Deletion of the novel oocyte-enriched gene, Gpr149, leads to increased fertility in mice

Endocrinology

Volumn 151, Issue 1, 2010, Pages 358-368

  Edson, Mark A ^a   Lin, Yi Nan ^a,b   Matzuk, Martin M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D2; FOLLITROPIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GPR 149 PROTEIN; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; COMPUTER MODEL; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; FEMALE FERTILITY; FERTILIZATION; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENOTYPE; GERMINAL VESICLE; GRANULOSA CELL; HORMONE DETERMINATION; MEIOSIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; OOCYTE MATURATION; OVARY FOLLICLE DEVELOPMENT; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; FEMALE; FERTILITY; GENE DELETION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; OOCYTES; ORGAN SPECIFICITY; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY; UP-REGULATION;

EID: 73649129249     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0760     Document Type: Article

References (48)

1. Lagerström MC, Schiöth HB2008 Structural diversity of Gprotein coupled receptors and significance for drug discovery. Nat Rev Drug Discov 7:339-357
2. Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA 2003 The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci USA 100:4903-4908
3. Kolakowski Jr LF 1994 GCRDb: a G-protein-coupled receptor database. Receptors Channels 2:1-7
4. Fredriksson R, Lagerström MC, Lundin LG, Schiöth HB 2003 The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63:1256-1272
5. Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, Catterall WA, Davenport AP, Delagrange P, Dollery CT, Foord SM, Gutman GA, Laudet V, Neubig RR, Ohlstein EH, Olsen RW, Peters J, Pin JP, Ruffolo RR, Searls DB, Wright MW, Spedding M 2009 IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels. Nucleic Acids Res 37:D680-D685
6. Hinckley M, Vaccari S, Horner K, Chen R, Conti M 2005 The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes. Dev Biol 287:249-261
7. Ledent C, Demeestere I, Blum D, Petermans J, Hämä läinen T, Smits G, Vassart G 2005 Premature ovarian aging in mice deficient for Gpr3. Proc Natl Acad Sci USA 102:8922-8926
8. Mehlmann LM, Saeki Y, Tanaka S, Brennan TJ, Evsikov AV, Pendola FL, Knowles BB, Eppig JJ, Jaffe LA 2004 The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes. Science 306:1947-1950
9. Matzuk MM, Burns KH, Viveiros MM, Eppig JJ 2002 Intercellular communication in the mammalian ovary: oocytes carry the conversation. Science 296:2178-2180
10. Edson MA, Nagaraja, AK, Matzuk MM, 2009 The mammalian ovary from genesis to revelation. Endocr Rev 30:624-712
11. Mehlmann LM, Jones TL, Jaffe LA2002 Meiotic arrest in the mouse follicle maintained by a Gs protein in the oocyte. Science 297:1343-1345
12. Freudzon L, Norris RP, Hand AR, Tanaka S, Saeki Y, Jones TL, Rasenick MM, Berlot CH, Mehlmann LM, Jaffe LA 2005 Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein. J Cell Biol 171:255-265
13. Friedel RH, Stubbusch J, Barde YA, Schnürch H 2001 A novel 7-transmembrane receptor expressed in nerve growth factor-dependent sensory neurons. Mol Cell Neurosci 17:31-40
14. Kurrasch DM, Cheung CC, Lee FY, Tran PV, Hata K, Ingraham HA 2007 The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. J Neurosci 27:13624-13634
15. De Smet C, Nishimori H, Furnari FB, Bögler O, Huang HJ, Cavenee WK2002Anovel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression. J Neurochem 81:575-588
16. Rovati GE, Capra V, Neubig RR 2007 The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71:959-964
17. Andreu-Vieyra C, Lin YN, Matzuk MM 2006 Mining the oocyte transcriptome. Trends Endocrinol Metab 17:136-143
18. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R, Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB 2004 A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 101:6062-6067
19. Roy A, Lin YN, Agno JE, DeMayo FJ, Matzuk MM2007 Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J 21:1013-1025
20. Nagaraja AK, Andreu-Vieyra C, Franco HL, Ma L, Chen R, Han DY, Zhu H, Agno JE, Gunaratne PH, DeMayo FJ, Matzuk MM 2008 Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol 22:2336-2352
21. Liu P, Jenkins NA, Copeland NG 2003 A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13:476-484
