neural and immune tissues after physical trauma. Brain Res, 1999; 835: 137-47
63. Stefano GB, Scharrer B: Endogenous morphine and related opiates, a new class of chemical messengers. Adv Neuroimmunol, 1994; 4: 57-68
64. Stefano GB, Salzet M, Magazine HI, Bilfinger TV: Antagonist of LPS and IFN-g induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. J Cardiovasc Pharmacol, 1998; 31: 813-20
65. Stefano GB, Cadet P, Breton C et al: Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: Evidence for a cell surface estrogen receptor. Blood, 2000; 95: 3951-58
66. Moncada S: Nitric oxide. J Hypertens Suppl, 1994; 12: S35-39
67. Kruskal BA, Shak S, Maxfield FR: Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci USA, 1986; 83: 2919-23
68. Welters ID, Fimiani C, Bilfinger TV, Stefano GB: NF-κB, nitric oxide and opiate signaling. Medical Hypotheses, 1999; 54: 263-68
69. Xie QW, Kashiwahara Y, Nathan C: Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem, 1994; 269: 4705-8
70. Nathan C, Xie QW: Regulation of biosynthesis of nitric oxide. J Biol Chem, 1994; 269: 13725-28
71. You HJ, Choi CY, Jeon YJ et al: Suppression of inducible nitric oxide synthase and tumor necrosis factor-alpha expression by 4-nonylphenol in macrophages. Biochem Biophys Res Commun, 2002; 294: 753-59
72. Barnhart A, Orona E: Nitric oxide synthase staining in lobster olfactory system. Chem Senses, 1994; 19: 438-42
73. Prabhakar S, Short DB, Scholz NL, Goy MF: Identification of nitric oxide-sensitive and -insensitive forms of cytoplasmic guanylate cyclase. J Neurochem, 1997; 69: 1650-60
74. Scholz NL, Chang ES, Graubard K, Truman JW: The NO/cGMP pathway and the development of neural networks in postembryonic lobsters. J Neurobiol, 1998; 34: 208-26
75. Martinez A, Riveros-Moreno V, Polak JM et al: Nitric oxide (NO) synthase immunoreactivity in the starfish Marthasterias glacialis. Cell Tissue Res, 1994; 275: 599-603
76. Adam-Vizi V, Allen TJ, Baker PF: The effects of nitroprusside and putative agonists on guanylate cyclase activity in squid giant axons. Biochimica et Biophysica Acta, 1988; 938: 461-68
77. Cooke IR, Edwards SL, Anderson CR: The distribution of NADPH diaphorase activity and immunoreactivity to nitric oxide synthase in the nervous system of the pulmonate mollusc Helix aspersa. Cell Tiss Res, 1994; 277: 565-72
78. Mahadevan A, Lappe J, Rhyne RT et al: Nitric oxide inhibits the rate and strength of cardiac contractions in the lobster Homarus americanus by acting on the cardiac ganglion. J Neurosci, 2004; 24: 2813-24
79. Gomez-Mendikute A, Etxeberria A, Olabarrieta I, Cajaraville MP: Oxygen radicals production and actin filament disruption in bivalve haemocytes treated with benzo(a)pyrene. Mar Environ Res, 2002; 54: 431-36
80. Stefano GB, Prevot V, Beauvillain JC et al: Estradiol coupling to human monocyte nitric oxide release is dependent on intracellular calcium transients: Evidence for an estrogen surface receptor. J Immunol, 1999; 163: 3758-63
81. Stefano GB, Goumon Y, Casares F et al: Endogenous morphine. Trends in Neurosciences, 2000; 9: 436-42
82. Scholz NL, Labenia JS, de Vente J et al: Expression of nitric oxide synthase and nitric oxide-sensitive guanylate cyclase in the crustacean cardiac ganglion. J Comp Neurol, 2002; 454: 158-67