22. Adams DJ, Quail MA, Cox T, van der Weyden L, Gorick BD, Su Q, Chan WI, Davies R, Bonfield JK, Law F, Humphray S, Plumb B, Liu P, Rogers J, Bradley A 2005 A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction. Genomics 86:753-758
23. Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, Lee E, Alt FW, Westphal H 1996 Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci USA 93:5860-5865
24. Goldman JM, Murr AS, Cooper RL 2007 The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol 80:84-97
25. Cheng G, Weihua Z, Mäkinen S, Mäkelä S, Saji S, Warner M, Gustafsson JA, Hovatta O2002 A role for the androgen receptor in follicular atresia of estrogen receptor β knockout mouse ovary. Biol Reprod 66:77-84
26. Pangas SA, Li X, Robertson EJ, Matzuk MM 2006 Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice. Mol Endocrinol 20:1406-1422
27. Livak KJ, Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2[-ΔΔC(T)] method. Methods 25:402-408
28. Pan H, O'brien MJ, Wigglesworth K, Eppig JJ, Schultz RM 2005 Transcript profiling during mouse oocyte development and the effect of gonadotropin priming and development in vitro. Dev Biol 286:493-506
29. Zeng F, Baldwin DA, Schultz RM 2004 Transcript profiling during preimplantation mouse development. Dev Biol 272:483-496
30. Letunic I, Doerks T, Bork P 2009SMART6: recent updates and new developments. Nucleic Acids Res 37:D229-D232
31. Nelson JF, Felicio LS, Randall PK, Sims C, Finch CE 1982 A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. Biol Reprod 27:327-339
32. Sicinski P, Donaher JL, Geng Y, Parker SB, Gardner H, Park MY, Robker RL, Richards JS, McGinnis LK, Biggers JD, Eppig JJ, Bronson RT, Elledge SJ, Weinberg RA 1996 Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis. Nature 384:470-474
33. Otsuka F, Yamamoto S, Erickson GF, Shimasaki S 2001 Bone morphogenetic protein-15 inhibits follicle-stimulating hormone (FSH) action by suppressing FSH receptor expression. J Biol Chem 276:11387-11392
34. Orisaka M, Orisaka S, Jiang JY, Craig J, Wang Y, Kotsuji F, Tsang BK 2006 Growth differentiation factor 9 is antiapoptotic during follicular development from preantral to early antral stage. Mol Endocrinol 20:2456-2468
35. Buccione R, Vanderhyden BC, Caron PJ, Eppig JJ 1990 FSH-induced expansion of the mouse cumulus oophorus in vitro is dependent upon a specific factor(s) secreted by the oocyte. Dev Biol 138:16-25
36. Pangas SA, Choi Y, Ballow DJ, Zhao Y, Westphal H, Matzuk MM, Rajkovic A 2006 Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci USA 103:8090-8095
37. Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM2004 NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science 305:1157-1159
38. Eggerickx D, Denef JF, Labbe O, Hayashi Y, Refetoff S, Vassart G, Parmentier M, Libert F 1995 Molecular cloning of an orphan Gprotein-coupled receptor that constitutively activates adenylate cyclase. Biochem J 309(Pt 3):837-843
39. Tanaka S, Ishii K, Kasai K, Yoon SO, Saeki Y 2007 Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 upregulates cyclic AMP levels and promotes neurite outgrowth. J Biol Chem 282:10506-10515
40. Uhlenbrock K, Gassenhuber H, Kostenis E 2002 Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors. Cell Signal 14:941-953
41. Levoye A, Dam J, Ayoub MA, Guillaume JL, Jockers R 2006 Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers. EMBO Rep 7:1094-1098
42. Milligan G, Smith NJ 2007 Allosteric modulation of heterodimeric G-protein-coupled receptors. Trends Pharmacol Sci 28:615-620
43. Pfaff DW, Kow LM, Loose MD, Flanagan-Cato LM 2008 Reverse engineering the lordosis behavior circuit. Horm Behav 54:347-354
44. Nelson JF, Gosden RG, Felicio LS 1985 Effect of dietary restriction on estrous cyclicity and follicular reserves in aging C57BL/6J mice. Biol Reprod 32:515-522
45. Yan C, Wang P, DeMayo J, DeMayo FJ, Elvin JA, Carino C, Prasad SV, Skinner SS, Dunbar BS, Dube JL, Celeste AJ, Matzuk MM2001 Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol 15:854-866
46. Hanrahan JP, Gregan SM, Mulsant P, Mullen M, Davis GH, Powell R, Galloway SM 2004 Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries). Biol Reprod 70:900-909
47. McNatty KP, Smith P, Moore LG, Reader K, Lun S, Hanrahan JP, Groome NP, Laitinen M, Ritvos O, Juengel JL 2005 Oocyte-expressed genes affecting ovulation rate. Mol Cell Endocrinol 234:57-66
48. Valverde O, Célérier E, Baranyi M, Vanderhaeghen P, Maldonado R, Sperlagh B, Vassart G, Ledent C 2009 GPR3 receptor, a novel actor in the emotional-like responses. PloS One 4:e4704